The relationship is characterized by best64257t lags highest and value for blood lead consistent with neurobehavioral damage in the 64257rst year of life and the peak age of offending for index crime burglary and violent crime The impact of blood le ID: 21143
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EnvironmentalResearch104(2007)315 336Understandinginternationalcrimetrends:ThelegacyofpreschoolleadexposureRickNevinNationalCenterforHealthyHousing,USAReceived12August2006;receivedinrevisedform20February2007;accepted23February2007Availableonline23April2007 E-mailaddress:ricknevin@verizon.net ofblood)cancauseseizuresanddeath,bloodleadoverg/dLisharmfultolearningandbehaviorandthereisnolowerbloodleadthresholdforIQlosses(USCentersforDiseaseControlandPrevention,1991Schwartz,1994Caneldetal.,2003).Thehalf-lifeofleadinbloodis30days,butpreschoolbloodleadoftenchangesslowlyduetocontinuingexposure,andthatleadburdenaccumulatesinteethandbones(WorldHealthOrganization,1995Needlemanetal.(2003)foundyouthswithhighboneleadaretwiceaslikelytobedelinquent,aftercontrollingforconfounders.Otherstudiesalsolinkpreschoolleadexposuretoaggressiveanddelinquentadolescentbehaviorandlatercriminalviolence(Denno,1990Needlemanetal.,Dietrichetal.,2001StreteskyandLynch(2001)foundUSAcountieswithhigh1990airlead,mostlyfromindustrialemissions,had1989 1991murderratesfourtimeshigherthancountieswithlowairlead,aftercontrollingfornineairpollutantsandsixsociologicalfactors.Thisstudylikelyreects1970sadditivepreschoolleadexposure,becauseifmurderweremuchaffectedbycontemporaneousairleadthenthehomicideratewouldhavefallenasgasolineleadandairleadfellover70%from1975 1984(USEnvironmentalProtectionAgency,1986).Most1990lead-emittingfacilitieswereinoperationfordecades,inareaswitholderhousingandsometrafc,so1989 1991murderrateslikelyreectedhigher1970sbloodleadwherechildrenhadadditiveexposuretoleadinpaintandgasolineandindustrialemissions.Nevin(2000)found1941 1975gasolineleaduseexplained90%ofthe1964 1998variationinUSAviolentcrime.Thebeststatistical-tlagof23-yearsisconsistentwithneuraldamageininfancyandpeakagesofviolentoffending.Nevinshowedabest-tlagof18yearsforgasolineleadversus1960 1998murders,and21yearsforpercapitapaintleaduseversus1900 1959murders.Thedifferenceinbest-tmurderlagsisconsistentwithwhenpaintandgasleadmostaffectedpreschoolleadexposure.Gasleadsettledoverafewweeksormonths,andheavilyleadedcirca-1900leadpaintdeterioratedviachalkingafter3years(SchwartzandPitcher,1989vanAlphen,19981.1.LeadexposurepathwaysandpopulationbloodleadtrendsElevatedbloodleadcanbeduetoleadpaintchipingestion,inhaledairlead,andotherpathways,butpaintandgasolinehadespeciallypervasiveeffectsduetoleadcontaminateddustingestedvianormalhand-to-mouthactivityaschildrencrawl.Averagedailyleadingestedby2-year-oldsexposedtodustcontaminatedbyinteriorleadpaintissimilartotheaveragefor2-year-oldsexposedtodustcontaminatedbysettledcityairlead,andaverage2-year-oldleadingestionviadustismanytimesaverageingestionviainhaledairlead,dietarylead(fromairleadsettledoncropsand/orleadsolderinfoodandbeveragecans),orotherpathways(USEnvironmentalProtectionAgency,1986LeadusedinpaintaccountedforalmostathirdoftotalUSAleadoutputfrom1900 1914,whentheUSAproducedover40%ofworldleadoutput(Nevin,2000USGeologicalSurvey,2006).ThehighUSApercapitauseofleadinearly-1900spaintcausedmoresevereUSAleadpainthazardsthroughoutthe20thCentury.TheleadshareofUSApaintpigmentsfellfromnear100%in1900to35%inthemid-1930s(MeyerandMitchell,1943),buttheUSAdidnotbanresidentialleadpaintuntil1978.Pre-1940and1940 1959homeseachaccountedforaboutathirdofUSAhomesintheearly-1980s,andabout80%ofpre-1940and46%of1940 1959homesstillhadsomeinteriorleadpaintin1999(USCensus,1977 2003Jacobsetal.,2002).Sincethe1980sUSAphaseoutofleadingasoline,preschoolbloodleadprevalenceover10g/dLhastrackedUSAtrendsintheprevalenceofhousingwithdusthazardscausedbyinteriorleadpaint(JacobsandNevin,2006Trendsinpreschoolbloodleadprevalenceover10areespeciallyaffectedbywidespreadexposuretoleaddusthazards,butpaintchipingestionisoftenafactorinsevereleadpoisoning.A1989 1990studyfoundthatchildrenwithX-rayevidenceofrecentpaintchipingestionhadaveragebloodleadof63g/dL(McElvaineetal.,1992PercapitauseofleadingasolinesurgedintheUSAafterWorldWarII,androseataslowerrateinnationswithlowerpercapitagasolineconsumption.Leademissionsfromurbantrafccausedgreaterleadexposureforcitychildrenbecause10%ofleademissionssettledwithin100moftheroadand55%within20km,howeveratmosphericemissionsalsoaffectedbloodleadinareaswithlittletrafc(OrganizationforEconomicCo-Opera-tionandDevelopment,1993).Nationaltrendsinaveragebloodleadandtheuseofleadingasolinewerehighlycorrelated,withmedianof0.94inGreece,Spain,SouthAfrica,Venezuela,Belgium,Sweden,Mexico,Finland,Canada,NewZealand,Italy,Switzerland,BritainandtheUSA(Thomasetal.,1999).Childrenexposedtoleadinpaintandgasolinehadagreaterriskofelevatedbloodleadbecauseleadingestionisadditive,butaveragebloodleadcloselytrackedgasolineleaduseduetoslowchangesinleadpaintexposureafterthe1930s.Leadexposurealsospannedawiderangeduetogasleadfalloutrelatedtocitysizeandroadproximity.USAcitieswithpopulationoveramillionhadearly-1960sambientairleadtwicethatincitiesof250,000toamillion,whichhadairlead40%higherthancitiesof100,000 250,000.AirleadbesideaheavilytrafckedCincinnatistreet(2150cars/horabout50,000cars/day)was15timesthecitysambientairleadUSPublicHealthService,1966,1965).Severeleadexposurewasanunrecognizedconsequenceoflocatingpublichousingbesidehighways.Forexample,ChicagoslongnarrowRobertTaylorHomesprojectthatopenedin1962wasallwithinabout400mof1963DanRyanexpresswaytrafcof150,000vehicles/day(AmericanHighwayUsersAlliance,2004Manychildrenhadadditive1950 1970exposuretocityairleadandseverelydeterioratedleadpaintincirca-1900ARTICLEINPRESSR.Nevin/EnvironmentalResearch104(2007)315336 slumhousing.Inthe1960smanyinnercityhospitalshadlargenumbersofcomatoseandconvulsingchildrenwithleadpoisoning,withfatalityratesof5 28%(Jackson,).Therewasextensiveslumdemolitionasurbanrenewalprojectsinexecutionroseseven-foldfrom1956 1966,butslumclearanceslowedinthelate-1960sUSDepartmentofHousingandUrbanDevelopment,).Publichousingcollocatedwithhighwaysonslumclearancelandalsocausedsevereairleadexposureaspercapitagasleadrose50%from1962to1970.Citybloodleadscreeningin1970showedabout25%ofyoungchildrentestedhadbloodleadover40g/dL.found95%of1970Censustractvariationinchildrenover40g/dLwasexplainedbythetractpopula-tionunderagesevenandprevalenceofdeterioratedordilapidatedhousing,butNewYorkCitychildrenoverg/dLrelativetosubstandardhousingprevalencewas20%higherthansmallercities,consistentwithhigherNewYorkCityairlead.The1976 1980NationalHealthandNutritionExam-inationSurvey(NHANES)revealedaverageUSApre-schoolbloodleadof15g/dL,andthe1988 1991NHANESshowedbloodleadfellsharplywiththeleadedgasphase-out(Pirkleetal.,1994).Percapitauseofleadingasolinepeakedlaterinmostnationsbutpercapitapaintleadusepeakedearlier,andleadpainthazardsraisedUSAelevatedbloodleadrisks.Australia1995averagepreschoolbloodleadwas50%abovethe1990USAaverage,but9%of1990USAchildrenversus7%of1995Australiachildrenwereover10g/dL(Pirkleetal.,1994AustralianInstituteofHealthandWelfare,1996).CanadianandUSAlate-1970saveragebloodleadweresimilarbut4%ofCanadianversus18%ofwhiteand52%ofblackUSAchildrenwereover20g/dL(RoyalSocietyofCanada,1986).In1960,blacksoccupied15%ofcentralcityhouseholdsand56%ofsubstandardcentralcityhousing,andthepercentofallcentralcityblacksinsubstandardhousingwas25%in1960and16%in1966(Kristof,1968Koebel,1996).Percapitagasleadfellfrom1956 1962buthitnewhighsfrom1966 1974,when62%ofblacksunderagesixlivedincentralcities,versus24%ofwhitechildren,withblacksconcentratedinolderhousing(USCensus,1960Averagebloodleadforblack2-year-oldsinChicagoandNewYorkCityfellbyabout30%from1970 1978,butthe1976 1980USAaverageforblackchildrenages6 36monthswasstill50%abovethewhiteaverage,andtheblackprevalenceover40g/dLwas800%higher(forToxicSubstancesandDiseaseRegistry,19881.2.Braingrowth,leadexposure,IQ,andbehaviorCriticalgrowthspurtsingrayandwhitematteroccurbeforeagetwo,whenelevatedmaternalandpreschoolbloodleadcausemanyneurologicaleffectsthatestablishabasisforimpairmentsinIQ,learning,andbehavior(etal.,1997LidskyandSchneider,2003Matsuzawaetal.,).Outcomesarealsoaffectedbyexposureseverity,duration,andtiming,andinteractionswithdietandsocioeconomicstatus(Bellinger,2004).BehaviorproblemscouldbeanindirecteffectofIQorthedirecteffectofbraindamageimpairingimpulsecontrol(Needlemanetal.,Gottfredson(1998)observesthatyouthswithIQof75 90areseventimesmorelikelytobeincarceratedthanthosewithIQof110 125,andstates:noothertraitorcircumstanceyetstudiedissodeeplyimplicatedinthenexusofbadsocialoutcomesaslowIQ.Thisperspective,however,doesnotaddresshowIQthatisstableafterchildhood(Neisseretal.,1996)mightrelatetoanage15 17propertycrimearrestratethataveragedninetimestheover-25ratefrom1970 2003.