INTRODUCTION TO INDUSTRIAL PHARMACY 2023-2024 Practical It involves the application of various scientific principles and techniques to produce safe, effective and affordable drugs for use in the treatment, prevention, and diagnosis of
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INTRODUCTION TO INDUSTRIAL PHARMACY 2023-2024
Practical<br>
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It involves the application of various scientific principles and techniques to produce safe, effective and affordable drugs for use in the treatment, prevention, and diagnosis of diseases. Properties of Dosage Form<br>
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Requirements to Formulate Dosage Form Physicochemical properties of active ingredient and additives
Physical properties: Appearance, Texture, Color, Odor, Taste, Melting point, Boiling point, Density, Solubility
2. Chemical properties: Oxidation, Decomposition, Crystal structure, Toxicity, Thermodynamic properties<br>
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1. Research and development department
encompasses the early stages of the drug development process. Roles within this sector typically involve you working within a laboratory where you will identify molecules to be used in developing new medicines to treat a specific disease. Department of Drug Industry A- Small Scale department (pilot plant)
B- Responsible for formulation of a new dosage forms
C- Need Wikipedia pharmacist
2- Production department
Area for production of tablets, capsules, ampoules and solutions
Which deals with Large scale department, Need skilled workers<br>
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3. Quality control department To ensure that products meets the requirements specified by the official monographs and to ensure that there is no differences between batches for the same company within accepted evaluations.
4- Marketing department:
Responsible for marketing of drugs to pharmacies and hospitals. Marketing department activities refer to the various efforts and strategies that a company employs to promote its products or services to potential customers
5- Non-laboratory department:
Responsible for finding markets for dispense, management, accounting and personnel.<br>
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Drug Factories Requirements<br>
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Equipment used in laboratory 1. tablet Equipment 1. sieves : to get uniform particle size - Coulter counter Measure number of particles and size (< 1µm). - Sub-sieve sizer
Separate particles according to their size (0.2 to 50µm range).<br>
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2- Mixers<br>
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(4) Tablet machine<br>
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(7) Evaluation equipment 1. Flow meter: measure the flowability of the tablets powder mixture.
2. Flame photometer: measure the concentration or amount of ions such as K+ and Na+.
3. Hardness tester: measure the hardness of the tablet
A. Manual hardness tester such as Monsato hardness tester.
B. Electrical hardness tester such as Erweka hardness tester
4. Tablet friabilator: measures the tablet friability that means very friable tablet crack rapidly or very solid tablet will not crack easily.<br>
