PPT-Evolving Role of the CV Clinician in Managing CV Risk in Type 2 Diabetes: Rationale and

Nathan D Wong PhD FACC FAHA FNLA FASPC Professor and Director Heart Disease Prevention Program Division of Cardiology University of California Irvine Editorial Lead ACC Diabetes and Cardiometabolic Clinical Topic Collection. Chapter 4. Jean-Marie . Ekoé. , . Zubin. . Punthakee. , Thomas Ransom, . Ally . PH . Prebtani. , Ron Goldenberg. Canadian Diabetes Association 2013 Clinical Practice Guidelines. Screening Checklist. A lifetime risk challenge. Priorities in the management . of . type 2 diabetes:. Past, present and future. Sir George Alberti, MD. Diabetes UK Chairman. Newcastle. , United Kingdom. Cardio. Diabetes . Tyrell Hardtke. Diabetes in the Family: A Case Study. CDC’s 2005 Science Ambassador Program. Today’s Question: . . You learn that type 2 diabetes “runs in the family.” . How can you avoid developing type 2 diabetes?. A lifetime risk challenge. Priorities in the management . of . type 2 diabetes:. Past, present and future. Sir George Alberti, MD. Diabetes UK Chairman. Newcastle. , United Kingdom. Cardio. Diabetes . Years from . diagnosis. 0. 5. -10. -5. 10. 15. Pre-diabetes. Onset. Diagnosis. Insulin secretion. Insulin “efficiency”. Ramlo-Halsted BA, Edelman SV. . Prim Care. . 1999;26:771-789 Nathan DM. . N Engl J Med. . Help patients with type 2 diabetes achieve their glycemic goals. 1. In the US, diabetes is the primary diagnosis for . 37 million visits. to a physician’s office, emergency department or outpatient hospital-based clinic . Preventing type 2 diabetes Wisconsin Women’s Health Foundation Mission : Innovate, impact, and improve women’s health Provides free health education and services in Wisconsin Preventive health screenings for women who are under-insured or uninsured Age (years). Genetic . Predisposition. Beta cell mass. (?Precipitating Event). Overt. immunologic. abnormalities. Normal insulin. release. Progressive. loss insulin. release. Glucose. normal. Overt. diabetes. Jessica Dunne, Ph.D.. Director, Research. JDRF. Hello…. Jessica Dunne, Ph.D.. Joined JDRF in . September 2008, Lead for Prevention program since its inception in July 2012. 14 . yrs. in immunology/inflammation/vaccine research including in the pharma and biotech sectors. Figure 1 T1D Incidence Rates Worldwide 0510152025303540FINSARSWENORUS-WIUS-PAITAISRJAPCHIare being diagnosed with the T1D around the world each year Although the peak age at onset is at puberty T1D Ching Yee Ngan. Practice Support Pharmacist. City and Hackney CCG. ching-yee.ngan@nhs.net. Learning objectives. Type 2 diabetes recap and complications. Management of type 2 diabetes. Non-pharmacological, including diet. Type 2 Diabetes. High blood glucose. Insulin secretion from pancreas. ↑ Glucose absorption by muscle. Low blood glucose. Eat. Analyzed genome sequence of Steve Quake. Rare protein altering SNPs . But usually do not know what the gene does, so difficult to know if the mutation is causing a trait..  BPJ Key practice points Emphasise the importance of lifestyle change as the foundation of all treatments for type 2 diabetes and ensure all patients have access to self-management education Diana Isaacs, PharmD, BCPS, BCACP, CDCES, BC-ADM, FADCES, FCCP. Endocrine Clinical Pharmacy Specialist. CGM and Remote Monitoring Program Coordinator. Cleveland Clinic Endocrinology and Metabolist Institute.