(BureauofJusticeStatistics,2004).Adifferentperspectiveisprovidedbymagneticresonanceimagingstudiesthatrevealasecondgraymattergrowthsurgejustbeforepuberty,predominat-inginthefrontallobe,theseatofexecutivefunctionsplanning,impulsecontrolandreasoning(InstituteofMentalHealth,2001Sowelletal.(1999)reportsscansatages12 16and23 30showingalargefrontallobedifferenceinmyelin,whichprogressivelyinsulatesandthickenswhitematterconnectionsbetweenneuroncellbodies.Bartzokisetal.(2001)reportsfrontallobewhitemattergrowthtoage50,asgraymatterdeclines,andexplains:Whatkeepsgrowingisthemyelin[which]affectsthespeedofthesignalsthattravelfromneurontoneuron[and]allowsyourbraintoworkinconcert;yourenotaspronetoimpulse(Foster,2001Bartzokisetal.(2001)attributesimpulsiveteenbehaviortoincompletemyelination,andlinksmyelindisruptiontodevelopmentaldisorders.Developmentaleffectsofleadexposureincludethedestructionofmyelinsheathsanddecreasedactivityofanenzymeintegraltomyelinsynthesis(LidskyandSchneider,).Moregenerally,Silbergeld(1992)observedthatleadexposureduringcriticalperiodsofvulnerabilitycancausepermanentbraindamage,butneurotransmissioneffectscouldbereversibleabsentcontinuousexposure.GraymatterdamagecausingpermanentIQloss,andneuro-transmissiondamagethataffectsbehavior,couldcauseanIQ crimecorrelationduetoseparateleadeffects.Age-relatedoffendingcouldbelinkedtoincompletemyelina-tionamongteenswithorwithoutpreschoolleadexposure,butcriminalbehaviorcouldbemorecommonandseverewithimpairedand/ordelayedmyelinationorotherneurotransmissiondamage.Whitemattergrowthtoage50suggeststhatlead-inducedneurotransmissiondisruptioncouldalsoaffectbehaviorwellbeyondadolescence,especiallyifmorecontinuousexposurecausesirreversibleInaSupremeCourtbriefopposingjuvenileexecutions,AmericanPsychologicalAssociation(2004)arguedthattheadolescentbrainhasnotreachedadultmaturity,particularlyinthefrontallobes,whichcontrolmaking.Thatbriefincludedagraphshowingviolentoffensesbuildsteeplyto18,beforestartingtodropoffasoffendingisoftenmoderatedoreliminatedbytheARTICLEINPRESSR.Nevin/EnvironmentalResearch104(2007)315336 individualinadulthood.Thatsamegraphalsorevealsage-specicarrestrateshiftsthattrackleadexposureandviolentcrimetrends[Fig.1].Youthsages16 22in1994wereallbornbeforetheearly-1980sfallingasolinelead,andtheage-16arrestratewas29%higherthantheage-22ratein1994,consistentwithcriminalbehaviorbeingmoderatedbychangesinfrontallobedevelopmentofadolescentsandyoungadults.The22-year-oldsin2001werealsobornbeforetheearly-1980sdeclineinleadexposure,butthe16-year-oldswereborninthemid-1980s,andthe2001age-16arrestratewas12%thantheage-22arrestrate.Thisstudyexaminesinternationaltrendsinpreschoolbloodlead,crimerates,andage-specicarrestsrates,totestwhethertherelationshipbetweenleadexposure,arrest,andcrimetrendsinFig.1isevidentacrossmanycrimecategoriesandacrossnationswithdivergentpreschoolbloodleadandcrimeratetrends.International,racial,andcitydifferencesinsevereleadpoisoningprevalencearealsocomparedwithsubsequentcontrastsinmurderratesandjuvenileviolence,withtheexpectationthatseverepre-schoolleadpoisoningcouldbelinkedtomoreviolentoffendingandespeciallytomurderrates.2.Methods2.1.ArrestrateandincarcerationtrendsUSAindexcrimesincludepropertycrimes(burglaryandtheft)andtheviolentcrimesofmurder,rape,robbery,andaggravatedassault(causinginjuryorwithalethalweapon).BritishindictableoffensesincludeUSAindexcrimesplusthreats,simpleassaultswithoutinjury,andpettytheftsbelowaUSAmonetarythresholdforlarceny.ThefollowingUSAandBritishdataareexaminedtohighlightpeakoffendingagesandtemporalshiftsinage-specicoffending:1.Britishage-speciccautionandconvictionrates(similartoUSAarrestrates)forindictableoffensesin1958versus1997(Taylor,1999CaliforniaDepartmentofJustice(2005)1960 2004juvenileandadultindexcrimearrestrates(age10 17arrestsper100,000ages10 17,andadultarrestsper100,000ages18 69).3.USA1970 2003age-specicpropertycrimearrestrates(BureauofJusticeStatistics,20044.USA1980 2001age-specicarrestratesforpropertyandviolentcrimes,and1980 2003juvenilearrestsbyrace(OfceofJuvenileJusticeandDelinquencyPrevention,20045.USAincarcerationbyage,andrecidivismtrends(HarrisonandBeck,BeckandHarrison,2001LanganandLevin,2002BureauofJusticeStatistics,1993,20012.2.PreschoolbloodleadandinternationalcrimetrendsRegressionanalysescompareinternationalcrimeratetrendswithestimatedpreschoolbloodleadtrends.Fig.2showsUSA1936 1999preschoolbloodleadestimatesanchoredbyNHANESdata,andestimatesforallagesforcomparisonwithearlierbloodleaddata(Thomasetal.,Pirkleetal.,1994USCentersforDiseaseControlandPrevention,1997,2000OrganizationforEconomicCo-OperationandDevelopment,).Theseestimatesreect1980 1988airlead,1946 1976reneryleaduse,and1936 1946roadgasolineuse(USEnvironmentalProtectionAgency,2001Nevin,2000;USCensus,1975).Early-1940sreneryleadincludesaviationfuelusedoverseas,sobloodleadestimatesdeclinewithwartimegasrationing(Chevron,2000Fig.3showsbloodleadestimatesforBritain,France,WestGermany,Finland,Italy,Canada,Australia,andNewZealand.Estimatesareanchoredbynation-specicbloodleaddatabecausethe55%ofgasleadthatsettledwithin20kilometersofroadscausedahigherratioofbloodleadtopercapitaleademissionsindenselypopulatednations(ARTICLEINPRESS Fig.1.USAviolentCrimeandLeadExposureTrendsandAge-SpecicViolentCrimeArrestRateShifts.Legend:Nevin(2000)foundthat1941 1975gasolineleaduseexplained90%ofthe1964 1998variationinUSAviolentcrime,wherethe23-yearlagisconsistentwithneurobeha-vioraleffectsofleadexposureininfancyandthetypicalageofviolentoffenders.Age-specicviolentcrimearrestrates(OfceofJuvenileJusticeandDelinquencyPrevention,2004)alsorevealthatpeakoffendingshiftedtoolderagesby2001,asthe1990sviolentcrimedeclinewasassociatedwithanespeciallysharpdeclineamongjuvenilesbornaftertheearly-1980sdeclineingaslead. Fig.2.USABloodLeadDataandTrendEstimates.Legend:Preschoolbloodleadestimatesreect1980 1988airlead,1946 1976reneryleaduse(seeFig.1),andpre-1946roadgasolineuse,anchoredbyNHANESdata(whichshowthat1976 1980preschoolbloodleadwashigherthanbloodleadforallages).Bloodleadestimatesforallagesarealsoshownforcomparisonwithotheravailable1956 1976surveydataonnational,largeurbanarea,andsmallcityandruralbloodleadlevels.R.Nevin/EnvironmentalResearch104(2007)315336 etal.,1999RoyalSocietyofCanada,1986OrganizationforEconomicCo-OperationandDevelopment,1993).Forsomenations,bloodleaddataforadults,olderchildren,and/orurbanpopulationswereadjustedbasedonNHANESratiosofpreschoolbloodleadtobloodleadforotherpopulationgroups(Pirkleetal.,1994).GasleademissiontrendswereavailableforCanada(RoyalSocietyofCanada,1986)andBritishtrendsreectpost-1969leademissionsandpre-1970petroluse(UKDepartmentofEnvironment,2004UKInstituteofPetroleum,1938 1970).EmissiontrendsforothernationsreectleadedgasuseandaverageleadperliterOrganizationforEconomicCo-OperationandDevelopment,1993InternationalEnergyAdministration,1960 1990OctelLtd,1969 1990UnitedNations,1950 