PPT-Metastatic HER2-Positive Breast Cancer: Treatment Selection

First Line and Beyond Moderator Joseph Gligorov MD PhD Head Cancer Coordination Center HUEP University Cancer Institute Sorbonne University Paris France Panelist Carlos H Barrios . Elaine R. Mardis, Ph.D.. Professor of Genetics. Co-director, The Genome Institute. NCI Workshop: NGS in Clinical Decision Making. Why is cancer WGS analysis “easy”?. The comparison of a patient’s tumor to their normal genome . A sub-focus on specific clinical scenarios. What to talk about?. Brain Metastatic Disease. CKD inhibition. HDAC inhibition. Androgen Receptor inhibition. mTOR. inhibition. Checkpoint Inhibition . Case Study. . Dr.Mina. . Tajvidi. Radiation . oncologist. . Fewer than 10 percent of women present with metastatic disease at the time of diagnosis. the majority of women who relapse after definitive therapy for early stage or locally advanced disease will do so with disseminated metastatic disease rather than an isolated local recurrence. ASCO-CAP Recommendations For HER2 Testing in Breast Cancer. Criteria For Reporting HER2 Test Results . as Positive. Criteria for Reporting HER2 Test Results . as Negative. Criteria for Reporting Equivocal Results . Mohammad . Jahanzeb. , MD, FACP. Professor of Clinical Medicine, Hematology-Oncology. Director, UM Sylvester Deerfield Campus. Associate Center Director for Community Outreach. Sylvester Comprehensive Cancer Center. Management of HER2 Over-Expressed Breast Cancer in the Adjuvant, Neoadjuvant, and Metastatic settings Christy A Russell, MD Keck School of Medicine University of Southern California Metastatic Breast Cancer Heather M. Gage, MD, Avanti . Rangnekar. , Robert E. Heidel, . PhD. , Timothy Panella, MD, John Bell, MD, and Amila Orucevic, MD, . PhD. The Graduate School of Medicine. The Department of Pathology. Introduction. Most of these lesions are benign. Breast cancer is 2. nd. most common cause of cancer deaths in women, following. carcinoma of the lung. . The clinical significance of the . benign. conditions:. 1- possible clinical confusion with malignancy. ENHERTUSignificantlyImproved Both ProgressionFree and Overall Survival in DESTINYBreast04 Trial in Patients with HER2 Low Metastatic Breast Cancer FirstHER2 low metastatic breast cancer ENHERTU of HOPC. Mrs GV is a 78 year old women who presented to Cabrini ED with acute dyspnoea is the setting of recent malignant pleural effusion in the setting of Metastatic Breast Ca.. Nov 2010: Self Detected left breast lump (AJCC Stage . Background of lower back pain for 3/12 . No past medical Hx.. Social Hx: . Married 2 small children, works in hospital admin. Regular Menstrual periods. Family Hx: . Aunt: Breast Ca 55. Aims. O/E:. Palpable LN under the right axilla. ishtiaq. . FCPS R3 general surgery unit one UKSO . prof . tariq. . ghaffor. . sb. . . Objectives. Surgical Anatomy. Investigations. Diagnosis. Elana Plotkin, CMP-HC. 1. , Marianne Gandee, MA. 2. , Lorna Lucas , MSM. 1. 1 Association of Community Cancer Centers, Provider Education, Rockville, MD, USA 2 Association of Community Cancer Centers, Development, Rockville, MD, USA. Dr. Sonalika’s Eye Clinic provide the best Conjunctivitis (Pink Eye) treatment in Pune, Hadapsar, Amanora, Magarpatta, Mundhwa, Kharadi Rd, Viman Nagar, Wagholi, and Wadgaon Sheri