1 Color Tests presumptive Narrows down type of drug Fast Simple Cannot be used in court Color Test Drug Positive Result 1 Marquis ID: 599873
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Slide1
IV. Screening for DrugsSlide2
1. Color Tests (
presumptive)
Narrows down type of drugFastSimple
Cannot
be used in court!Slide3
Color Test: Drug
Positive Result
__1) Marquis Heroin
Morphine
Ecstasy2) Cobalt Thiocyanate Cocaine
3) Dillie-Koppanyi Barbituates
4) VanUrk LSD
5)
Duquenois-Levine Marijuana
Deep Purplish Red
Deep Purplish Red
AmphetamineSlide4
Molecular Structures of Narcotics and Stimulants
amphetamineSlide5
Marquis Reagent
Test for opiates (heroin, morphine, codeine), ecstasy, and amphetamines
Positive results:Slide6
Cobalt thiocynate
Test
a.k.a. Scott TestCocaine- Positive test = blue solutionSlide7
Dillie-Koppanyi
Test
Positive test = violet-blue solutionSlide8
VanUrk
Test
Positive test = blue-purple solution
Molecular Structure of LSD
(
D-lysergic acid diethylamide)Slide9
Marijuana
THC (
tetrahydrocannabinol
)Slide10
Duquenois
-Levine Reagent
Positive test = purple; ibuprofen can cause a false positiveSlide11
2. Microcrystalline Test (
confirmation
)
chemical
rxn
between drug
&
a reagent (specific chemical) that produces a unique crystal
precipitate
Size and
shape of crystals formed are highly characteristic of specific drugs.
Heroine- “K”
Cocaine-crossSlide12
3. Spectrophotometry (
confirmation)
UV light and IR light are absorbed by drugThe
wavelengths and intensity absorbed are unique for each drugSlide13
4. GC/Mass Spectrometry (
confirmation)
Sample is hit with high energy electrons that cause the drug to break apart Each drug breaks down differently
Produces plot of subproductsRapid screening and wide range of drugsSlide14
Detection Period of DrugsSlide15
V. Poisons Brief History
Hemlock, 399 BC
By 17th
century, people were quite adept at using poisons to kill people, especially arsenic.
Murder by poison not popular anymore. Why? (easier to get gun than controlled substances)Slide16
VI. Vocab
Poison
Naturally occurring or manufactured substance that can cause severe harm or death if ingested, inhaled, absorbed, or injected.
Toxin Poisonous substance produced by certain plants, animals, or bacteria; capable of causing disease or death (subgroup of poisons). Slide17
A. Poisons
Generally enter the body in a single, massive dose
Can be counteracted by prompt treatmentMost organ damage is repairable (except CNS)
ID’ed by their symptomsMany disguise themselvesSlide18
B. Toxicity and Toxic Agents
1. Toxicity
degree to which a substance is poisonous or can cause harmimportant factors:
dose (how much)duration (how long)exposure (inhale, ingest, inject)
nature of the drug (how it interacts with body and other substances)2. Toxic Agents– alcohol, drugs, heavy metals, solvents & vapors, radiation, pesticides, and plant/animal toxinsSlide19
C. Immunoassay
a biochemical test that measures the presence
of
a molecule through the use of an antibody (usually) or an antigenused to detect a variety of drugs and poisons in
saliva, urine