1960).Datasupportestimatesfrom1936intheUSA,Canada,andBritain,andfrom1950intheothersixnations.Estimatesaresubjecttobloodleadsurveyrandomerrorandsomeestimationerror,butpotentialerrorissmallrelativetothelargetemporalchangesandinternationaldivergencesinpreschoolbloodlead[Figs.2and3Recordedcrimesper100,000residentsareexaminedforindexcrime,burglary,robbery,assault,rape,andmurder(BarclayandTavares,2003BureauofJusticeStatistics,2006Triggs,1997UKHomeOfce,2004StatisticsCanada,2005Mukherjee,etal.,1997AustralianInstituteofCriminology,1999 2006CouncilofEurope,2000,2003NewZealandPolice,2001,2005Interpol,2005).IndexcrimeforWestGermany,France,andItalyappeartobecomparabletoUSArates,whileBritain,Canada,Australia,Finland,andNewZealandincludeabroaderrangeofcrimes,resultinginhigherindexrates.USA,Canada,Australia,NewZealand,WestGermany,andpost-1968Britainburglaryratesarecomparable,asareUSA,Australia,Britain,Canada,NewZealand,andWestGermanyrobberyrates.Britainonlyrecordedpre-1969burglariesoveramonetarythreshold,andlowratesinFrance(notwell-documented)mayalsoreectathreshold.BritishwoundingiscomparabletoUSAaggravatedassault(LanganandFarrington,1998)andFrenchassaultdataappeartobecomparable.TheUSA,Britain,France,andFinlandreportrapeoffemale,andAustralia,NewZealand,andCanadareportviolentandsexualassaults.Singleandcombinednationregressionswererunwith5 45yearlagstoidentifybest-tlagsforeachcrime,withthehighestsignicance-value)forbloodleadandpercentofcrimeratevariationexplained(Regressionswerealsorunwithunemploymentratesfornationswithcomparabledata(BureauofLaborStatistics,2004).CombinednationARTICLEINPRESS Fig.3.InternationalPreschoolBloodLeadTrendEstimates.Legend:Internationalpreschoolbloodleadestimatesreectleademissiontrends,ancbynation-specicbloodleaddatabecausethe55%ofgasleadthatsettledwithin20kilometersofroadscausedahigherratioofbloodleadtopercapitaemissionsindenselypopulatednations.R.Nevin/EnvironmentalResearch104(2007)315336 resultsarereportedforbest-tlagswithandwithoutcountrydummies.Crimerecording,cultural,andothercountrydifferenceswilllowerthecombinednationindexcrimeregressionwithoutdummies,andtoalesserextentinothercombinednationregressionswithoutdummies.Toillustratebest-tlags,Fig.6acrosssingle-nationregressiontimelagsfordifferentcrimecategories,andFigs.7 11showcrimeversusbloodleadtrendgraphsforbest-tlags.Regressionresultsreectdatathrough2002,butsomegraphsincludedatathrough2004.Otherpotentialconfounderswereexcludedbecausepreliminaryanalysisshowednoimpactonlong-termcrimetrends.ThepercentofUSAviolentcrimeinvolvinggunswasfairlystablefrom1973 2004(BureauofJusticeStatistics,2005),asviolentcrimeroseandfellsharply.Only6%ofmurdersin1991and4%in2001werelinkedtodrugoffensesorbrawlsinuencedbynarcotics,andtherewaslittle1990schangeinthepercentofprisonerswhocommittedcrimestogetdrugmoney(Dorseyetal.,2005asmurderandothercrimesfellsharply.Internationalcrimetrendsareinconsistentwiththeoreticaleffectsofpolicepercapita,incarceration,anddemographictrends(BarclayandTavares,2003;USCensus,20042.3.Cross-sectionalregressionanalysisof19851994USAcentralcitymurderratesAseparateanalysiscomparesaverage1985 1994murderratesacrossUSAcitieswithdifferencesincirca-1970leadpaintpoisoningandairleadexposure.Childrenundersevenin1970wereinthehighmurderoffenseagebracketin1985 1994.LP%valueswereconstructedtoestimatethepercentofeachcitys1985 1994populationthathadseverechildhoodleadpaintpoisoningin1970.Citysizedummyvariableswereusedasindicatorsof1970airlead.Gilsinn(1972)usedpopulationundersevenanddeterioratedanddilapidatedhousingprevalencetoestimatethenumberofchildrenwithbloodleadover40g/dLineach1970metroarea.Theseestimatesapproximatethenumberofcentralcitychildrenover40g/dLbecausetherewaslittledeterioratedhousingin1970suburbs.Gilsinnsestimatesweredividedbyaverage1985 1994populationforthecorrespondingcitiestocalculateLP%.RegressionanalysiscomparesLP%withtheaverage1985 1994murderratesin124centralcity/cities,including11combinedcitymurderratescalculatedformetroareaswithmorethanonecentralcity.ThisregressiondoesnotreectairleadvariationsbecauseGilsinnsestimateswerebasedonhousingdata.Asecondregressioncomparescitymurderrateswithcitysizedummyvariablesasindicatorsof1970airlead,usingaverage1985 1994populationandmurderratesforthesame124city/cities.AthirdregressionwithLP%andcitysizedummiesexaminestheadditiveeffectofsevereleadpainthazardsandairlead.Theanalysisalsotestsfortheeffectoftheblackpercentofcitypopulation.Limitationsofthisanalysisincludecitiesinthesmallsizecategorywithairleadaffectedbylargecitiesinanothermetroarea(e.g.,NewarkandNewYork),childrenthatmovedbetweencitiesfrom1970to1985 94,and1970cityleadpaintpoisoningthatisoverstatedtotheextentthatsuburbsdidhavesomedeterioratedhousing(reectedinGilsinnsestimates).3.Results3.1.ArrestrateandincarcerationtrendsAge-14Britishmaleshadthehighestcautionandconvictionrateforindictableoffensesin1958,butpeakoffendingshiftedtoage18by1997.Theage-10offenseratefell70%from1958 1997,asage18 29offendingratesincreasedthreetove-fold.Malesages12 14in1958,bornasgasleadexposureroseafterWorldWarII,hadhigheroffendingratesthanolderteensbornbeforethatriseinleadexposure.By1997,offendingdeclinedrelativeto1958onlyformalesunder14,bornafterthemid-1980sfallinBritishgasleaduse,whileoffendingratesroseforolderteensandadultsbornoveryearsofrisinggasolineleaduse.USApercapitagasolineleadincreased400%from1945 55,andFig.4showstheCaliforniajuvenileindexcrimearrestratesurgedalmost300%from1965to1975.Theadultarrestrateroseatamuchslowerrate,whenmostadultswerebornbeforethe1950ssurgeingasolineleaduse.Thosetrendsreversedinthe1990swhenarrestratesfellfasterforjuveniles,bornafterairleadpeakedintheearly-1970s.In1975,Californiasjuvenileindexcrimearrestratewastwicetheadultrate,but2000 2004indexcrimearrestrateswerehigherforadults.(The1965 1975arrestratetrendspartlyreectinationincreasingthepercentoftheftsexceedingamonetarythreshold,revisedovertime,butthiswouldnotaffectjuvenilearrestratesrelativetoadults.)Propertycrimeaccountsforover90%ofindexcrimes.TheoverallUSApropertycrimeratewasaboutthesamein1970and2003,butthepropertycrimearrestrateforyouthsunderage15fell45%from1970 2003,theage15 17ratefell27%,theage18 24raterose8%,andthearrestrateforadultsover-24rose58%.The45%dropintheunder-15arrestratecomparesoffendersin1970bornnearthe1956interimpeakingasolineleadversusoffendersin2003bornaftertheearly-1980sfallingasolinelead.The58%increaseintheover-24arrestratecomparesadultsin1970mostlybornbefore1950versustheir2003counter-partsbornbefore1980.Fig.5compares1980 2001age-specicUSAarrestratesand1980 2003juvenilearrestratesbyrace.The1980 2001USApropertycrimedeclinewasledbya70%fallintheblackjuvenileburglaryarrestrate,whichfellmuchfasterthanthewhitejuvenilearrestratefrom1980 1988,narrowingtheracialdifference.Juvenileburglaryrateswerelittlechangedfrom1988 1994,butfellfurtherafter1994.The2003blackjuvenileburglaryarrestratewas43%belowthe1980whitejuvenilerate.PeakoffendingforARTICLEINPRESS Fig.4.CaliforniaAdultandJuvenileIndexCrimeArrestRates.Legend:CaliforniaDepartmentofJustice(2005)datashowthejuvenileindexcrimearrestraterosemuchfasterthantheadultarrestratefrom1965 1975,whenmostadultswerebornbeforethe1950sriseingasolineleaduse.Thosetrendsreversedinthe1990swhenarrestratesfellfasterforjuveniles,bornafterairleadpeakedintheearly-1970s.