antsandmanyotherspeciescommonininhabitedareas Theseantscannotstingbutsprayavenomcomprising primarilyformicacidwhichburnsandirritatesAlthough manyotherspeciescanstinghumansfewdowith regularityOnly ID: 211887
Download Pdf The PPT/PDF document "micinae.Theseincludecarpenterants,sugara..." is the property of its rightful owner. Permission is granted to download and print the materials on this web site for personal, non-commercial use only, and to display it on your personal computer provided you do not modify the materials and that you retain all copyright notices contained in the materials. By downloading content from our website, you accept the terms of this agreement.
micinae.Theseincludecarpenterants,sugarants,red antsandmanyotherspeciescommonininhabitedareas. Theseantscannotstingbutsprayavenomcomprising primarilyformicacid,whichburnsandirritates.Although manyotherspeciescanstinghumans,fewdowith regularity.Onlyahandfulofspeciesareknowntocause allergicreactionstovenom,andonlymembersofthree generacauseallergicreactionscommonlyenoughtobe importantmedicalproblems.Thesubfamiliesofantsand theplacementofthegeneradiscussedinthisrevieware listedinTable1. Stingingants Mostantsarenotaggressiveandrarelystinglargeorgan- inthemiddleeast[5].These twospeciesarecommonlyreferredtoasChineseneedle antsandsamsumants. InAustraliathelargeantsofthegenus Myrmecia ,especi- ally M.pilosula ,areimportantcausesofstingallergy[6]. Anumberofspeciesofmyrmicineants,especiallycertain harvesterantsofthegenus Pogonomyrmex willsting, especiallyinthesouthwesternNorthAmericandesert [7].Anumberofotherspeciesofponerineantsareknown tostinghumansincluding permissiveenvironmentalanddietaryrequirements. Theseantsarecarriedonitemsininternationalcom- merceandarespreadastrampspecies[3,12].Adocu- mentedexampleistheÞndingofredimportedÞreants, S.invicta ,inawoodcargodeliveredfromSouthAmerica toSpain[12].TheredimportedÞreantisnowwell establishedinsouthernChinaandsoutheastAsia[13,14] andcanbefoundaroundBrisbaneAustralia[15].Spread BrodySchoolofMedicineatEastCarolinaUniversity, Greenville,NorthCarolina,USA CorrespondencetoDonaldR.Hoffman,PhD, ProfessorofPathologyandLaboratoryMedicine, Summary Antssharesomecommonproteinsinvenoms,buteachgroupappearstohavea numberofpossiblyuniquecomponents.Furtherproteomicstudiesshouldexpandand clarifyourknowledgeofthesefascinatinganimals. Keywords ant,Þreant,jackjumperant,phospholipase,sting,venom CurrOpinAllergyClinImmunol10:000000 2010WoltersKluwerHealth|LippincottWilliams&Wilkins 1528-4050 1528-4050 2010WoltersKluwerHealth|LippincottWilliams&WilkinsDOI:10.1097/ACI.0b013e328339f325 Copyright © Lippincott Williams & Wilkins. Unauthorized reproduction of this article is prohibited. CE:Namrta;ACI/5923;TotalnosofPages:5; ACI5923 venomallergens.Thiswillleadtocomponent-resolved diagnosisofallergicreactions[47].Recentadvances