Daniel T Gryko 4 Nucleophilic Substitution of Hydrogen in the Synthesis of Aromatic Heterocyclic Compounds Modern Oxidation Nucleophilic substitution of hydrogen ID: 815179
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Slide1
MODERN ORGANIC SYNTHESIS
Daniel T. Gryko
4
.
Nucleophilic
Substitution of Hydrogen in
the
Synthesis of
Aromatic Heterocyclic
Compounds
+
Modern
Oxidation
Slide2Nucleophilic substitution of hydrogen - mechanism
Slide3Vicarious nucleophilic substitution of hydrogen -
mechanism
Slide4Oxidative
Slide5Indole
Slide6Indole
Slide7Indole
Slide8Indole
Slide9Indole
Slide10Indole – natural products
Slide11Indazole and 2,1-Benzisoxazole
Slide12Quinoline
Slide13Quinoline
Slide14Quinoline
Slide15Fused quinolines
Slide16Fused quinoxalines
Slide17Quinoxalines
Slide18Alkylation
Slide19Aldehydes
Slide20Dess-Martin Periodinane
Slide21IBX
Slide22TEMPO
Slide23MnO2 and BaMnO4
Slide24NaClO
Slide25Sodium chlorite - NaClO2
Slide26Ru
Slide27DMSO
Slide28NaWO4
Slide29Methyltrioxorhenium (MTO) MeReO3
Slide30M. Mąkosza
Chem. Rev. 2004, 104
, 2631.
M.
Mąkosza
,
Synthesis
,
2011
, 2341.
M.
Mąkosza
,
Heterocycles
,
2014
,
88
, 75.
Key
literature
Additional
literature
J. M.
Joo
Asian
JOC
.
2015
,
4
, 1386.