(Arresttrendsfrom1965 1975partlyreectinationincreasingthepercentoftheftsexceedingamonetarythreshold,revisedovertime,butthiswouldnotaffectjuvenilearrestratesrelativetoadults.)R.Nevin/EnvironmentalResearch104(2007)315336 robberyisafewyearsolderthanforpropetycrime,andthe42%fallintherobberyratefrom1980 2001wasentirelyduetosharplylowerarrestratesforjuvenilesandyoungadults,astheage35 44arrestraterose.Theblackjuvenilerobberyarrestratefellfrom1980 1988,narrowingtheracialdifference,buttheblackrateandracialdifferencerosefrom1988 1994beforefallingtonewlowsin2001 2003.Aggravatedassaultoffendingpeaksatanolderagethanrobberyandfallsmoreslowlywithage.Aggravatedassaultarrestsroseforallagesfrom1980 1994,buttheage40 44arrestratecontinuedtorisethrough2001.Blackjuvenilesrecordedthelargestrisefrom1985 1994,andthesharpestfallfrom1994 2001.Theunder-21homicidearrestratesoaredfrom1984 1994astheover-25ratedeclined,butthe1990shomicideratedeclinewasmainlyduetoasharpfallintheunder-21rate.Theblackjuvenilemurderarrestratedriftedlowerintheearly-1980sthenrosesharplybeforefallingtomulti-decadelows.Theracialdifferenceinjuvenilemurderarrestratespeakedin1994,butthe2003differencewasonlyaboutone-fourththeaverageracialdifferencefrom1980 1998.USAincarcerationtrendsechoarresttrends,asoffen-dersoverage34accountedforjust27%ofprisoncommitmentsin1993butaccountedfor40%in2001.TheoverallUSAincarcerationratechangedlittlefrom2000 2004,buttheage18 19maleincarcerationratefell30%andtheage20 34ratefell7%,asthemaleincarcerationraterose5%forages35 39,21%forages40 44,26%forages45 54,and41%forthoseover55.Over60%ofprisonersreleasedinboth1983and1994wererearrestedwithin3years,but35%ofthosereleasedin1983wereages18 25versus21%in1994.Combiningprisonerreleasetrendswithrecidivistoffendingratessuggeststhatprisonersreleasedintheprior3yearscommittedjust6%ofARTICLEINPRESS Fig.5.USAAge-SpecicArrestRatesandJuvenileArrestRatesbyRace.Legend:TheUSAcrimedeclinewasledbyasharpdeclineinoffendingbyjuveniles,andespeciallyblackjuveniles,asarrestrateschangedlittleforthoseoverage35.The1980sracialconvergenceinjuvenileburglaryarrestratescouldreecta1960sracialconvergenceinpreschoolbloodleadasslumdemolitionreducedleadpainthazards.Juvenileviolencealsofellfrom1980 butblackjuvenileviolencesurgedinthelate-1980sasblackjuvenileburglaryarrestschangedlittle.Thiscouldreectawiderearly-1970sblackpbloodleaddistributionwithmoresevereleadexposureespeciallyaffectingviolence(e.g.,amongyouthsraisedinpublichousingnearcirca-1970hR.Nevin/EnvironmentalResearch104(2007)315336 propertycrimesand11%ofviolentcrimesin1979versus28%ofpropertycrimesand35%ofviolentcrimesin2002.3.2.PreschoolbloodleadandinternationalcrimetrendregressionsThebest-ttimelagforindexcrimeversuspreschoolbloodleadis19yearsinaregressionwithcountrydummiescomparing309yearsofdataacrossninenations.Thesamebest-ttimelagisevidentinsingle-nationregressionswithandwithoutanunemploymentvariable.Table1regressionresultswitha19-yearlag,Fig.6graphsacrosslagsforeachnation,andFigs.7and8preschoolbloodleadtrendsversusindexcrimerateswitha19-yearlag.Bloodleadishighlysignicantincombinedandsingle-nationregressionswithandwithoutcountrydummies.Unemploymentissignicantinmostnationsbutitsinclusioninthemodelhasnosubstantiveeffectonthebloodleadcoefcientvalueorsignicance(-value),andlittleimpactoncrimeratevariationexplained().Addingunemploymentraisesfrom:80%to81%fortheUSA;87%to90%forCanada;72%to84%forFrance;andARTICLEINPRESS Table1Regressionsforpreschoolbloodleadvs.indexcrimewitha19-yearlagDependentvariableIndependentvariablesCoefcientStandarderrorIndexCrime9NationsCombinedIntercept3675.09311.8211.79.00010.165309PreschoolBloodLead176.2622.677.78IndexCrime9NationsCombinedIntercept2791.49236.9411.78.00010.774309WithCountyDummies(notshown)PreschoolBloodLead287.7114.3720.03AustraliaIntercept773.36910.820.850.40540.62823PreschoolBloodLead287.5848.315.95AustraliawithUnemploymentRateIntercept1690.66857.681.970.0627PreschoolBloodLead340.7846.157.39.00010.73223UnemploymentRate243.1487.222.790.0114BritainIntercept1665.60268.99.00010.95047PreschoolBloodLead740.5525.2229.37BritainwithUnemploymentRateIntercept1384.25243.47PreschoolBloodLead675.4131.4221.50.00010.96344UnemploymentRate75.9241.591.830.0752FinlandIntercept2312.83251.419.20.00010.88033PreschoolBloodLead589.4439.1815.05NewZealandIntercept2123.73580.893.660.00090.93633PreschoolBloodLead1053.8949.4221.32CanadaIntercept1624.66363.204.47.00010.86841PreschoolBloodLead440.0027.5215.99CanadawithUnemploymentRateIntercept863.50397.252.170.036PreschoolBloodLead336.4039.758.46.00010.89741UnemploymentRate280.7684.733.310.002USAIntercept1629.13241.546.74.00010.79843PreschoolBloodLead193.3015.2112.71USAwithUnemploymentRateIntercept1215.54364.513.330.0018PreschoolBloodLead181.8116.8410.80.00010.80843UnemploymentRate98.6165.831.500.142W.GermanyIntercept4012.72209.2319.18.00010.83422PreschoolBloodLead185.2518.4910.02W.GermanywithUnemploymentRateIntercept3750.86156.9823.89.00010.92322PreschoolBloodLead87.9124.573.580.002UnemploymentRate307.2565.894.660.0002ItalyIntercept830.33111.887.42.00010.92833PreschoolBloodLead148.977.4619.96ItalywithUnemploymentRateIntercept737.51153.034.82.00010.93033PreschoolBloodLead135.5816.778.09UnemploymentRate38.5643.210.890.3792FranceIntercept2386.69343.826.94.00010.72234PreschoolBloodLead175.7319.279.12FrancewithUnemploymentRateIntercept1889.03289.496.53PreschoolBloodLead28.1835.290.800.43060.83634UnemploymentRate367.6679.514.62:Regressionscombiningdataforninenationswererunforpreschoolbloodleadversusindexcrimewithtimelagsof5 45years,andthebest-tlag-valueforbloodlead)was19years.Recordingdifferenceslowerinthecombinedregressionwithoutcountrydummiesbutbloodleadisstillhighlysignicant.Bloodleadisalsosignicantandishighineachsingle-nationregressionwitha19-yearlag.UnemploymentissignicantbuthaslittleincrementaleffectonregressionR.Nevin/EnvironmentalResearch104(2007)315336 83%to92%forWestGermany.ItalyandBritainwithjustbloodleadis93%to95%andunemploymentisinsignicant.Graphsacrosstimelagsshow(andblood-value)peaksat18 21yearsinsixnations,at14 15yearsinWestGermany(22)andFrance(33)and26yearsinAustralia(Thebest-tlagforburglaryis18yearsinacombinedregressionforeightnations(229)withcountrydummies,andforvenations(169)withunemploy-mentdata(excludingburglarydataforFrancesuggestingamonetarythreshold).Table2showsbloodleadishighlysignicantincombinedandsingle-nationburglaryregres-Fig.6acrosstimelagsforeachnation,andFig.9graphsburglaryversusbloodleadwithan18-yearlag.Unemploymentissignicantbutitsinclusiononlyincreasesfrom65%to73%fortheUSA;78%to86%forCanada;85%to88%forBritain;and82%to92%forWestGermany.Australiais91%withjustbloodlead(unemploymentisinsignicant)andNewZealand86%withjustbloodlead.peaksatlagsof16 19yearsinsevennations,and21yearsinAustralia,basedondatathrough2002.Australiasburglaryratefellabout20%from2002 2004.Thebest-tlagforrobberyacrosssevennations220)is23years,andunemploymentisinsignicantacrosssixnations(Table3showsbloodleadwitha23-yearlagishighlysignicantincombinedandsingle-nationregressions.Fig.10graphsrobberyversusbloodleadwitha23-yearlag.AddingunemploymentraisessomewhatfortheUSAandCanadabutunemploymentisinsignicantorhasanunexpectedsigninothernations.Thebesttis20 21yearsinfournations,36yearsinFrance(14)and26 28inBritainandAustraliathrough2002.BritainandAustraliarobberyratesfellabout20%from2002 2004.Table4Fig.11showbloodleadwitha23-yearlagishighlysignicantinregressionsforaggravatedassault100)andviolentandsexualassault(67),andwitha24-yearlagforrape(113).Unemploymentisinsignif-icant.Thebest-tforaggravatedassaultis24yearsintheUSA(43),23inBritain(43),and29 33yearsinFrance(14).Thebesttlagforviolentandsexualassaultis24yearsinCanada(41),22inNewZealand15),and28 33inAustralia(11).Thebest-tforrapeis23yearsintheUSA(43),30inBritain(43),29inFrance(14),and27 33inFinland(13).Fig.6showsregressionforaggravatedassault,violentandsexualassault,andrapereachabsolutepeaksacrossarangeoflongerlagsinsingle-nationregressions.However,Table4-valuesareveryhighwiththe23 24yeartimelagforallsingle-nationregressionswithover14yearsofdataof79 94%).Table5showsbloodleadwithan18-yearARTICLEINPRESS Fig.6.acrossSingle-NationRegressionTimeLags.Legend:Single-nationregressionswererunwith5 45yearlagsforeachcrimecategoryversuspreschoolbloodlead,foreverynationwithavailabledata.Despitedivergentinternationalcrimeandbloodleadtrends,regression(andbloodlead-value)isnearitspeakineachnationattimelagsconsistentwithpeakoffendingagesforeachcrimecategory.R.Nevin/EnvironmentalResearch104(2007)315336 lagissignicantinthecombinednationmurderregression209)andunemploymentisinsignicant(178).Thebest-ttimelagis18 