PPT-Immune Cell Ontology for Networks (ICON)

Immunology Ontologies and Their Applications in Processing Clinical Data June 1113 Buffalo NY Confessions I am an ontological newbie Idea for a new ontology of immune networks Immunologists Ive talked to like the idea. Immune Modulation, and Immunosuppression in MS: . A Review . Introduction. Architecture of the Immune System: Focus on Innate Immunity. Innate Immune System Features. Architecture of the Immune System: Focus on Adaptive Immunity. Super Awesome Powers of Cell Signaling!. Reminder - Do the Questions!. Do the questions, or Mrs. Davis will be so super sad. Plus, this stuff is AWESOME.. Immunologists. 10-11 years of schooling/training. Immune . Epitope Database and Analysis Project. La Jolla Institute for Allergy & Immunology. Division of Vaccine Discovery. La Jolla, California. 1. What is an epitope?. Antibodies and T cells bind to epitopes to trigger an immune response. Barry Smith, Alexander Diehl, Anna-Maria . Masci. Presented at . Leveraging Standards and Ontologies to Improving HIPC Data Submission and Analysis, National . Institiute. of Allergy and Infectious Diseases (NIAID), Rockville, MD, November 19 . Chapter 43. Innate Immunity. nonspecific defense that is active immediately upon infection. found in all animals & plants. includes:. outer covering. skin or shell. chemical secretions. @ openings to interior of body. Key attributes of immune system. 4 attributes that characterize the immune system as a whole. specificity. antigen-antibody specificity. diversity. react to millions of antigens. memory. rapid 2° response. The Immune System CAMPBELL and REECE Chapter 43 Innate Immunity nonspecific defense that is active immediately upon infection found in all animals & plants includes: outer covering skin or shell chemical secretions Key attributes of immune system. 4 attributes that characterize the immune system as a whole. specificity. antigen-antibody specificity. diversity. react to millions of antigens. memory. rapid 2° response. 8/1/2017 1 Conflicts and Grants - NIH (R01 EB009040) - NCI SBIR grant with Celldex Therapeutics, Inc. - Project Energy with Johnson & Johnson Chandan Guha, MBBS, PhD Professor and Vice Chair, Purpose of the Immune System . Protect from internal attacks from . abnormal body cells . (cancerous cells). Protect from . external pathogens. Can enter the body through any systems that have openings on the exterior of the body. Immunology. Study of the components and function of the immune system. Immune System . Molecules, cells, tissues and organs which provide non-specific and specific protection against. Microorganisms. Chapter 21. 2 Defense Systems. Innate Immunity. nonspecific defense that is active immediately upon infection. found in all animals & plants. includes:. outer covering. skin or shell. chemical secretions. IN CANCERS. HUỲNH QUYẾT THẮNG. VIETNAM CANCER SOCIETY. INHIBITORY IMMUNE CHECKPOINTS IN CANCERS. Immune checkpoint . Negative regulators of immune system. Maintaining self-. tolerence. Preventing auto-immunity. Four Major Categories of Immune Mechanisms. Humoral. or antibody-mediated immunity . (B lymphocytes). Cell-mediated immunity . (T lymphocytes). Complement system. Phagocytosis. . (. neutrophils. and macrophages) .