PPT-Biomarkers & Pharmacogenomics

in CNS disorders Subbu Apparsundaram PhD CSO V ClinBio subbuvclinbiocom 1 862 485 7489 wwwvclinbiocom Sri Ramachandra University Porur Chennai India omics based prediction of drug response profiling. Raghu Kannan. “THE NEW . GOLD STANDARD. . IN . COMPANION . DIAGNOSTICS”. Introductory Slide. Current methods of detection. IHC: . Dako. –in accurate. PCR –amplifies . all . genes . FISH –works well; however, microscopic visualization of tumor regions is difficult. Worldwide Trends . 2014. What is a Biomarker?. Worldwide Trends. 2014. What is a Biomarker?. A biological marker, better known as a “biomarker”, is a characteristic . that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes or pharmacological responses to a therapeutic . James L. Cook, DVM, . PhD. Director, Comparative Orthopaedic Lab & . Mizzou. . BioJoint. Center. cookjl@health.missouri.edu. Osteoarthritis (OA): . Everyone’s Problem. Markets. Canine. 78M companion dogs in US (2015 APPA Survey). in CNS disorders. Subbu. . Apparsundaram. , PhD. CSO, V . ClinBio. subbu@vclinbio.com. 1 862 485 7489. www.vclinbio.com. Sri Ramachandra University. Porur. , Chennai, India. . omics. based prediction of drug response profiling. Expanding the Horizons. Basics of Biomarkers in RA. Biomarkers in ACR/EULAR RA Criteria. Discordance of Common RA Biomarkers. RA Practice Performance Project (RAPP). Framing the Discussion. Using ACPA Testing to Diagnose RA. actively. conducting . translational . medicine. research . to further our . understanding. of . cancer biology and to . identify. which . patient populations may . be. more . likely to derive benefit . in CNS disorders. Subbu. . Apparsundaram. , PhD. CSO, V . ClinBio. subbu@vclinbio.com. 1 862 485 7489. www.vclinbio.com. Sri Ramachandra University. Porur. , Chennai, India. . omics. based prediction of drug response profiling. Disease. NGAL and Cystatin C. COL SOHAIL SABIR. HOD NEPHROLOGY MILITARY HOSPITAL. HOD MEDICAL EDUCATION . ARMED . FORCES POSTGRADUATE MEDICAL INSTITUTE. Biomarker. characteristic . that is objectively measured and evaluated as an indicator of normal biological or pathogenic processes, or pharmacologic responses to a therapeutic intervention. Optimist. Department of Biochemistry, Molecular Biology and Biophysics. Institute on Biology of Aging and Metabolism. lniedern. @. umn.edu. Utility of mice in biomarker discovery. Strength . of mice. Authors: . Kieu Vu, John . Arend. , Nichole . Cadez. , Deb Darnell, Valerie . Somma. , . Randi Rycroft, . Loria. Pollack, . Paran. . Pordell. . Women’s Wellness Connection. BCCP (Triple negative breast cancer). PhUSE 2014 Paper SP06 Renuka Chinthapally, Cytel Statistical Software & Services Pvt. Ltd., Hyderabad, India ABSTRACT Biomarkers play an important role in the clinical development due to their ability Pragya Kumari. 1. , . Atanu. Bhattacharjee. 2. , Gajendra K. Vishwakarma. 1. 1. Indian Institute of Technology (ISM) Dhanbad, India, 826004. 2. Institute of . Acturial. . Sceience. and Data Analytics, UCSI University, Malaysia, 56000. Leyen. Vu, DO. Sept. 8. th. , 2018. WSU Cougar Health Services. WSU Athletics Team Physician. Objectives. Need for objective measures for concussion. Identify characteristics of ideal serum biomarkers for concussion. Nfl. =neurofilament light; PDGFR. . =. platelet-derived growth factor receptor beta. ; . PET=positron emission tomography; p-tau=phosphorylated tau; RT-. QuIC. =real-time quaking-induced conversion; SNAP-25=.