19yearsfortheUSA,NewZealand,andBritain,butCanadahasashorterbest-tandaveragepreschoolbloodleadisnotsignicantinmurderregressionsforAustraliaorWestGermany. Fig.7.PreschoolBloodLeadvs.NarrowlyDenedIndexCrimewitha19-YearLag.Legend:USAindexcrimeincludespropertycrimes(theftandburglary)andtheviolentcrimesofmurder,rape,robbery,andaggravatedassault(causinginjuryorwithalethalweapon).Nationswithcomparablecindexesallshowindexcrimeratestrackingpreschoolbloodleadtrendswitha19yearlag,despitedivergentcrimetrends.TheUSAindexcrimeratewas22%higherthantheFrenchrateand40%higherthanAustraliasratein1980,buttheUSAratewas39%belowtheFrenchrateand45%belowAustraliasratein2001. Fig.8.PreschoolBloodLeadvs.BroadlyDenedIndexCrimewitha19-YearLag.Legend:BroadlydenedindexcrimeratesincludeUSAindexcrimesplusthreats,assaultswithoutinjury,andtheftsbelowaUSAmonetarythreshold.Despiterecordingdifferencesanddivergentcrimetrends,broadldenedindexcrimeratesalsotrackbloodleadtrendswitha19-yearlag.R.Nevin/EnvironmentalResearch104(2007)315336 3.3.Cross-sectionalregressionanalysisof19851994USAcentralcitymurderratesTable6showstheregressionanalysesof1985 1994averagemurderratesacross124centralcity/cities.Theaverage1985 1994murderratewas33(per100,000)incentralcity/citieswithpopulationoveramillion,21incitiesof250,000toonemillion,and15incitiesof100 250thousand,andcitysizedummyvariablesaresignicantinasimpleregression,withof11.4%.LP%isalsohighlysignicantinaseparateregression,withof14%.WhenLP%andcitysizearebothincluded,regressionexceedsthevariationexplainedbyseparateregressions(11.4%+13.9%25.3%)andLP%andcitysizevariablesaremoresignicant(higher-values).Whenavariableisaddedforblackpercentofpopulation,citysizeisstillsignicantandLP%isnot(1.27),buttheLP%coefcientstillhastheexpectedsignandretainingLP%inthemodelincreasesto69%versus61%withjustthecitysizeandblackpercentvariables.ARTICLEINPRESS Table2Regressionsforpreschoolbloodleadvs.burglarywithan18-yearlagDependentvariableIndependentvariableCoefcientStandarderrorBurglary8NationsCombinedIntercept1072.11106.5310.06.00010.060229(UK,US,CAN,AUS,NZ,WG,FR,FIN)PreschoolBloodLead27.637.233.820.0002Burglary8NationsCombinedIntercept626.5073.098.57.00010.776229WithCountyDummies(notshown)PreschoolBloodLead83.334.5618.26Burglary5NationsCombinedIntercept586.49107.045.48.00010.299169(UK,US,CAN,AUS,WG)PreschoolBloodLead61.767.328.44Burglary5NationsCombinedIntercept714.8864.3211.11.00010.819169WithCountyDummies(notshown)PreschoolBloodLead75.814.0818.59Burglary5NationsCombinedIntercept397.6067.855.86.00010.869169WithCountyDummies(notshown)andUnemploymentRatePreschoolBloodLead53.914.4412.15UnemploymentRate78.919.967.92USABurglaryIntercept397.6784.114.73.00010.65343PreschoolBloodLead46.525.298.79USABurglarywithUnemploymentRateIntercept112.06115.390.970.3373PreschoolBloodLead38.855.307.32.00010.72743UnemploymentRate67.4720.593.280.0022BritainBurglaryIntercept51.84129.150.400.69080.84934PreschoolBloodLead141.0410.5213.41BritainBurglarywithUnemploymentRateIntercept147.83119.741.230.22630.88334PreschoolBloodLead121.7411.3810.70UnemploymentRate44.3314.723.010.0051CanadaBurglaryIntercept245.4075.373.260.00230.78141PreschoolBloodLead66.795.6611.79CanadaBurglarywithUnemploymentRateIntercept69.7672.040.970.3390.86041PreschoolBloodLead38.857.615.11UnemploymentRate72.3015.684.61AustraliaBurglaryIntercept544.87133.164.090.00030.91231PreschoolBloodLead132.387.6517.31AustraliaBurglarywithUnemploymentRateIntercept538.67133.184.040.0004PreschoolBloodLead121.9712.709.60.00010.91531UnemploymentRate24.4323.821.030.314W.GermanyBurglaryIntercept1403.1795.8614.64.00010.81920PreschoolBloodLead65.427.269.01W.GermanyBurglarywithUnemploymentRateIntercept1274.6269.7918.26.00010.92320PreschoolBloodLead31.588.593.670.0019UnemploymentRate120.4525.184.780.0002FranceBurglaryIntercept261.69105.512.480.02890.61414PreschoolBloodLead19.314.424.360.0009FranceBurglarywithUnemploymentRateIntercept272.37114.212.380.0362PreschoolBloodLead20.305.473.710.00340.61714UnemploymentRate3.339.960.330.7447FinlandBurglaryIntercept1065.13378.402.810.02020.28611PreschoolBloodLead78.6241.431.900.0902NewZealandBurglaryIntercept1153.40205.29.00010.86235PreschoolBloodLead254.3717.7314.35:Combined-nationregressionsforpreschoolbloodleadversusburglarywithtimelagsof5 45yearsshowedabest-tlagof18years.Bloodleadisalsosignicantandishighwithan18-yearlaginallsingle-nationregressionswith11.UnemploymentisstatisticallysignicantbuthaslittleincrementaleffectonregressionR.Nevin/EnvironmentalResearch104(2007)315336 4.Discussion4.1.ArrestrateandincarcerationtrendsThe1980sracialconvergenceinjuvenileburglaryratescouldreecta1960sracialconvergenceinpreschoolbloodleadduetoslumdemolitionanda1956 1962fallinpercapitagasleaduse,evenasurbansprawlspreadmoregasleademissionstopredominantlywhitesuburbs.A1960sbloodleadconvergenceisalsoconsistentwitharacialconvergenceinNationalAssessmentofEducationalProgress(NAEP)scoresreportedforthesamebirthcohort(Neisseretal.,1996).A2003blackjuvenileburglaryarrestratethatwaswellbelowthe1980whitejuvenilearrestrateisalsoconsistentwithlate-1980saverageblackpreschoolbloodleadwellbelowthe1970saverageforwhitechildren(Pirkleetal.,1994Juvenileviolencealsofellfrom1980 1984,butblackjuvenileviolencesurgedinthelate-1980sasblackNAEPscoresandjuvenileburglaryarrestschangedlittle.Thesetrendscouldreectawiderearly-1970sblackpreschoolbloodleaddistributionwithmoresevereexposureespe-ciallyaffectingviolence.Averageblackleadexposuremighthavechangedlittlefromthemid-1960stotheearly-1970sasdecliningleadpainthazardsoffsettheriseinambientairlead,butseverepoisoningprevalencelikelyroseamongblackchildrenlivingnearurbanhigh-ways.Astrongerassociationbetweensevereleadpoisoningandviolenceisalsoconsistentwithracialdifferencesinlate-1970sbloodleadandearly-1990sjuvenilearrestrates.Average1976 1980bloodleadforblackchildrenages6 36monthswas50%abovetheaverageforwhitechildren,butblacksweresixtimesmorelikelytohavebloodleadof30 39g/dLandeighttimesmorelikelytobeover40g/dL.Thosechildrenwerejuvenileswhenthe1990 1994blackjuvenileburglaryarrestratewas60%higherthanthewhiterate,buttheblackjuvenileviolentcrimearrestratewasvetimeshigherandtheblackjuvenilemurderratewaseighttimeshigher.ARTICLEINPRESS Fig.9.PreschoolBloodLeadvs.Burglarywithan18-YearLag.Legend:Thebest-tlagforpreschoolbloodleadversusburglaryis18yearsinacombined-nationregression.The1974USAburglaryratewas50%and98%higherthanratesinBritainandAustralia,respectively,andthe2002USAratewas56%and63%lowerthanratesinBritainandAustralia,butpreschoolbloodleadtrendspresagedburglaryratetrendswithan18-yearlagineachR.Nevin/EnvironmentalResearch104(2007)315336 Moftt(1993)distinguishesbetweenrelativelycommonAdolescence-Limited(AL)offendersandmoreviolentLife-Course-Persistent(LCP)offenderswhoaccountformostadultoffending.ShiftsinjuvenileindexcrimeandpropertycrimearrestratessuggestthatpreschoolbloodleadhasamajorimpactonALoffending.However,the2003USAage15 17propertycrimearrestratewasstillseventimestherateforadultsoverage24,showingALoffendingismorecommonacrossbirthcohortswithverydifferentpreschoolbloodlead.RisingarrestandincarcerationratesforolderadultssuggestthatLCPoffendingcouldalsoberelatedtopreschoolbloodlead.Braingrowthalsopresentsintriguingparallelswithlifetimeoffendinginonesampleofjuvenilecriminals:Offenseratesrosesharplyafterage10;propertycrimespeakedinadolescenceandfellalmost90%bytheearly-20s;andviolentoffendingpeakedintheearly-20sandfellafterage30withasharpdeclinebyage50evenamonghigh-ratechronicviolentoffenders(SampsonandLaub,2003Thesepatternsparallelbraindevelopmentfromthesurgeinoffendingandgraymattergrowthnearpuberty,throughgraymatterandoffendingpeaksaroundage20,tothepeakinwhitematterandasharpreductioninoffendingbyage50.ARTICLEINPRESS