PPT-Metastatic Breast Cancer

A subfocus on specific clinical scenarios What to talk about Brain Metastatic Disease CKD inhibition HDAC inhibition Androgen Receptor inhibition mTOR inhibition Checkpoint Inhibition Case Study. Elaine R. Mardis, Ph.D.. Professor of Genetics. Co-director, The Genome Institute. NCI Workshop: NGS in Clinical Decision Making. Why is cancer WGS analysis “easy”?. The comparison of a patient’s tumor to their normal genome . Jennifer M. Matro, MD. Rena Rowan Breast Center. Abramson Cancer Center. University of Pennsylvania. Overview. What is metastatic breast . c. ancer (MBC)?. Who is at risk?. Subtypes of Breast Cancer. What’s Positive about Triple Negative Breast Cancer ? Julie R. Gralow, M.D. Jill Professor Endowed Professor of Breast Cancer Director, Breast Medical Oncology Seattle Cancer Care Alliance University of Washington School of Medicine BRCA2 is a tumor suppressor gene responsible for DNA repair . BRCA2 was discovered in breast cancer tumors of patients without BRCA1 mutations. Mice knockouts discovered that BRCA2 is directly involved in double strand break repair. VeruInc Oncology Biopharmaceutical Company Focused on Prostate Cancer and Breast CancerVeru Corporate PresentationJefferies Virtual Healthcare ConferenceJune 1 June 4 2021Forward looking statements2Th Steven J. Katz MD MPH. Professor of Medicine and Health Management and Policy. University of Michigan . Allison Kurian MD M Sc.. Professor of Medicine and Medical Genetics . Stanford University . Guidelines 2019. World Congress on Breast Cancer . . Birmingham, UK. . August , 2015. Yvonne Paterson, Ph.D. ., University of Pennsylvania, USA. Nicola Mason, . B.Vet.Med. , . PhD, University of Pennsylvania . Breast Cancer : How important is it? . It is the most common cancer among women in lower-and-middle-income in Asian countries. . Its cost to society in terms of . - use of healthcare resources . Most of these lesions are benign. Breast cancer is 2. nd. most common cause of cancer deaths in women, following. carcinoma of the lung. . The clinical significance of the . benign. conditions:. 1- possible clinical confusion with malignancy. L. MEYSKENS, D. (32, 33), and hormonal (42, 46, (60, 78). 57, 66, cancer in is less Klinefelter'n syndrome with male authors measured et al. the formation ofestrone results rerrmin in males been repo ENHERTUSignificantlyImproved Both ProgressionFree and Overall Survival in DESTINYBreast04 Trial in Patients with HER2 Low Metastatic Breast Cancer FirstHER2 low metastatic breast cancer ENHERTU of Key recommendations. 1. National and local workforce planning is essential. Health Education England and all Cancer Alliances should urgently ensure there are enough healthcare professionals to deliver high-quality and timely diagnosis, treatment and care to local women.. Elana Plotkin, CMP-HC. 1. , Marianne Gandee, MA. 2. , Lorna Lucas , MSM. 1. 1 Association of Community Cancer Centers, Provider Education, Rockville, MD, USA 2 Association of Community Cancer Centers, Development, Rockville, MD, USA. Jo Anne Zujewski, M.D.. June 2019. Thimphu. , Bhutan. Define the breast cancer. Is the cancer operable?. Stage 1: systemic therapy after surgery (and radiation if breast conservation). Stage 2: systemic therapy before or after therapy.