includetheproductionofacDNAlibraryandmicroarrays forgeneexpressionstudiesintheimportedÞreant, S.invicta [48],andthedevelopmentofFourmidable, whichisadatabaseforstudiesinantgenomics[49]. Therearepresentlyonlytwospecies, S.invicta and Lasius niger ,inthedatabase,butotherswillprobablybeaddedin thenearfuture. Conclusion Onlytwogroupsofstingingants,importedÞreantsand jackjumperants,havehadtheallergeniccomponentsof theirvenomsextensivelyinvestigated.Therearesome morelimitedstudiesofChineseneedleants,samsum antsandharvesterants.Antvenomsareheterogeneous withmanyexpressingcomponentsuniquetoeachgroup. FireantshaveSoli2and4,notdescribedinothervenoms aswellasacomplexmixofpiperidinealkaloids.Jack jumperandrelatedantsproducepilosulins,notfoundin otherantgroups.Someenzymes,especiallyphospho- lipaseA 1 B,maybeexpressedinmany,ifnotmostant venoms.Anothergroupofproteinscommonlyfoundare membersoftheAntigen5/Soli3family.Theseproteins arealsotypicalofwaspvenoms. Referencesandrecommendedreading Papersofparticularinterest,publishedwithintheannualperiodofreview,have beenhighlightedas: ofspecialinterest ofoutstandinginterest AdditionalreferencesrelatedtothistopiccanalsobefoundintheCurrent WorldLiteraturesectioninthisissue(pp.000Ð000). 1 www.antweb.org(accessed2/2/2010). 2 TankersleyMS.ThestingingimpactoftheimportedÞreant.CurrOpinAllergy ClinImmunol2008;8:354Ð359. 3 HoffmanDR.ReactionstolesscommonspeciesofÞreants.JAllergyClin Immunol1997;100:679Ð683. 4 YunY-Y,KoS-H,ParkJ-W,HongC-S.Anaphylaxistovenomofthe Pachycondyla speciesant.JAllergyClinImmunol1999;104:879Ð882. 5 DibG,GuerinB,BanksWA,LeynadierF.SystemicreactionstotheSamsum ant:anIgEmediatedhypersensitivity.JAllergClinImmunol1995;96:465Ð 472. 6 StreetMD,DonovanGR,BaldoBA,SutherlandS.Immediateallergicreac- tionsto Myrmecia antstings:immunochemicalanalysisof Myrmecia venoms. ClinExpAllergy1994;24:590Ð597. 7 PinnasJL,StrunkRC,WangTM,ThompsonHC.Harvesterantsensitivity:in vitroandinvivostudiesusingwholebodyextractsandvenom.JAllergyClin Immunol1977;59:10Ð16. 8 KlotzJH,deShazoRD,PinnasJL, etal. Adversereactionstoantsother thanimportedÞreants.AnnAllergyAsthmaImmunol2005;95:418Ð 425. 9 HaddadVJr,CardosoJL,MoraesRH.Descriptionofaninjuryinahuman causedbyafalsetocandira( Dinoponeragigantea ,Perty,1833)witha revisiononfolkloric,pharmacologicalandclinicalaspectsofthegiantants ofthegenera Paraponera and Dinoponera (sub-familyPonerinae).RevInst MedTropSaoPaulo2005;47:235Ð238. 10 HaddadV,BicudoLRH,FransozoA.Thetriplariatreeand Pseudomyrmex ants:asymbioticrelationshipwithrisksofattackforhumans.RevSoc BrasileiraMedTrop2009;42:727Ð729. 11 SolleyGO.AllergytostingingandbitinginsectsinQueensland.MedJAust 1990;153:650Ð654. 12 Fernandez-MelendezS,MirandaA,Garcia-GonzalezJJ, etal. Anaphylaxis causedbyimportedredÞreantstingsinMalaga,Spain.JInvestigAllergolClin Immunol2007;17:48Ð49. 