Table3Regressionsforpreschoolbloodleadvs.robberywitha23-yearlagDependentvariableIndependentvariableCoefcientStandarderrorRobbery7NationsCombinedIntercept11.968.061.480.1391(UK,US,CAN,AUS,NZ,WG,FR)PreschoolBloodLead7.880.5813.64.00010.461220Robbery7NationsCombinedIntercept9.415.591.680.09370.848220WithCountyDummies(notshown)PreschoolBloodLead7.420.3918.89Robbery6NationsCombinedIntercept1.568.420.190.8530.472190(UK,US,CAN,AUS,WG,FR)PreschoolBloodLead7.640.5912.97Robbery6NationsCombinedIntercept9.946.051.640.10210.830190WithCountyDummies(notshown)PreschoolBloodLead7.470.4317.41Robbery6NationsCombinedIntercept9.547.771.230.22110.830190WithCountyDummies(notshown)andUnemploymentRatePreschoolBloodLead7.490.5015.10UnemploymentRate0.091.140.080.9349USARobberyIntercept56.4513.234.270.00010.71543PreschoolBloodLead8.550.8410.14USARobberywithUnemploymentRateIntercept6.9920.430.340.7341PreschoolBloodLead7.630.839.20.00010.76743UnemploymentRate10.593.533.000.0046BritainRobberyIntercept65.959.30.00010.84343PreschoolBloodLead13.400.9014.83BritainRobberywithUnemploymentRateIntercept59.049.70PreschoolBloodLead14.371.0114.20.00010.85643UnemploymentRate2.551.331.910.0627CanadaRobberyIntercept26.205.814.51.00010.71241PreschoolBloodLead4.500.469.82CanadaRobberywithUnemploymentRateIntercept3.666.730.540.58990.81741PreschoolBloodLead2.840.515.55UnemploymentRate5.741.234.68AustraliaRobberyIntercept56.198.05.00010.89030PreschoolBloodLead7.470.5015.03AustraliaRobberywithUnemploymentRateIntercept41.118.20PreschoolBloodLead8.490.5216.27.00010.92230UnemploymentRate4.341.293.370.0023W.GermanyRobberyIntercept30.361.7717.19.00010.80219PreschoolBloodLead1.600.198.29W.GermanyRobberywithUnemploymentRateIntercept27.802.3811.69.00010.82819PreschoolBloodLead1.330.265.21UnemploymentRate1.020.661.540.1421FranceRobberyIntercept23.6282.890.280.78060.17614PreschoolBloodLead5.693.551.600.1351FranceRobberywithUnemploymentRateIntercept225.8969.683.240.0078PreschoolBloodLead8.402.323.620.0040.70014UnemploymentRate25.775.884.390.0011NewZealandRobberyIntercept36.364.12.00010.90830PreschoolBloodLead5.970.3616.66:Thebest-tlagforpreschoolbloodleadversusrobberyis23yearsinregressionscombiningdataforsevennations.Unemploymentisinsignicant.Bloodleadishighlysignicantandishighwitha23-yearlaginallsingle-nationregressionswithR.Nevin/EnvironmentalResearch104(2007)315336 4.2.PreschoolbloodleadandinternationalcrimetrendsItisstrikingthatpreschoolbloodleadishighlysignicantatbest-tlagsconsistentwithpeakoffendingagesforeachcrimecategory.Burglaryandotherpropertycrimearrestspeakatages15 20,andthebest-tforburglaryis18yearsincombinednationregressionsand16 19yearsinseparateregressionsfortheUSA,Canada,Britain,France,Finland,WestGermany,andNewZealand.Aggravatedassaultpeaksfromage18tothelate-20s,andthebest-tis22 24yearsforaggravatedassaultintheUSAandBritainandforviolentandsexualassaultinCanadaandNewZealand.Robberyarrestspeakfromage15tothemid-20s,andthebest-tlagis23yearsinacombinedregressionand20 21yearsfortheUSA,Canada,WestGermany,andNewZealand.Thebest-tlagforindexcrimeis18 21yearsintheUSA,Britain,Canada,Italy,Finland,andNewZealand.Somenationsshowlongerbest-tsforsomecrimes,butbloodleadisgenerallystillhighlysignicantattheinternationalbest-tforthatcategory.Althoughtimeseriescomparisonscanresultincoin-cidentalcorrelations,nonationshowsanycorrelationbetweenburglaryandbloodleadatlagsoflessthan10orover38yearsthebloodleadcoefcientinsuchregres-sionsisinsignicant.Nonationshowsanysignicantrelationshipbetweenrobberyorviolentandsexualassaultversusbloodleadwithalagoflessthan11years,betweenaggravatedassaultandbloodleadwithalagoflessthan14years,orbetweenrapeandbloodleadwithalagoflessthan13years.Changesinwhenunemploymentisaddedarealsoconsistentwithotherevidencethatunemploymenthasasubstantivelysmalleffectonpropertycrime(burglaryandmostindexcrime)andnoclearrelationshipwithviolence.ARTICLEINPRESS Fig.10.PreschoolBloodLeadvs.Robberywitha23-YearLag.Legend:Thebest-tlagforpreschoolbloodleadversusrobberyis23yearsinacombined-nationregression.TheCanadianrobberyratewasvetimestherateinBritainin1962,butthe2002CanadianratewaslessthanhalftherateiR.Nevin/EnvironmentalResearch104(2007)315336 Theveryhighsignicanceofbloodleadatlagsconsistentwithpeakoffendingagesisespeciallystrikinginlightofdivergentcrimeratetrends.Canadasindexcrimeratewas60%higherthantherateinBritainintheearly-1970s,but20%lowerin2001.TheUSAindexratewas22%higherthantheFrenchrateand40%higherthanAustraliasratein1980,buttheUSAratewas39%belowtheFrenchrateand45%belowAustraliasratein2001.The1974USAburglaryratewas50%and98%higherthanratesinBritainandAustralia,respectively,butthe2002USAratewas56%and63%lowerthanratesinBritainandAustralia.TheCanadianrobberyratewasvetimestherateinBritainin1962,butthe2002CanadianratewaslessthanhalftherateinBritain.The1960USAaggravatedassaultratewasalmostthreetimestherateinBritain,butthe2002USAratewashalftherateinBritain.The1960USAraperatewaseighttimestheBritishrate,butthe2002USAraperatewasjust50%higherthantheBritishrate.Indexcrimerecordingdifferencesresultinlower(16.5%)inthecombined-nationindexcrimeregressionwithoutcountrydummies,butthesedifferencesalsomakethesignicanceofbloodleadinthisregressionmoreremarkable.Thehigh(63 93%)ineachsingle-nationindexcrimeregressionwitha19-yearlagalsosuggeststhatbloodleadaffectsmanytypesofcriminalbehaviorincludingsimpleassaultsandpettythefts.Moreuniformrecordingofburglaryandrobberyresultinofalmost30%inthe5-nationburglaryregressionwithoutcountrydummies,andof46%inthe7-nationrobberyregressionwithoutcountrydummies.4.3.Cross-sectionalanalysisof19851994USAcentralcitymurderratesItiswellknownthat1980 1994USAmurderratesmainlyreectedtrendsinlargecities,butairleadandgasolineleadtrendscanexplainwhythelargestUSAcitieshadsuchhighmurderrates.Citieswithpopulationoveramillionhad1960sairleadabouttwicethelevelincitiesof250,000toamillion,whichhadairlead40%higherthancitiesof100 250thousand.Average1985 1994murderratesincity/citiesoveramillionwerethen57%higherthanincity/citiesof250,000toamillion,whichhadaverageARTICLEINPRESS Table4Regressionsforpreschoolbloodleadvs.aggravatedassaultandviolent&sexualassaultwitha23-yearlag,andvs.rapewitha24-yearlagDependentvariableIndependentvariableCoefcientStandarderrorAgAssault3NationsCombinedIntercept99.0525.793.840.0002(UK,US,FR)PreschoolBloodLead9.991.715.84.00010.258100AgAssault3NationsCombinedIntercept18.9214.571.300.1974WithCountyDummies(notshown)PreschoolBloodLead22.251.2018.54.00010.803100USAAgAssaultIntercept20.6313.201.560.1257PreschoolBloodLead17.190.8420.44.00010.91143BritainAgAssaultIntercept116.8115.14PreschoolBloodLead36.621.4724.89.00010.93843FranceAgAssaultIntercept43.4376.270.570.5796PreschoolBloodLead8.013.272.450.03040.33414V&SAssault3NationsCombinedIntercept257.0757.844.44(CAN,AUS,NZ)PreschoolBloodLead32.283.998.08.00010.50167V&SAssault3NationsCombinedIntercept73.3137.241.970.0534WithCountyDummies(notshown)PreschoolBloodLead46.662.9315.92.00010.84467CanadaV&SAssaultIntercept96.1926.133.680.0007PreschoolBloodLead44.692.0621.69.00010.92341NewZealandV&SAssaultIntercept1510.00341.194.430.0007PreschoolBloodLead178.8425.407.04.00010.79215AustraliaV&SAssaultIntercept842.56480.611.750.1135PreschoolBloodLead75.2523.103.260.00990.54111Rape4NationsCombinedIntercept0.142.040.070.9461(UK,USA,FR,FIN)PreschoolBloodLead1.230.148.63.00010.402113Rape4NationsCombinedIntercept7.510.68WithCountyDummies(notshown)PreschoolBloodLead1.390.0624.72.00010.951113USARapeIntercept6.301.284.94PreschoolBloodLead1.570.0819.11.00010.89943BritainRapeIntercept5.490.82PreschoolBloodLead1.170.0814.49.00010.83743FranceRapeIntercept3.352.861.170.2648PreschoolBloodLead0.710.125.71.00010.73114FinlandRapeIntercept3.391.831.850.0915PreschoolBloodLead0.620.212.880.0150.42913:Incombinednationregressions,thebest-tlagforaggravatedassaultandforviolentandsexualassaultis23years,andthebesttforrapeis24years.Bloodleadisalsosignicantwitha23/24-yearlaginallsingle-nationregressions.Unemploymentisnotsignicantinassaultandraperegressions.R.Nevin/EnvironmentalResearch104(2007)315336 1985 1994murderrates40%higherthancitiesof100 