4152015 Discussion objectives Management of penetrating renovascular trauma Colonic anastomosis after damage control laparotomy Is it worth the risk Anticoagulation management strategies after IVC injuries requiring ligation of IVC ID: 188677
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Slide1
Chicago Metropolitan Trauma Society4/15/2015
Discussion objectives
Management of penetrating
renovascular
trauma
Colonic anastomosis after damage control laparotomy – Is it worth the risk?
Anticoagulation management strategies after IVC injuries requiring ligation of IVC. Slide2
Traumatic Colon Injury and Open Abdomen – Is anastomosis worth the risk?
Greg Day MD
Loyola University
Medical CenterSlide3
Patient - CC
Presentation
22 y/o Male s/p stab to the left flank
Primary Survey
Airway – intact, shallow respirations
Breathing – Bilateral breath sounds
Circulation –
tachycardic
120s, hypotensive to 70’s, weakly palpable femoral pulses bilaterallySlide4
Patient CC
Secondary Survey
Pertinent findings
Neuro
– Awake, alert, responsive to questions – c/o
abd
pain
Abd
– Left flank stab
approx
3cm in length, active bleeding from site, digital probe beyond fascia
No other injuries noted
Resuscitation
CVC placed
Massive transfusion protocol activated
First units of blood transfusing while going to ORSlide5
Operative and Hospital Course
Operative Findings
Large
hemoperitoneum
, Grade V injury to left renal hilum. Descending colon injury >50% circumference.
Colon resected, left in discontinuity
Left nephrectomy performed.
Procedure complicated by cardiac arrest
ACLS x20 minutes – ROSC
Abdomen packed,
abthera
placed and patient to ICU for resuscitationSlide6
Resuscitation
In OR
3L IVF, 12u PRBCs, 13u FFP, 2
Plt
ICU Care
Hypoxemia resolved over next 24-36 hours
Vasopressors weaned off
Acidosis resolved, base deficit clearedSlide7
Hospital Course
Return to OR POD 2 for abdominal washout, primary colonic anastomosis and replacement of
vac
POD 5 – return to OR for
fascial
closure
POD 8 – Patient with stool from midline wound – return to OR for resection of anastomosis, end colostomy
Patient Discharged to home three weeks from injury
Stoma reversed successfully 6 months laterSlide8
Prior to Colonic Anastomosis
Pt
Base deficit had cleared
Vasopressors were off
Transfusion requirements post op were minimal
Bowel appeared viable
Why was it not successful? Slide9
Colonic Anastomosis in TraumaSlide10
Colon Anastomosis in Trauma
1979 Stone/Fabian found that in the stable patient, primary repair can be performed safely at initial operation without diversion
This was subsequently confirmed
with following studies with
primary anastomosis also
Seeing good results
How then does the open
Abdomen affect your ability
to perform an anastomosis?Slide11
Damage Control Laparotomy
“Damage Control” – Procedures and skills used to maintain/restore the watertight integrity, stability or offensive power of a warship.
Damage Control Surgery – limit surgery to essential interventions – Control hemorrhage, limit enteric contamination
Decision to perform damage control
Clinical decision
Objective signs
Temp < 35C
pH <7.2
Base Deficit - > 15mmol/L
INR > 50% of normalSlide12
When is anastomosis appropriate?
Difficult to study prospectively
Most data at this time is retrospective in nature
Why risk it?
Repeat operations incur high riskSlide13
78 Damage Control Laparotomy with colon injury – 61 analyzed
Findings
16% leak rate of those patients receiving anastomosis
In comparison to 1-3% leak rate in non damage control surgery
Leaks – longer ICU stay, decreased likelihood of
fascial
closure
Risks for Leaks
Older Age
Failure to close fascia in five days
This study also had 2/10 leaks in a
defunctionalized
anastomosis
Question then – does proximal diversion help in trauma setting?
Anastomotic breakdown is suggested to be more related to physiology of severe injurySlide14
68 Patients with DCS with colonic injury41 with anastomosis, 27 diverted
Leak = suture line disruption or EC fistula
Leak rate – DCS compared to Non-DCS
17%-6%
When comparing leak
vs
no leak
No difference in transfusion requirement, anastomosis technique
They did find significant difference in leak rate in those patients with vasopressor use between DC and operation when anastomosis was performedSlide15
Colon Anastomosis After Damage Control Laparotomy: Recommendations From 174 Trauma ColectomiesOtt
, Mickey M. MD; Norris, Patrick R. PhD; Diaz, Jose J. MD; Collier, Bryan R. DO; Jenkins, Judith M. MSN; Gunter, Oliver L. MD; Morris, John A. Jr. MD
Goal to compare leak rates between open
abd
pts
and those primarily closed at first operation
174 patients with DCS with colonic injury
58 with fecal diversion, 116 with colonic anastomosisSlide16
Colon Anastomosis After Damage Control Laparotomy: Recommendations From 174 Trauma ColectomiesOtt
, Mickey M. MD; Norris, Patrick R. PhD; Diaz, Jose J. MD; Collier, Bryan R. DO; Jenkins, Judith M. MSN; Gunter, Oliver L. MD; Morris, John A. Jr. MDSlide17
How should we proceed?