13 ChenC,GongW,HuB, etal. Potentialestablishmentareasof Solenopsis invicta inChina:apredictionbasedonGIS.YingYongShengTaiXueBao 2006;17:2093Ð2097. 14 WuBQ,LuYY,ZengL,LiangGW.Inßuencesof Solenopsisinvicta buren invasiononthenativeantcommunitiesindifferenthabitatsinGuangdong. YingYongShengTaiXueBao2008;19:151Ð156. 15 SolleyGO,VanderwoudeC,KnightGK.AnaphylaxisduetoredimportedÞre antsting.MedJAust2002;176:521Ð523. 16 KnightD,BangsMJ.Cutaneousallergicvasculitisdueto Solenopsisgemi- nata (Hymenoptera:Formicidae)envenomationinIndonesia.SoutheastAsian JTropMedPublicHealth2007;38:808Ð813. 17 LaiLC,HuaKH,YangCC, etal. SecretionproÞlesofvenomalkaloidsin Solenopsisgeminata (Hymenoptera:Formicidae)inTaiwan.EnvironEntomol 2009;38:879Ð884. 18 KhanSA,ShellehHH,KhanLA,ShahH.BlackÞreant( Solenopsisrichteri ) stingproducinganaphylaxis:areportof10casesfromNajran.AnnSaudiMed 1999;19:462Ð464. 19 NelderMP,PaysenES,ZungoliPA,BensonEP.Emergenceoftheintroduced ant Pachycondylachinensis (Formicidae:Ponerinae)asapublichealththreat inthesoutheasternUnitedStates.JMedEntomol2006;43:1094Ð1098. 20 NasoniaGenomeWorkingGroup,WerrenJH,RichardsS,DesjardinsCA, etal. Functionalandevolutionaryinsightsfromthegenomesofthreepara- sitoid Nasonia species.Science2010;327:343Ð348. 21 deGraafDC,AertsM,BrunainM, etal. Insightsintothevenomcompositionof theectoparasistoidwasp Nasoniaviripennis frombioinformaticandproteo- micstudies.InsectMolBiol2010;19(Suppl1):11Ð26. 22 WieseMD,ChatawayTK,DaviesNW, etal. Proteomicanalysisof Myrmecia pilosula (jackjumper)antvenom.Toxicon2006;47:208Ð217. 23 WieseMD,BrownSG,ChatawayTK, etal.Myrmeciapilosula (JackJumper) antvenom:identiÞcationofallergensandrevisednomenclature.Allergy2007; 62:437Ð443. 24 BrownSG,HeddleRJ.Preventionofanaphylaxiswithantvenomimmunother- apy.CurrOpinAllergyClinImmunol2003;3:511Ð516. 25 ChenL,FadamiroHY.Re-investigationofvenomchemistryofSolenopsisÞre ants.II.IdentiÞcationofnovelalkaloidsin S.invicta .Toxicon2009;53:479Ð 486. 26 ChenL,FadamiroHY.Re-investigationofvenomchemistryofSolenopsisÞre ants.I.IdentiÞcationofnovelalkaloidsin S.richteri .Toxicon2009;53:469Ð 478. 27 HoffmanDR,DoveDE,JacobsonRS.AllergensinHymenopteravenomXX. IsolationoffourallergensfromimportedÞreant( Solenopsisinvicta )venom. JAllergyClinImmunol1988;82:818Ð827. 28 HoffmanDR.AllergensinHymenopteravenomXXIV:theaminoacidse- quencesofimportedÞreantvenomallergensSoliII,SoliIIIandSoliIV. JAllergyClinImmunol1993;91:71Ð78. 29 SchmidtM,WalkerRB,HoffmanDR,McConnellTJ.Cloningandsequencing ofcDNAencodingtheÞreantvenomproteinSoliII.FEBSLett1993; 319:138Ð140. 30 SchmidtM,McConnellTJ,HoffmanDR.Immunologiccharacterizationof recombinantÞreantvenomallergenSoli3.Allergy2003;58:342Ð349. 31 HoffmanDR,DoveDE,MofÞttJE,StaffordCT.AllergensinHymenoptera venomXXI.CrossreactivityandmultiplereactivitybetweenÞreantvenomand beeandwaspvenoms.JAllergyClinImmunol1988;82:828Ð834. 