250thousand.LP%,reecting1970leadpaintpoisoning,isalsohighlysignicantinasimpleregression.TheregressionforcitysizeandLP%yieldshigherstatisticalsignicance-values)andexplanatorypower()thanseparatesimpleregressions,consistentwitheffectsofgasolinelead(citysize)andleadpainthazards(LP%),plustheadditiveeffectofpaintandgasolinelead(notcapturedbyseparateregressionsforcitysizeandLP%).AnassociationbetweenmurderandmoresevereleadexposurecouldexplainwhyWestGermanandAustralianbloodleadtrendsshownostatisticalrelationshipwithrecentmurdertrends.WestGermanylikelyhadalowprevalenceofseverelyelevatedbloodleadduetodestruc-tionofoldhousing(withleadpaint)duringWorldWarII.Australiadataalsoshowarelativelylow1990sprevalenceofelevatedbloodleadevenwhenaveragepreschoolbloodleadwasrelativelyhigh.Australianmurderrates(andincarceration)didfallfrom1900throughthe1940sfollowedbyalongslowrisesincethe1940s(Graycar,),consistentwithadeclineinpaintleadexposurefollowedbyrisinggasolineleadexposure.USAleadpaintpoisoningmusthavedeclinedasseverelydeterioratedslumsweredemolishedfromthemid-1950sthroughthe1960s,buttheUSAmurderrateuctuatedfrom8to10per100,000from1971 1994.Therefore,thehypothesisthatmurderisespeciallyassociatedwithsevereexposureimpliesthatseveregasolineexposureincreasedasseverepainthazardsdeclined.Ruralandcitysizemurdertrendsareconsistentwiththatshift.Theruralshareofthepopulationwas26%in1980andin1990buttheruralshareofUSAmurdersfellfrom14%in1976to7%in1994,andtotalruralmurdersfell44%from1980 1994.Thatmurderdeclineisconsistentwithafallinruralpaintleadexposurefrom1940 1970,whentheaveragefarmhomewasabout35yearsold(USCensus,1975),sohalfof1940farmhomeswerebuiltbefore1905withhighlyleadedinteriorpaint,whereashalfof1970farmhomeswerebuiltafter1935wheninteriorleadpaintwasfarlesscommon.Urbanairleadroseasleadpaintexposurefell,anda1980smurderdeclineoutsideofcitiesover100,000wasoffsetbyasharpriseinlargecitieswiththeworst1960sairlead.From1981 1991,USAmurderratesrose3%incitiesof100 500thousand,9%incitiesof500,000to1million,and26%incitiesoveramillion.The1980sphase-outofgasleadleftlittleairleaddifferencebycitysize,andaverage2000 2002murderrateswere14.7(per100,000)incitiesoveramillion,14.6incitiesof500,000toamillion,15.0incitiesof250 500thousand,and9.5incitiesof100 250thousand(FoxandZawitz,2004ARTICLEINPRESS Fig.11.PreschoolBloodLeadvs.Assaultwitha23-YearLag(AggravatedAssaultorViolent&SexualAssault).Legend:Incombinednationregressionsthebest-tlagversusbloodleadis23yearsforaggravatedassaultandforviolentandsexualassault.The1960USAaggravatedassaultratewasalmostthreetimestheBritishrate,andthe2002USAratewashalftherateinBritain,yetthebest-tlagis22 24yearsforaggravatedassaultinsingle-natiregressionsforboththeUSAandBritain.R.Nevin/EnvironmentalResearch104(2007)315336 Chicagomurdertrendsalsoprovideanecdotalevidenceofarisingpercentofmurdersrelatedtoseveregasolineleadexposure.In1980,18yearsafterits1962openingbesidetheDanRyanexpressway,RobertTaylorHomesaccountedfor0.5%ofChicagospopulationand11%ofChicagomurders(ONeill,1997Hagedorn(2004)expresswaysandhousingprojectsconcentratedChicagohomicidesinBlackareas,andillustratesthispointbymappinghighwaysagainst1965murderrates,presentedbesideapictureofRobertTaylorHomesandtheDanRyan.Butleadpaintpoisoninginlate-1940sslumsisalsoconsistentwithmurdersnearhighwaysin1965,whenchildrenfromthoseslumswereyouthslivingnearhigh-waysbuiltonslumclearanceland.HighwayairleadthenpeakedabouttwodecadesbeforeChicagos1992murderratepeak.Hagedornnotes:MurderinChicagoisnowmorecommoninthefarwesternandsouthernareasofthecity.Why?Hisspatialanalysisappearstoshow1992murderstrackingexpresswaystothewestandtheDanRyansouth,wherethe50%riseinUSApercapitagasolineleadusefrom1962 1970spreadleadpoisoningwellbeyondtheinnercity.4.4.Temporaltrends,cross-sectionalconfounders,andothercrimetheoriesrevisitedNeedlemanetal.(2003)foundthatsocialfactors,includingraceandsingle-parents,raiseddelinquencyriskforyouthswithlowerbonelead.Preschoolleadexposureishighlycorrelatedwithsocialfactorsbecausepoorchildrenaremorelikelytoliveinolderhousingwithdeterioratedpaint,andblackchildrenwereconcentratedincitieswithhigherairlead.Socialfactorscouldconstituteindependentoffendingrisksforthosewithnopreschoolleadexposure,and/orinteractwithleadexposuretoincreaseoffendingrisk,buttemporaltrendssuggestanyindependentsocialfactoreffectissmallrelativetotheleadeffect.Thejuvenilearrestratesoaredinthe1960s,trackingthesurgeingasleadafterWorldWarII,despitealarge1960sdeclineinthepercentofchildreninpoverty.Thatriseinjuvenileoffendingcoincidedwitha1960sriseintheunwedteenbirthrate,andthe1990sdeclineinjuvenilearrestscoincidedwithafallingunwedteenbirthrate.HigheroffendingduetosingleparentswouldbeconsistentwithjuvenileoffendingthatlaggedtheunwedbirthtrendbyARTICLEINPRESS Table5Regressionsformurdervs.preschoolbloodleadwithan18-yearlagDependentvariableIndependentvariableCoefcientStandarderrorMurder6NationsCombinedIntercept0.5230.4681.120.265(UK,US,CAN,AUS,NZ,WG)PreschoolBloodLead0.1920.0345.73.00010.137209Rape6NationsCombinedIntercept0.0520.1600.320.7471WithCountyDummies(notshown)PreschoolBloodLead0.1140.01110.22.00010.925209USAMurderIntercept3.8270.4019.54PreschoolBloodLead0.2610.02510.34.00010.72343USAMurderwithUnemploymentRateIntercept2.9540.5924.99PreschoolBloodLead0.2380.0278.73.00010.74743UnemploymentRate0.2060.1061.950.0582BritainMurderIntercept0.4580.0647.21PreschoolBloodLead0.0650.00611.47.00010.76343BritainMurderwithUnemploymentRateIntercept0.4610.0647.17PreschoolBloodLead0.0690.0088.16.00010.76443UnemploymentRate0.0060.0110.560.5779CanadaMurderIntercept1.2800.1866.90PreschoolBloodLead0.0560.0144.030.00030.29441CanadaMurderwithUnemploymentRateIntercept1.0100.2054.92PreschoolBloodLead0.0130.0220.610.54250.39241UnemploymentRate0.1110.0452.480.0177AustraliaMurderIntercept2.2900.15914.44PreschoolBloodLead0.0200.0092.210.0350.14431AustraliaMurderwithUnemploymentRateIntercept2.3020.15414.98PreschoolBloodLead0.0400.0152.740.01050.22631UnemploymentRate0.0470.0271.720.0973WestGermanMurderIntercept1.3610.05226.27PreschoolBloodLead0.0020.0040.630.53660.02220WestGermanMurderwithUnemploymentRateIntercept1.3070.04727.93PreschoolBloodLead0.0120.0062.030.05880.35820UnemploymentRate0.0500.0172.980.0084NewZealandMurderIntercept0.5830.5051.150.2575PreschoolBloodLead0.2790.0426.63.00010.60331:Thebest-tlagformurderis18yearsinregressionscombiningdataacrosssixnations.Unemploymentisinsignicant.BloodleadisnotsignicantorhasanunexpectedsigninmurderregressionsforAustraliaandWestGermany,butbloodleadishighlysignicantinothersingle-nationregressionsformurderwithan18-yearlag.R.Nevin/EnvironmentalResearch104(2007)315336 12 17years,aschildrenraisedbysinglemothersbecameteenagers.Thecoincidentriseandfallofunwedbirthratesandjuvenileoffendingisinconsistentwiththetime-precedenceindicatorofcausation.Nevin(2000)showedage-specicunwedpregnancyratestrackUSAgasleadtrendswithtimelagsconsistentwithmothersageandleadexposureintherstyearoflife.Cross-sectionalstudiesthatlinkcriminaloffendingtosingleparentscouldreectseparateeffectsofpreschoolleadexposureondifferenttypesofimpulsivebehavior,acrossfamilygenerations.Socialtrendscannotexplainwhythe1990shomicidedeclinewassopronouncedamongjuvenileoffenders,andespeciallyblackjuveniles,butbloodleadtrendscan.Bloodleadprevalenceover30g/dLamongwhiteUSAchildrenfellfrom2%in1976 1980tolessthan0.5%in1988 1991,asprevalenceover30g/dLamongblackchildrenplum-metedfrom12%tobelow1%.Thewhitejuvenilemurderarrestratethenfellfrom6.4to2.1from1993 2003,astheblackjuvenileratefellfrom58.6to9.7.That83%fallintheblackjuvenilemurderarrestrateoccurredwithjust36%ofblackchildrenlivingintwo-parentfamiliesin1993,andin2003.Age-specicarrestratesrelatedtopreschoolbloodleadcanexplainwhycrimepredictionsbasedon1990sdemographictrendsprovedinaccurate,andwhyincarcera-tionandcrimebothrosepriorto1990asincreasedoffendingbyjuvenilesandyoungadultsmorethanoffsettheincapacitationofolderoffenders.Gunuseofferslittleinsightintooverallcrimetrends,butgunhomicidesdidaccountformostofthe1973 