Dr EW Müller Aetiology Infections with acute or chronic lymphadenitis Tumors Congenital Thyroglossal cyst Epidermoid cyst Branchial cyst or fistula Lymphangioma Haemangioma and arteriovenous malformations ID: 745609
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Neck masses in children
Block 12 – Head and Neck 2012
Dr EW MüllerSlide2
Aetiology
Infections with acute or chronic lymphadenitis
Tumors
Congenital
Thyroglossal cyst
Epidermoid cyst
Branchial cyst or fistula
Lymphangioma
Haemangioma and arterio-venous malformationsSlide3
Infection: Acute lymphadenitis
Most common cause: Bacterial infection of the oropharynx, face or scalp: Tonsillitis, Pharyngitis, impetigo of the scalp
Organisms: Staph aureus, Streptococcus
Clinic: Multiple tender lymph nodes in the submandibular or anterior cervical region. The lymph nodes are smooth, soft, not matted, mobile. Fever, systemic illness.
Initial treatment with antibiotics (Cloxacillin, Ampicillin) often results in resolution without suppuration.
Without (and with) treatment, the lymph node may become enlarged and fluctuant, leading to abscess formation.
An abscess needs surgical drainage.Slide4
Drainage pathways
Face, anterior scalp, forehead drain into facial, preauricular, submental LNs
Tonsills, posterior pharynx drain into jugulodigastric, deep cervical LNs
Posterior scalp, back of ear, external ear drain into posterior superficial cervical, posterior auricular, occipital LNsSlide5
Infection: Chronic lymphadenitis
Clinic: Chronically enlarged, non-tender lymph nodes.
Differential diagnosis: Tb, atypical mycobacterial infection, cat scratch disease; malignancy
A single, dominant lymph node (>2cm big) present longer than 6 – 8 wks, which has not responded to antibiotic therapy, should be excised, cultured, and submitted for histological examination.
HIV – often associated with Tb, lymphoma. Look for abnormally large lymphnodesSlide6
Neoplasms
Lymphoma: By far the most common childhood neoplasm presenting with enlarged lymph nodes in the neck.
Lymph nodes are usually rubbery, non tender and fixed. They may enlarge quickly.
Diagnosis: By biopsy of enlarged lymph node. Slide7Slide8
Congenital neck masses
Branchial Cysts and Sinuses
Thyroglossal duct cyst
Dermoid and epidermoid cyst
LymphangiomaSlide9
Branchial Cysts and Sinuses
These are remnants of the branchial apparatus which develops between the 4
th
and 8
th
week of pregnancy.
The apparatus consists of 4 branchial arches separated by branchial clefts. If the clefts fail to regress, a sinus or cyst will form.Slide10
Embryonic branchial apparatus
Inferior parathyroid and thymus
Superior parathyroid and parafollicular cells
Mandibula and Maxillary process of the upper jaw
HyoidSlide11
Branchial remnants
Present as fistulas or cysts anywhere on the anterior border of the sternocleidomastoideus muscle
Cyst presents with nontender enlarging swelling
Fistula presents with drainage of saliva from the ostium
Treatment: Early excision
Complication: Cysts and fistulas can become infected if not resected early in childhoodSlide12
Thyroglossal cyst - Embryology
The foramen caecum is the site of the development of the thyroid at the base of the prospective tongue. As the tongue develops, the thryroid diverticulum descends in the neck, maintaining its connection to the foramen caecum. A cyst can be located anywhere along the migratory tract if it fails to become obliterated.Slide13
Thyroglossal cyst - Clinic
Thyroglossal cysts are located in the midline at or just below the hyoid bone.
Due to communication with the mouth via the foramen caecum the cyst can become infected.
The cyst is smooth, soft and non-tender.
Owing to its attachment to the foramen caecum, the cyst does move upwards when the tongue protrudes.Slide14
Thyroglossal cystSlide15Slide16
Thyroglossal cyst - Treatment
Early surgical excision to avoid the complications of infection
Surgery entails complete excision of the cyst and its tract upward to the base of the tongue (Sistrunk Operation)Slide17
Epidermoid cysts
Represent ectodermal elements, which where trapped beneath the skin
Epidermoid cysts contain sebaceous material within the cyst cavity.
Most common location is at the lateral corner of the eyebrow. Presents with a characteristic swelling.
Midline epidermoid cysts develop due to entrapment of epithelium of branchial arch origin at the time of embryologic midline fusion. They might be confused with midline thyroglossal duct cysts.Slide18
Lymphangioma
Lymphangiomas are congenital malformations of lymph tissue that result from the failure of lymph spaces to connect to the rest of the lymphatic system.
Lymphangiomas present as a soft, smooth, nontender mass that is compressible and can be transilluminated.
Depending on the size and location, there might be respiratory compromise and difficulty in feeding.Slide19
Lymphangioma: Treatment
Goals: Improvement of cosmetic appearance, relieve of impaired breathing and eating.
Big lesions causing respiratory embarrassment might need urgent intubation at birth.
Surgery is difficult because of the infiltrative nature of these lesions.
Preferred treatment is infiltration with Bleomycin, alcohol or other scerosing agents.Slide20
Haemangiomas
Haemangiomas are benign tumors of the capillary vessels of the skin
They can occur anywhere, but are common in the face and neck
Typical growth, stationary and involutionary phase
Treatment : conservative (wait and see); excision or sclerosation