PPT-The Trust-TSC Phase 3 Clinical Trial for Seizures in TSC

Mary Kay Koenig MD Associate Vice Chair for Clinical Research CoDirector for the Tuberous Sclerosis Center of Excellence Department of Pediatrics Division of Child amp Adolescent Neurology University of Texas McGovern Medical School. Ryan . Em. C. . Dalman. MD MBA - 070070. “Co-co-co-com . Bulsyon. !”. “. ehem. …”. Outline. Objectives. Case Presentation. Case . Discussion. Objectives. Present a case of Simple Febrile Seizures. STS. 4/13/2015. Cerebrovascular Accident & Stroke. CVA: an interruption of blood flow to the brain. Stroke: loss of brain function due to a CVA. No. 1 risk factor: . hypertension. Other potential causes:. Learning objectives . Gain organised knowledge in the subject area of seizures and epilepsy. Be able to correctly interpret diagnostic information in people with seizures. Know and apply the relevant evidence and/or guidelines to different clinical presentations of seizures and epilepsy. PRESENTED BY. GERRY BROPHY. Training in Care Solutions. The brain is made up of billions of neurons, or nerve cells. These are the electrically charged units that, as they communicate with each other, organize electrical energy to make the brain work.. Supervised by: . Dr.amani. Done by :. Eman. Al-. otibi. Darin Al –. radadi. Dina Al-. amam. Ebtehal. Al-. yami. An 18 m. old baby is admitted to the hospital B/C he is suffering from fever and convulsion.. Chapter 22. Dr. Gary Mumaugh and Dr. Bruce . Simet. University of Northwestern St. Paul. Seizures. Sudden, transient alteration of brain function caused by an abrupt . explosive, disorderly. discharge of cerebral . A . condition of disturbed brain activity that causes changes in a person’s attention or behavior.. Epilepsy is a disorder in which a person has repeated seizures over a period of time. Seizures are a disorder of brain function due to a medical condition, injury to the brain or cause may be unknown. Seldom associated with brain damage.. Delin . Wang. Samir. Patel. Introduction. A seizure is a paroxysmal event due to abnormal, excessive, hypersynchronous discharges from an aggregate of CNS neurons.. Depending on the distribution of discharges, various manifestations can occur. DR.ADRIANA MOCANU. SEIZURES and . EPILEPSIES . Definition.  . . Seizure. - sudden . episode, stereotyped. , with changes in motor activity , behavior, . sezitivo. -sensory activity, emotional activity and often of . Dr. Gary Mumaugh and Dr. Bruce . Simet. University of Northwestern St. Paul. Seizures. Sudden, transient alteration of brain function caused by an abrupt . explosive, disorderly. discharge of cerebral . Director, Pediatric . Neuro. -Oncology. Hackensack University Medical Center. Tuberous Sclerosis Complex. and Seizures. “Knowledge is Power”. What is TCS?. Neurocutaneous. disorder. Neurologic structures and skin are derived from the same tissue in the embryo. yr. of age and are often, owing to their brevity, overlooked by parents for many months even though they can occur up to hundreds of times per day. The characteristic of the attack is a brief . arrest. immature brain has many differences from the mature brain that render it more excitable and more likely to develop seizures. . Generalized . clonic. seizures that are bilateral, symmetric, and synchronous are uncommon in the neonatal period presumably due to decreased connectivity associated with incomplete myelination at this age. . A Feasibility Study. SciSIP. PI Conference, September 2012. Ernst R. Berndt. Iain M. Cockburn. MIT, Boston University, and . National Bureau of Economic Research. What?. Analysis of trends in costs of doing clinical trials.