2002USAmurderratevariation.Thesetrendsarenotinconsistentwiththehypothesisthatmurderisespeciallyaffectedbysevereleadpoisoning,butsuggestanespeciallylethalinteractionbetweengunaccessandsevereneurobehavioraldamage.Thiscouldexplainwhyruralmurdersfellafter1980despiteeasyruralaccesstoguns.The1990sfallinblackjuvenilemurderarrestscoincidedwithafallinblackyouthscarryingguns,butbloodleadtrendscouldexplainwhysomanyblackyouthsstoppedcarryinggunsatthesametime.Theblackpercentofcitypopulationappearstoexplainmuchofthecross-sectionalvariationinaverage1985 1994USAcentralcitymurderrates,butthe1990smurderratedeclinewasalsoledbyasharpdeclineinoffendingbyblacksincentralcities.NewYorkCitysracialcomposition(28%black)alsoprovidesnoinsightintotheespeciallystrikingdeclineinthatcitysmurderratefrom31(per100,000population)in1990to7in2004.The2004murderratewas20inDallas(27%black),14inPhoenix(6%black),13inHouston(26%black),13inLosAngeles(12%black),and8inSanAntonio(7%black).NewYorkCityhadextensiveslumdemolitionandreducedincin-eratorleademissionsinthe1960s,andbannedleadpaintin1960,resultinginalargereductioninleadpoisoning.NewYorkCitychildrenover60g/dLfellfrom2694in1970to494in1974,andchildrenover40g/dLfellfrom1595in1975to976in1980.NewYorkCityandSt.Louisbothreportedabout1200childrenperyearwithbloodleadARTICLEINPRESS Table6USAcentralcitymurderrateregressionsDependentvariableIndependentvariableCoefcientStandarderrorCentralCityMurderRateIntercept13.64011.45419.38.00010.1141241million14.75604.11273.590.0005250,000 1million5.31372.16242.460.0154CentralCityMurderRateIntercept8.69472.11644.11.00010.139124LP%0.00780.00184.44CentralCityMurderRateIntercept2.04442.26290.900.36810.3291241million19.49113.67545.30250,000 1million7.07111.91133.700.0003LP%0.01000.00166.19CentralCityMurderRateIntercept6.36351.13845.59.00010.6081241million16.71512.75386.07250,000 1million4.95101.44583.420.0008Black%ofPopulation0.03090.002512.28CentralCityMurderRateIntercept1.40881.55350.910.36630.6881241million12.85522.58504.97250,000 1million4.16941.33473.120.0022LP%0.00170.00131.270.207Black%Population60.37295.177911.66:Theseregressionscompareaverage1985 1994murderratesacrossUSAcitieswithdifferencesincirca-1970childhoodleadpaintpoisoningandairleadexposure.Preschoolchildrenin1970wereinthehighmurderoffenseagebracketin1985 1994.TheLP%variablemeasuresthepercentofeacitys1985 1994populationthathadseverechildhoodleadpaintpoisoningin1970.Citysizedummieswereusedasindicatorsof1970airlead.CitysiandLP%arebothsignicantinsimpleregressions.WhenLP%andcitysizearebothincluded,regression(32.9%)exceedsthevariationexplainedbyseparateregressions(11.4%+13.9%25.3%)andLP%andcitysizearemoresignicant(higher-values),reectingtheadditiveeffectofpaintandgasolineleadnotcapturedbyseparateregressionsforcitysizeandLP%.Whenavariableisaddedforblackpercentofpopulation,citysizeisstillsignicantandLP%isnot(1.27),buttheLP%coefcientstillhastheexpectedsignandretainingLP%inthemodelincreasesto69%.R.Nevin/EnvironmentalResearch104(2007)315336 over30g/dLfrom1981 1985,whenNewYorkspopula-tionwas16timeslarger.Chicago,Detroit,Baltimore,Philadelphia,andSt.Louisreport3 4%ofchildrentestedin1998 1999hadbloodleadover20g/dL,butNewYorkCityprevalenceover20g/dLwasjust0.4%(NewYorkCityDepartmentofHealth,2002MissouriDepartmentofHealthandSeniorServices,2004Meyeretal.,2003CentersforDiseaseControlandPrevention,2005landDepartmentoftheEnvironment,2004DonohueandLevitts(2001)theorylinkingearly-1970sabortionlegalizationtothe1990sUSAcrimedeclinehighlightsthelagbetweenbirthandpeakoffendingages.USApreschoolbloodleadpeakedintheearly-1970s,andbloodleadtrendscanexplainearlierUSAandinterna-tionalcrimetrends.DonohueandLevittcreditearlyabortionlegalizationwithearlycrimedeclinesinNewYorkandCalifornia,butstate-wideabortionlegalizationdidnotpresageanearlystate-wideNewYorkcrimedecline.ThatearlycrimedeclinewasevidentonlyinNewYorkCitywheretherewasapronounceddeclineinleadpoisoning(NewYorkState,1999,2004).Californiaalsolimitedgasleadperliterto0.26gin1977and0.18gin1978,beforeanationallimitof0.29gin1983(OctelLtd,1969 1990).Californiapercapita(leaded)gasolineusewasalso30%higherthantherestoftheUSAin1950,20%higheroverthe1950s,and10%higherinthe1960s.Californiasviolentcrimeratewasthen40%higherthantherestoftheUSAfrom1960 1990,anditsburglaryratewas75%higherinthe1960s,55%higherinthe1970s,and27%higherinthe1980s(FederalHighwayAdministration,2003;USCensus,1975BureauofJusticeStatistics,20065.ConclusionsThisanalysisaddstomountingevidencethatpreschoolleadexposureaffectstheriskofcriminalbehaviorlaterinlife.Arrestrateshiftsandinternationaltrendssuggestthatpreschoolbloodleadespeciallyaffectsjuvenileoffendingandrelatedtrendsinindexcrime(mainlypropertycrime)andburglary.Violentcrimetrendsandshiftstohigheradultarrestratessuggestbloodleadalsoaffectsviolentandrepeatoffending.Itislikelythatpolicerecordedcrimeandarrestratetrendsexaminedherealsounderstatetheeffectthatleadhadonthe1990sUSAcrimedecline,becausecrimesurveydatashowanevensteeper1990sviolentcrimedecline,asalargershareofcrimeswerereportedtoandrecordedbypolice,andviolentcrimearrestsfelllessthanpolicerecordedviolentcrimes,asalargerpercentofreportedcrimeswereclearedbyarrest(BureauofJusticeStatistics,2007Thehypothesisthatmurderratesareespeciallyaffectedbysevereleadpoisoningisconsistentwithinternationalandracialcontrastsandacross-sectionalanalysisofaverage1985 1994USAcitymurderrates.Whetherotheroffendingrisksareespeciallyrelatedtoabloodleadthresholdisnotknown.Nothresholdissuggestedbyrisingcrimethattracesbacktoaveragepreschoolbloodleadof5g/dLorlessinnationswhereseverepoisoningwasrare.USAjuvenilearrestratesfallingthrough2003alsoshownoevidenceofathresholdrelatedtohistoricallylowlate-1980sbloodlead.OtherresearchlinkspreschoolleadexposuretoawidevarietyofadverseneurodevelopmentaleffectsincludingADHD,otherbehavioralproblems,andIQlosses.Age-specicarrestratessuggestIQmayhaveonlyalimitedindirectrelationshipwithcrime,butevidenceofnolowerthresholdforlead-inducedIQeffectswarnsthatthereisnolowerthresholdforneuraldamage,andnoreasontoassumethatlowerbloodleadaffectsIQandnotothermanifestationsofneuraldamage,includingcriminalbehavior.Furtherresearchisneededtospecifythemechanismsbywhichbloodleadaffectsbehavior,andhowbloodleadinteractswithotherriskfactors,butpolicyimplicationsofthisstudyandrelatedresearchareclear:Theassociationbetweencrimeandpreschoolbloodleadshouldlendurgencytoglobaleffortstoeliminatepreschoolleadexposure.Thisanalysishasfocusedongasolineandpaintleadasdeterminantsoftrendsinaveragepreschoolbloodleadandsevereleadpoisoningprevalence,butchildrenandpregnantwomenarealsoexposedtooccupationalandsecondaryleadexposure(leaddustbroughthomeonworkclothes),leadindrinkingwaterfromoldwatermainsandservicelineconnectors,industrialleademissions,lead-contaminatedtoxicwastesites,lead-glazedceramics,andhomeremediesandcosmeticsinsomenations(RapuanoandFlorini,1994Actionisneededtoaddressalltheserisks.Over30nationsstilluseleadedgasoline,andaplannedglobalphase-outby2008mustbeaccelerated(UnitedNations,2005LeadpainthazardsarebyfarthegreatestremainingUSAleadexposurerisk.Theactionsneededtoeliminatesuchhazardsarewellknown,andhazardreductioncostsaremorethanoffsetbyhigheraveragelifetimeearningsresultingfromavoidedcognitivelosses(PresidentsTaskForceonEnvironmentalHealthRisksandSafetyRiskstoChildren,2000USDepartmentofHousingandUrbanDevelopment,1999).Asimplewindowreplacementstrat-egycanalsoyieldlong-termleadpainthazardreductionplusenergysavingsfromhigh-efciencywindowsthatexceedwindowreplacementcosts(JacobsandNevin,2006NevinandJacobs,2006Nevinetal.,1999).Avoidedcrimebenetsfurtherincreasenetbenets,andthisanalysissuggeststhatfurtherreductionsinpreschoolleadexposurewillyieldfurtherreductionsincrime.AcknowledgmentsTheauthoracknowledgesthevaluableregressionanaly-siscontributionsofArtemGonopolskiy.ReferencesAgencyforToxicSubstancesandDiseaseRegistry,1988.TheNatureandExtentofLeadPoisoninginChildrenintheUnitedStates.USDepartmentofHealthandHumanServices.ARTICLEINPRESSR.Nevin/EnvironmentalResearch104(2007)315336 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