PDF-An Introduction to MUTYH Associated Polyposis MAP

An Introduction to MUTYH Associated PolyposisMAPContentsWhat is MUTYH Associated Polyposis MAP What causes MUTYH Associated Polyposis MAP 3 How is MAP inherited 4 enetic Testing 5 ow is MAP m. Smad4 is a key part of TGF beta signaling pathway. Inhibits epithelial cell growth. SMAD4 is a tumor suppressor. . that was discovered in association with pancreatic cancer. De . Bosscher. . et al., . Serrated Polyposis Joanne Young Familial Cancer Laboratory QIMR Australia Serrated Polyposis • Group of conditions characterised by multiple serrated polyps (5 - 100) • Significance &# Polyposis. Syndromes in the Mediterranean Region. Thomas M Attard MD FAAP FACG. Associate Professor, Pediatrics, Gastroenterology, University of Malta, Malta. . Consultant Gastroenterologist Children’s Mercy Hospital, Kansas MO, USA.. Mary McCullum, RN, MSN, CON(C). Nurse Educator, Hereditary Cancer Program. BC Cancer Agency. September 22, 2017. Objectives. Identify hereditary polyposis syndromes. Review hereditary cancer/polyposis referral process. Familial Adenomatous Polyposis. Dr. Paymon Ashley Zomorodian. North West School of Radiology. Case courtesy of Dr. Rebecca Wiles, Consultant. Radiologist at Liverpool University Hospitals. Case Synopsis:. 358 Vol.7; Issue: 2; February 2017 International Journal of Health Sciences and Research www.ijhsr.org ISSN: 2249 - 9571 Case Report Familial Adenomatous Polyposis with Synchronous Invasive Maligna Marco Novelli FAP, MAP, NAP and PPAP Marco Novelli Overview • History of polyposis • Familial adenomatous polyposis • MYH - associated polyposis • NTLH1 - associated polyposis • Other polypo IMAJ • VOL • septe Background:atients with multiple (< 100) colorectal adenomatous polyps are at increased risk for colorectal cancer. Genetic evaluation of those patients who test negative for Posted on Friday, March 12, 2004 DURHAM, N.C. -- Two seemingly disparate hereditary syndromes actually stem, in some patients, from a uke University Medical Center genejuvenile polyposis -- characteri Familial adenomatous polyposis Key facts • Familial adenomatous polyposis (FAP) is an autosomal dominant condition, resulting in an extremely high risk of colorectal cancer, together with other Authored by Prof Michael C Herbst [D Litt et Phil (Health Studies); D N Ed; M Art et Scien; B A Cur; Dip Occupational Health] Approved by Ms Elize Joubert, C hief E xecutive O fficer [BA Social Wor adults: The focus on hereditary cancer syndromes Emmanouil Saloustros MD, DSc Hereditary cancer clinic University hospital of Heraklion – General hospital ‘ Venizelio ’ Heraklion, Crete, GREE Version 10 Contact details Regional Genetics Service Levels 4 - 6, Barclay House 37 Queen Square London, WC1N 3BH T +44 (0) 20 7762 6888 F +44 (0) 20 7813 8 578 Samples required  Tumour testing: Maha. . Arafah. Dr. Ahmed Al . Humaidi. Benign . Tumors. of Intestine. Learning Objectives. Know the classification of intestinal tumors (small intestine and colon). Know the definition of a polyp..