CSE5810: Intro to Biomedical Informatics

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The Role of AI in Clinical Decision  Support  . Saahil Moledina. University of Connecticut. saahil.moledina@uconn.edu. Clinical Decision Support in Biomedical Informatics:. CDS in Biomedical Informatics. ID: 317639 Download Presentation

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CSE5810: Intro to Biomedical Informatics

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CSE5810: Intro to Biomedical Informatics

The Role of AI in Clinical Decision  Support 

Saahil Moledina

University of Connecticut



Clinical Decision Support in Biomedical Informatics:


CDS in Biomedical Informatics


The Clinical Decision support in biomedical informatics is the knowledge that is provided to assist the clinician and/or patients for assisting them in making decisions regarding choice of treatment.

These decisions are tried to be made easy by giving the knowledge of the outcomes and complications of the treatment chosen.

Now, Clinical Decision Support systems are systems are systems designed to do the clinical decision support and process them using AI and machine learning.

For these systems to work efficiently it needs to combine the efforts of the patients, clinicians, nurses and decision aids.


CDS in Biomedical Informatics

Research Areas:

Artificial Intelligence

Machine Learning

User Interfaces

Data Mining

Data warehousing



Benefits of CDS:

Increased quality of care and enhanced health outcomes

Avoidance of errors and adverse events

Improved efficiency, cost-benefit, and provider and patient satisfaction


CDS in Biomedical Informatics



Clinicians, nurses, Physicians.




HL7 version 3( representation of patient data for Clinical decision support).

Infobutton ( Context-Aware Retrieval Application)


GLIF (knowledge representation)

Arden Syntax


knowledge representation


GELLO (Common Expression Language


Unified Medical Language

System and

component terminologies (e.g.,



CDS in Biomedical Informatics

An important aspect for clinical decision making is the patients perspective of their health problems and preferences for the treatment.

One of the biggest problem in clinical decision support systems is integrating the patient perspective in decision making.

For this we need to make the use of Shared Decision making (SDM).

This results into a new problem on how to develop a clinical decision support system for SDM.


CDS in Biomedical Informatics


CDS in Biomedical Informatics

Features of a Clinical Decision Support with SDM are:

Provide Clinicians with the health problems associated with a patient’s illness.

Treatment Options

Benefits and Risks of the treatment.

Patient Preferences.

Acceptable to the clinicians.


CDS in Biomedical Informatics

To make such a system knowledge about the following things are vital:

Clinical Domain

for understanding the decision problem. E.g. coronary artery.

Decision Science and research of SDM

to draw out the patient’s preferences.

Biomedical informatics

Algorithms and technologies.

Organizational knowledge

To adapt the system to the practices and workflows of the clinicians .

To adapt to the settings where these systems are used.


CDS in Biomedical Informatics

There are two major types of system used for drawing out the patient’s preferences in clinical decision making:

DA(Decision Aids)

Assists patients in difficult decision making.

It does that by giving the patients information about the various choices about the various treatments available and its outcome.

DA’s need to be working in supplementary of the clinician counseling.

Its seen that the results of the patients working with clinicians and DA’s have been really good.


CDS in Biomedical Informatics

DA’s are useful only when a decision is difficult. E.g. more than one treatment recommended, outcomes of the treatment uncertain, complications, tradeoff between outcomes or small chance of a grave outcome.

The drawback with DA’s is that these systems have narrow segment of decisions of choice of treatments hence other systems preferred.

CHOICE(Creating better Health Outcomes by Improving Communication about patients Expectations):

This system is for the clinicians to teach them how to draw out the preferences from a patient.


CDS in Biomedical Informatics

It is a system that is mostly used by nurses which collect the preferences from the patient bedside and integrate it in the model.

It has been seen that the congruence of the actual problem patient is having and patient’s self assessment is very high.

It is also easy to use.

Hence, CHOICE is used to develop, implement and evaluate CDSS for SDM.


CDS in Biomedical Informatics



CDS in Biomedical Informatics


CDS in Biomedical Informatics

Artificial Intelligence is used to process and analyze the data for Clinical Decision support since the framework of system in Biology and Medicine are very complex.

There are a lot of challenges that one has to face to implement these techniques.

These challenges are:

feature selection



data warehousing

data mining

analysis of the biological networks


CDS in Biomedical Informatics

Key Technical Problems:

Challenges in implementing AI.

Training the Dataset.

Developing generic Algorithm to handle data.

Integrating it with EHR’s

Out of Control Alerts.

Key People Problems:

Using the CDSS.

Poor UI.

Training the people to use the system.


CDS in Biomedical Informatics


Hence, this shows that the use of Clinical decision support system is necessary since it gives an improvement in the patient satisfaction because of his involvement in the decision of the treatment used to cure him/her. It also shows that there are many challenges that we have to face to make it as accurate and efficient as possible. But also one thing is clear that it is still not possible to replace the physician, clinician or nurse it can only assist them and it can never be fully trusted since it can never be 100% accurate.


Thank You






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