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Model N included in model Model N included in model

Model N included in model - PowerPoint Presentation

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Uploaded On 2023-10-28

Model N included in model - PPT Presentation

Variable RR 95 CI Missing SBP and base excess imputed 543 ENDO vs OPEN 058 046073 RT vs OPEN 300 184490           Transferred 9 OPEN patients with initial endovascular procedures to the ENDO group missing data imputed ID: 1026207

data figure simulated fig figure data fig simulated residuals supplemental deviance suppl excess base sbp missing imputed patients model

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1. ModelN included in modelVariableRR95% CIMissing SBP and base excess imputed543ENDO vs OPEN0.580.46-0.73RT vs OPEN3.001.84-4.90     Transferred 9 OPEN patients with initial endovascular procedures to the ENDO group (missing data imputed)543ENDO vs OPEN0.610.46-0.82RT vs OPEN2.991.76-5.10     Excluded patients with missing SBP or base excess data478ENDO vs OPEN0.570.45-0.72RT vs OPEN3.141.98-4.98Supplemental Table 1. Sensitivity analysis comparing mixed effects Poisson regression with robust error variance using imputed versus non-missing SBP and base excess. We controlled for age, ISS, mechanism, severe head injury (AIS head ≥3), shock (base excess <-4 mEq/L), and hypotension (SBP <90 mmHg) as fixed effects and site as a random effect. Incidence-rate ratios and 95% confidence intervals describe ENDO versus OPEN and RT versus OPEN on outcome of in-hospital mortality.

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12. Supplemental Figure 1. Deviance residuals versus predicted for the overall model with imputed missing SBP and base excess data (n=543).Supplemental Figure 2. Actual (black) versus simulated deviance residuals (grey, n=20) using simulated data generated by the model in Figure 1.Supplemental Figure 3. Deviance residuals versus predicted for patients without BTAI with imputed missing SBP and base excess data (n=488).Supplemental Figure 4. Actual (black) versus simulated deviance residuals (grey, n=20) using simulated data generated by the model in Figure 3.Supplemental Figure 5. Deviance residuals versus predicted for patients with chest NCTH with imputed missing SBP and base excess data (n=137).Supplemental Figure 6. Actual (black) versus simulated deviance residuals (grey, n=20) using simulated data generated by the model in Figure 5.Supplemental Figure 7. Deviance residuals versus predicted for patients with abdomen NCTH with imputed missing SBP and base excess data (n=225).Supplemental Figure 8. Actual (black) versus simulated deviance residuals (grey, n=20) using simulated data generated by the model in Figure 7.Supplemental Figure 9. Deviance residuals versus predicted for patients with pelvis NCTH with imputed missing SBP and base excess data (n=167).Supplemental Figure 10. Actual (black) versus simulated deviance residuals (grey, n=20) using simulated data generated by the model in Figure 9.