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Intro to Poisons: Intro to Poisons:

Intro to Poisons: - PowerPoint Presentation

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Intro to Poisons: - PPT Presentation

The Poisoners Handbook Forensic Science 21715 No Drill Drill Quiz Take out a sheet of notebook paper and copy down these drills question AND answer 129 23 When done get a copy of How Toxic is Toxic and finish working on the questions ID: 368550

test drug substance drugs drug test drugs substance poisons forensic toxic identification preliminary tests poison identify analysis handbook poisoner

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Slide1

Intro to Poisons:The Poisoner’s Handbook

Forensic Science

2/17/15Slide2

No Drill – Drill QuizTake out a sheet of notebook paper and copy down these drills, question AND answer:

1/29, 2/3

When done, get a copy of “How Toxic is Toxic?” and finish working on the questions.Slide3

ObjectivesIWBATClassify and identify multiple poisons. List their effects and the tests used to detect the poison.

Define LD

50

and apply the concept to poisoning.Slide4

Pd. 5 – Drug Identification

The challenge

of

forensic drug identification comes in selecting analytical procedures that will ensure a specific identification of a drug.

This plan, or scheme of analysis, is divided into two phases.

Screening test that is

preliminary to

reduce the possibilities to a manageable number.Confirmation test that is a single test that specifically identifies a substance.

DRUGSSlide5

Preliminary Analysis

Faced with the prospect that the unknown substance may be any one of a thousand or more commonly encountered drugs, the analyst must employ screening tests to reduce these possibilities to a small and manageable number.

DRUGSSlide6

Confirmational Determination

Once this preliminary analysis is completed, a

confirmational

determination is pursued.

Forensic chemists will employ a specific test to identify a drug substance to the exclusion of all other known chemical substances.

Typically infrared

spectrophotometry

or gas chromatography-mass spectrometry is used to specifically identify a drug substance.

DRUGSSlide7

IR Spectrum of CocaineSlide8

IR Spectrum of NovocaineSlide9

Collection and Preservation

The field investigator has the responsibility of ensuring that the evidence is properly packaged and labeled for the laboratory.

Generally common sense is the best guide, keeping in mind that the package must prevent the loss of the contents and/or cross-contamination.

DRUGSSlide10

Often the original container in which the drug was seized will suffice.

All packages must be marked with information that is sufficient to ensure identification by the officer in the future and establish the chain of custody. Slide11

How Toxic is Toxic?What is LD50

? Why is it a

useful concept?

What are the concerns with using LD

50

? Is it always useful??Slide12

The Poisoner’s Handbook

We will be watching “The

Poisoner’s

Handbook,” a PBS special about the rise of forensic science in New York City, focusing on the poisons that were common causes of death in the 20s and 30s.

While watching the video, keep track of all of the poisons mentioned in the video, along with their effects, tests for them, and famous cases.

Also, take notes on Alexander

Gettler

and Charles Norris—who were they? What role did their personalities and backgrounds play in their lives?Slide13

ClosureList one poison discussed in today’s segment

Symptoms of poisoning

Test used by the scientists

Famous case involving this poison