PPT-Genetic Findings in Familial Gastrointestinal Cancers

Zsofia K Stadler MD Clinical Genetics amp GI Oncology Services Memorial SloanKettering Cancer Center March 27 2015 The heritable fraction of many human cancers is high Sweden Denmark Finland registry of 44788 twin pairs. Hypercholesterolaemia. . N. ew local pathways. Dr Peter Carey. Consultant in Diabetes and Endocrinology. Sunderland Royal Hospital . . Lipid Specialists Advisory Group. North East Cardiovascular Network. in familial breast cancer . . can . lie deep in . family . tree. San Ming . Wang. University of Nebraska Medical Center. Genetically defined breast cancer. Sporadic . B. reast . C. ancer . caused by . Serrated Polyposis Joanne Young Familial Cancer Laboratory QIMR Australia Serrated Polyposis • Group of conditions characterised by multiple serrated polyps (5 - 100) • Significance &# in familial breast cancer . . can . lie deep in . family . tree. San Ming . Wang. University of Nebraska Medical Center. Genetically defined breast cancer. Sporadic . B. reast . C. ancer . caused by . Research Update: Focus on Two Large Federally Funded Projects:. LEFFTDS and ARTFL. David Knopman MD. Neurology. Mayo Clinic. Rochester MN. MAPT. GRN. C9ORF72. FUS. Rarer genes. Sporadic. Tauopathy. TDP43opathy. Developed by . Ms. . Shawna . Morrison, Dr. Judith . Allanson. and Dr. June Carroll. Last updated . October 2016. Disclaimer. This presentation is for educational purposes only and should not be used as a substitute for clinical judgement. GEC-KO aims to aid the practicing clinician by providing informed opinions regarding genetic services that have been developed in a rigorous and evidence-based manner. Physicians must use their own clinical judgement in addition to published articles and the information presented herein. GEC-KO assumes no responsibility or liability resulting from the use of information contained herein. . Last updated: March 2021. GI cancers comprise a heterogenous array of tumor types. 1. . Pourhoseingholi MA, et al. . Gastroenterol. . Hepatol. Bed . Bench 2015;8(1):19; 2. . GI Cancer Alliance. GI Cancers. http://www.gicancersalliance.org/gi-cancers (. Bita. . Mirzaei. MD. Endocrinology Fellow. Research Institute for Endocrine sciences. Shahid. . Beheshti. University of Medical Sciences . Mordad. 94. . Silent . pheochrmocytoma. ?. Familial . pheochromocytoma. Who is Genetic Services?. Administrative Staff . Genetic Counsellors. Clinical Geneticists. Registries (Familial Cancer). Research Nurses . Laboratories. Clinical staff divided into three. different areas:. - 1 - AbstractA healthy 31-year-old woman presented with a 20-year history of asymptomatic skin-colored papules and nodules on the central area of the face. Her maternal grandmother, aunts, mother, a Patients in the Hereditary Cancer Network Database Background: Mutations in BRCA1 and BRCA2 genes increase an individual’s lifetime risk of breast cancer up to 80 percent, ovarian cancer up to 3 Professor, George Washington University Law School. B.A., Michigan State Univer-sity (English), M.S., University 310 Harvard Journal of Law & Technology [Vol. 23 For three years in the early 1980s, Assistant professor- Department of Pathology. Group . A & B 1. st. . year- . 18. th. . Moharruam. 1437. Osamah T. Khojah. 0555485892, asd@ksu.edu.sa. Objectives. Understand that incidence of cancer varies with age, race, geographic and genetic factor.. Fathaddin,MD. Assistant professor. Department of Pathology. Objectives. Understand that incidence of cancer varies with age, race, geographic and genetic factor.. Explain the categories of genetic predisposition to cancer..