PPT-Haemophilia in practice

Dr C E du Toit Groote Schuur Hospital An inherited Xlinked lifelong bleeding disorder affecting males almost exclusively Factor VIII deficiency Haemophilia A Factor IX deficiency Haemophilia B. of the . Efficacy of. Prophylactic Use . of . rFIXFc and . rFIX. . Products and . Simulation . of the . Effect . of . Compliance on Effectiveness. Alfonso . Iorio. , MD, PhD. 13 May 2014. A. lfonso Iorio,. Shaping the future of haemophilia togethe r A teacher’s guide to HaemophiliaHaemophilia is a rare condition. Largely because it is so rare, there are a lot of myths and misconceptions about hae Sex linkage . and multiple alleles. Starter – sickle cell anaemia. Genotype. Hb. A. Hb. A. Hb. A. Hb. S. Hb. S. Hb. S. Phenotype. Normal. Sickle cell trait. Sickle cell anemia. Type of heamogolbin. New Zealand Haemophilia Treatment Centres provide comprehensive and specialized care for people with haemophilia and bleeding disorders. North Island Auckland Auckland Haemophilia Centre Level 5 , Shaping the future of haemophilia togethe r Is this book for me?This book is intended for the parents of a child with mild or moderate haemophilia and for the children themselves when they are ready t Shaping the future of haemophilia togethe r Acquired HaemophiliaAdvice for people who have been diagnosed with acquired haemophilia Shaping the future of haemophilia togethe r IntroductionThis booklet Alfonso . Iorio. . MD, PhD. McMaster. University. Canada. BeneF. ix. ®. (. nonacog. . alfa. ) is . not currently approved . for once-weekly prophylaxis . treatment. Alfonso Iorio. Bayer, . Biogen. Bec. and Jessie. What is the cause of the disease?. It is caused by a defect in one of the genes that determines how the body makes blood clotting factor VIII or IX.. These genes are located on the X chromosomes. . notprovideresourcesfortreatingrare,chronic,andexpensiveconditions(suchashaemophilia)sincetheyfocustheirlimitedresourcesonpublichealthissuesthataffectlargerportionsofthepopulation,e.g.familyplanning,sa perspectives . and . the Kenyan Situation. .. Dr. Festus . Njuguna. Moi. University/MTRH. INTRODUCTION. Genetic X-linked disorder. Haemophilia. A and B. Affects 1 per 10,000 deliveries. 30% of cases due to new mutations. Amy Crowther. What is Haemophilia?. Haemophilia is a coagulation disorder.. The responsibility of blood clotting is down clotting factors in the blood. People with haemophilia have low levels of Factor VIII and Factor IX.. Irish Haemophilia Society . C. onference, . Dunboyne. , September 2016. Niamh Murphy & Dr Lelia Thornton. Timeline of . haemophilia. treatment and hepatitis C and HIV infection. Hepatitis C and HIV Infection. Professor Mike Laffan. What can go wrong with haemostasis?. Haemostatic Plug Formation: An Overview. Vessel constriction. Formation of an unstable platelet plug. . -platelet adhesion. -platelet aggregation. Alfonso Iorio, MD, PhD. Health Information Research Unit & Hemophilia Program. McMaster. University. Canada. Alfonso Iorio. Biogen. . Idec . (Bayer, Baxter, . NovoNordisk. , Pfizer - No conflicts).