Trauma patients who require damage control operations are under more physiologic stress
Markers of transfusion requirements, acidosis, temperature, and vasopressor requirements are surrogates to prove their stressed state
It is these factors one must consider when discussion anastomosis after a patient has an open abdomenSlide18
How has the literature helped
Patients with massive transfusion requirements, left sided colon injuries and vasopressor requirements should most often be diverted
Consideration of anastomosis beyond those factors remains a clinical judgment call. Slide19
Anticoagulation management after IVC ligation
Harold Bach MD
Loyola University Medical CenterSlide20
AB 2767036
22 y/o male involved in altercation at a bar
Sustained GSW to abdomen, mid-
epigastric
region
Unstable at OSH (Level II trauma center), so taken immediately to OR
Liver injury attempted to be repairedSlide21
AB 2767036
Upon arrival to trauma bay, patient intubated and sedated
PRBC transfusing
HR 115 BP 140 systolic
Abdomen open and packed
Taken back to OR for explorationSlide22
AB 2767036
At OR, diagnosed injuries included:
shredded
IVC,
multiple
areas of bleeding from IVC side branches and side branches of aorta,
aorta
without obvious injuries,
injury
to lumbar vertebral body,
supraceliac
aortic clamping time 50 minutes.Slide23
Procedures included:Damage Control Exploratory laparotomy,
ligation of
infrarenal
IVC,
packing
of liver with
Vicryl
mesh,
packing
of abdomen,
Abdomen left open
with Bogota
closure
Taken back to ICU for resuscitation
AB 2767036Slide24
Stabilized, taken back to OR PID #2Found to additionally have a pancreatic head injury and small bowel
serosal
injury
Reexploration
of recent laparotomy,
removal
of packing,
abdominal
washout,
placement
of
drains to
retroperitoneum
,
abthera
vac
placement
AB 2767036Slide25
Returned to OR 2x more, eventually closed with feeding jejunostomy tube placed
Post op course complicated by patient self-discontinuing retroperitoneal drains requiring IR replacement
Began on
coumadin
, discharged home
AB 2767036Slide26
Abdominal IVC injuries
Incidence
Penetrating 0.5-5%
Blunt 0.6-1%
Mortality
19%-66% in literature, widely reported around 40%Slide27
Rx:Lateral venorrhaphy
Patient stable
Technically feasible
Must have >25% luminal diameter remaining
IVC ligation
Damage controlSlide28
The first report of an IVC ligation was by Kocher (1883).
Bilroth
performed the procedure in 1885
.
These were for iatrogenic injuries to during
surgery for malignant disorders in two patients.
Both
of these patients demised.
The first record of an
infrarenal
vena
caval
ligation with a successful outcome was by
Bottini
.
Detrie
reported the first survivor after a suprarenal
ligation.
By
1949 there were 136 reports of
caval
ligations in the literature. Slide29
DeBakey et al reported the first large series of AVC injuries in 1978. 301
patients who had been identified with
caval
injuries
/ 30
years.
The
majority (234) were treated with repair while only 32 received
caval
ligation.
Initial
mortality rates in the 1950’s approached 100%. Slide30
It was also historically a procedure employed to halt the
propogation
of LE DVT prior to anticoagulation therapy.Slide31
Sequelae of IVC ligation
In repaired IVC, recommend surveillance via US or CT
Ligated IVC?
Anticoagulation?
Role of prophylactic
fasciotomies
?Slide32
Questions:
What are the EAST guidelines on treatment with anticoagulation after ligation of the
infrarenal
IVC?
A) 3 months therapeutic anticoagulation
B) 6 months therapeutic anticoagulation
C) lifetime anticoagulation
D) there are no guidelines for treatment
Answer - DSlide33
Question
Current guidelines suggest that patients with a destructive colon injury can undergo resection and primary anastomosis if
A – There is no evidence of shock
B – Minimal underlying disease
C – Minimal associated injuries
D – There is no peritonitis
E – All the above are present
Answer - ESlide34
Question
True/False : In penetrating
renovascular
trauma, preliminary vascular control decreases blood transfusions, decreases rate of nephrectomy and decreases blood loss.
Answer – False – Preliminary vascular
Control has no impact on the above. Slide35