PPT-NSCLC: Epidemiology and disease characteristics

NSCLC nonsmall cell lung cancer Lung cancer incidence and mortality 1 One of the most common cancers with 2 million new cases worldwide in 2018 The most common cause of cancer death causing nearly . Epidemiology. What is epidemiology?. How a disease is distributed in a population of people. What are the three main categories of epidemiological clues? . Person. Place. Time. What is a hypothesis? . Principles of Epidemiology. A. Epidemiology is the study of the factors influencing the frequency and distribution of diseases. 1. communicable diseases – diseases that can be transmitted from one host to another . Nathan Pennell, M.D., Ph.D.. September 6, 2014. Objectives. Discuss the role of chemotherapy in molecularly defined populations. Discuss the addition of chemo and/or bevacizumab (Avastin) to targeted therapy. Intervista a Federico . Cappuzzo. Background:. Programmed death-ligand 1 (PD-L1) expression on tumor cells (TC) or tumor-infiltrating immune cells (IC) is associated with OS, PFS and ORR in pts with advanced NSCLC treated with atezolizumab (anti-PDL1, MPDL3280A; Spigel et al, Spira et al, ASCO 2015), indicating that PD-L1 expression on both TC and IC is important for anti-tumor immunity. However, these 2 distinct expression patterns suggest the existence of previously unidentified NSCLC subtypes with distinct immunologic profiles. . MD. The Evolving Treatment Landscape in NSCLC: Congress Updates. Outline of Talk. Provide a brief overview of current advances in the treatment of NSCLC. EGFR-targeted agents . ALK-EML4 targeted agents . Epidemiology Part 2:. Epidemiology in an FAD Outbreak. Adapted from the . FAD . PReP. /NAHEMS Guidelines: Surveillance, Epidemiology, and Tracing (. 2014).. Describes the epidemiology investigation and response. Dr Tan . Jiunn. Liang. Clinical Specialist (Respiratory Medicine). Department of Medicine. Universiti. Malaya Medical Centre. Disclaimer. This program is provided as a service to the medical profession and represents the opinions of the speakers, not necessarily those of Merck or MSD or its affiliates. The Cancer genome atlas (TCGA) and the search for a CUP genetic/epigenetic signature Manel Esteller , MD, PhD. Director, Josep Carreras Leukaemia Research Institute (IJC) Director, Cancer Epigenetics and Biology Program (PEBC) November2020Page 1of 3EpidemiologyEvent SummaryEpidemiology provides members with the opportunity to gain knowledge in regard to health and diseasein populations This competitive event consists of a w Epidemiology is considered the basic science of public health and with good reason Epidemiology is a a quantitative basic science built on a working knowledge of probability statistics and sound resea 854IntroductionHippocrates around 46031370 BCE tell what epidemic diseases will a29ack and what each individual will be in danger of experiencing from the change of regimen148 Hence he introduced the . Alkhaldi. Community Medicine 2015/ 1016. Faculty of Medicine, The University of Jordan. 2. Definitions…. Public health. The science & art of . . P. reventing disease, . prolonging life, . Professor Rachel Butler. The genomic complexity of advanced NSCLC. Jordan et al. Cancer Discovery (2017). >50% NSCLC now have actionable variant. Treatment algorithm. NHSE: National Genomic Test Directory. Intervista a Federico . Cappuzzo. Background:. Programmed death-ligand 1 (PD-L1) expression on tumor cells (TC) or tumor-infiltrating immune cells (IC) is associated with OS, PFS and ORR in pts with advanced NSCLC treated with atezolizumab (anti-PDL1, MPDL3280A; Spigel et al, Spira et al, ASCO 2015), indicating that PD-L1 expression on both TC and IC is important for anti-tumor immunity. However, these 2 distinct expression patterns suggest the existence of previously unidentified NSCLC subtypes with distinct immunologic profiles. .