Elisabeth Bing Mother of Lamaze Dies at 100 Howard Jones dies at 104 Responsible with wife Georgeanna Seegar Jones for the first IVF baby in US Pioneered sexchange surgeries ID: 1034820
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1. ObG WatchNarayanan RSeptember 2015
2. Elisabeth Bing, ‘Mother of Lamaze’ Dies at 100
3. Howard Jones dies at 104Responsible with wife Georgeanna Seegar Jones for the first IVF baby in USPioneered sex-change surgeries
4. The accompanying editorial commentary put the studies into perspective and supplied authoritative guidance
5. Role of Progesterone in RPL Progesterone indispensable for progress of pregnancyDeficiency of P in luteal phase (LPD) causes miscarriage (probably in >20% of all MC)No current method to prove P deficiencyHence P treatment is empirical at bestP has no place in natural unstimulated pregnancy unlike in ART assisted pregnancies (2015 Committee Opinion by the American Society of Reproductive Medicine)May be tried in RPL (>3) empirically after FH detected until 8-10 weeks of gestation. Evidence poor. (Clin N Am, Mar 2015 Vol 42 No 1)Oral or Vaginal? – Issue not resolvedResults of PROMISE Trial awaited
6. Non invasive Prenatal testing (NIPT)Done around 10th week-uses cell-free DNAFocuses primarily on the viable trisomies 13, 18, and 21. Detects Down syndrome in 99.2% The test has low false positive ratesContributed to >50% reduction in invasive procedures such as amniocentesisCan throw up surprise results
7. NIPT can save livesNIPT interrogates not only fetal DNA in maternal plasma but also cancer DNACan identify presymptomatic tumorsAmong 4000 samples 3 had abnormal genome profilesWhole body MRI revealed cancer in all 3 women Vermeesch et al, June 5, JAMA Oncology 2015
8. One had high-grade serous cancer in both ovaries with diffuse peritoneal spread, multiple metastases, and lymph node involvement. She underwent successful treatment after delivery.The second patient had follicular lymphoma and did not undergo treatment because of the slow-growing nature of this cancer. The third patient had Hodgkin lymphoma. She received treatment during pregnancy and gave birth to a healthy girl.
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10. Benefits in Non human mothers Increases interaction between mother and infantPotentiates pregnancy-mediated analgesia in the motherStimulates maternal brain opioid circuits that facilitate the onset of caretaking behaviorSuppresses postpartum pseudopregnancy (Ecology of Food and Nutrition Vol 51, Issue 3, 2012)
11. No proof but Speculation persists… Is Placentophagia the answer to… Postpartum depression Failure to bond Hostility toward infants
12. At last, a Pink viagra?
13. Sexual dysfunction affects 10% of women in USThey are chiefly, Hypoactive sexual desire disorder (HSDD) or Female sexual arousal disorder (FSAD) or both conditions Bremelanotide (BMT or flibanserin), a novel heptapeptide melanocortin-receptor-4 agonist yields promiseApproved by USDA in August 2015Clayton.A, American Society of Clinical Psychopharmacology (ASCP) 2015 Abstract presented June 23, 2015.
14. 100 mg tab at bed timeIncreases Satisfying Sexual Events (SSEs)Improvement after 4 wks of daily treatmentSE: drowsiness/hypotension/syncopeAlcohol intake causes hypotensionMarketed as ADDYI
15. HE-MEN of SHE-CUPBreak throughs in small initiativesChartered accountant turned entrepreneurs manufactureThe first Indian brand of Reusable Menstrual cupCost Rs 675.00India Today August 24, 2015
16. Made of high grade SiliconFlexibleCan be kept for 12 hoursRewashableReusable many years
17. Summer BabiesChildren born in June, July and August face the so-called "birth-date effect“They are statistically likely to perform less well than their older classmates These sunshine-month youngsters never catch up with their older winterish peers In a major overview, Cambridge concluded that summer babies were "strongly disadvantaged“At the end of primary school the difference on average stands at 12%! ObG Watch-July 2013
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20. 3D Printing
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