32 PadavattanS,SchmidtM,HoffmanDR,Markovic-HousleyZ.Crystalstructure ofthemajorallergenfromÞreantvenom,Soli3.JMolecBiol2008; 383:178Ð185. TheÞrstthree-dimensionalstructureofanantvenomallergen. 33 HoffmanDR,SakellRH,SchmidtM.Soli1,thephospholipaseallergenof importedÞreantvenom.JAllergyClinImmunol2005;115:611Ð616. 34 HoffmanDR,PeroutkaCM,SchmidtM.ImportedÞreantvenomphospho- lipase,Soli1,isaproteinallergen.JAllergyClinImmunol2008;121:S30. 35 HoffmanDR,SmithAM,SchmidtM, etal. AllergensinHymenopteravenom XXII:comparisonofvenomsfromtwospeciesofimportedÞreants, Sole- nopsisinvicta and richteri .JAllergyClinImmunol1990;85:988Ð996. 36 SchmidtM,McConnellTJ,HoffmanDR.Productionofarecombinantim- portedÞreantvenomallergen,Soli2,innativeandimmunoreactiveform. JAllergyClinImmunol1996;98:82Ð88. 37 SchmidtM,HoffmanDR.ExpressionofrecombinantÞreantvenomallergen Soli4.JAllergyClinImmunol2001;107:S112ÐS113. 4 Anaphylaxisandinsectallergy Copyright © Lippincott Williams & Wilkins. Unauthorized reproduction of this article is prohibited. CE:Namrta;ACI/5923;TotalnosofPages:5; ACI5923 38 SchmidtJO,BlumMS.Thebiochemicalconstituentsofthevenomofthe harvesterant, Pogonomyrmexbadius .CompBiochemPhysiolPartCComp Pharmac1978;61:239Ð247. 39 SchmidtJO,BlumMS.Aharvesterantvenom:chemistryandpharmacology. Science1978;200:1064Ð1066. 40 ReunalaT,Brummer-KorvenkontioH,SaarinenK, etal. Characterizationof IgE-bindingallergensinSamsumantvenom.JAllergyClinImmunol2005; 115:S108. 41 LeeEK,JeongKY,LyuDP, etal. Characterizationofthemajorallergensof Pachycondylachinensis inantstinganaphylaxispatients.ClinExpAllergy 2009;39:602Ð607. DescriptionoftheÞrstcharacterizedallergenfromChineseneedleantvenom. 42 SchwedeT,KoppJ,GuexN,PeitschMC.SWISS-MODEL:anautomated proteinhomology-modelingserver.NucleicAcidsRes2003;31:3381Ð 3385. 43 MoreauCS,BellCD,ArchibaldSB,PierceNE.Phylogenyoftheants: diversiÞcationintheageofangiosperms.Science2006;312:101Ð104. 44 JohnsonSR,CopelloJA,EvansMS,SuarezAV.Abiochemicalcharacteriza- tionofthemajorpeptidesfromthevenomofthegiantneotropicalhuntingant Dinoponeraaustralis .Toxicon2010;55:702Ð710. 45 PanJ,HinkWF.Isolationandcharacterizationofmyrmexins,sixisoforms ofvenomproteinswithanti-inßammatoryactivityfromthetropicalant, Pseudomyrmextriplarinus .Toxicon2000;38:1403Ð1413. 46 vonSicardNA,CandyDJ,AndersonM.Thebiochemicalcompositionof venomfromthepavementant( Tetramoriumcaespitum L.).Toxicon1989; 27:1127Ð1133. 47 deGraafDC,AertsM,DanneelsE,DevreeseB.Bee,waspandantvenomics pavethewayforacomponent-resolveddiagnosisofstingallergy.JProteo- mics2009;72:145Ð154. 48 WangJ,JemielityS,UvaP, etal. AnannotatedcDNAlibraryandmicroarrayfor large-scalegene-expressionstudiesintheant Solenopsisinvicta .Genome Biol2007;8:R9. 49 WurmY,UvaP,RicciF, etal. Fourmidable:adatabaseforantgenomics.BMC Genomics2009;10:5. Antvenoms Hoffman5