PPT-Epigenetics : Nuclear transplantation &

Reprogramming of the genome Historical perspectives Big question nuclear cloning is possible genome of differentiated cells is identical to that of undifferentiated cells New concept Reprogramming somatic to embryonic epigenetic state. Kevin Ferriter. Mariah Minder. From Yesterday…. Do you think your brain cell and your blood cell have the same DNA sequence?. Genetics. Every cell contains all of your DNA. Not every cell expresses all of your DNA. :. DNA . methylation. II. DNA . methylation. in plants (Ch9). Differences between plants and animals. Auxotroph . vs. . heterotroph. Sessile . vs. . mobile. Motionless and rigid . vs. . migrating and flexible cells. Daniel Messinger. , Ph.D.. Messinger. Hmmm…. ‘Mothers . who were . pregnant during a 1944 famine in the . Netherlands. were . more likely to have children—and grandchildren—prone to heart disease, diabetes, and obesity. . Presentation by Peter Huessy of the Mitchell Institute/AFA to the SDC Symposium, June 20-21, 2016 Albuquerque, New Mexico. WHERE HAVE WE BEEN? . WHAT ARE WE TRYING TO DO? . WHERE ARE WE TRYING TO GO?. Joo. ’ Kim. Louisiana State University. What is . Epigenetics. ?. “the study of mitotically and/or . meiotically. heritable changes in gene function that can not be explained . by changes . in DNA sequences” – (Riggs et al. 1996). http://www.knowabouthealth.com/wp-content/uploads/2010/06/mcdonalds_.jpg. http://emilyscarenhealth.wordpress.com/2011/10/04/attention-a-must-read-for-smokers/. Can “. nuture. ” change “nature” ?. Introduction . Patients who undergo renal transplant require complex care. Diligent, multidisciplinary approach. Knowledge of patient’s history pre-, during and post-transplant. Surgeons, Nephrologist, consultants, PCP and allied health professional all work to direct transplantation efforts and . HISTORICAL DEVELOPMENT OF TRANSPLANTATION. . Experiments with organ transplantation started in. 19th century but were unsuccessful due to bad. surgical techniques and lack of knowledge on immune incompatibility. nuture. ; how our environment talks to us, sometimes forever.. Nessa. Carey, The Epigenetics Revolution (2012). The epigenetics revolution is underway.. Nessa. Carey, The Epigenetics Revolution (2012). Jessica Wen, M.D.. The Children’s Hospital of Philadelphia. Nov. 3, 2018. Objectives. P. rimary functions of the liver. I. ndications . for Liver . Transplant. P. rocess of liver transplant evaluation and listing. SLIDE SET. Introduction. Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant. Source: Annual Report on Liver Transplantation 2020/21, NHS Blood and Transplant. Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant. JABLONKA & LAMB: CHANGING CONCEPT OF EPIGENETICSment. We will then consider the practical importance of epigenetics in med-icine, agriculture, and ecology and, finally, look at the implications thatre . Is . transplantation a final end, or a new start?. 10302010078 . Liu . Wangyuan. Key Words. Allograft: . grafts transplanted between individuals of the same species. MHC:. major histocompatibility complex. Stephen Croft (ORNL). Ramkumar Venkataraman (ORNL). Louise G. Worrall (ORNL). Robert D. McElroy Jr. (ORNL). Andrea Favalli (LANL). Acknowledgement. This work was sponsored in part by the U.S. Department of Energy (DOE), National Nuclear Security Administration (NNSA), Office of Defense Nuclear Nonproliferation Research and Development (NA-22) and in part by ORNL and LANL..