National Library of Medicine kilbourjmailnlmnihgov Topics Where does RxNorm data come from Organizing the data A current issue we are addressing Where does RxNorm data come from Source names same or different ID: 928092
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Slide1
RxNorm Overview
John Kilbourne MD
National Library of Medicine
kilbourj@mail.nlm.nih.gov
Slide2Topics
Where does RxNorm data come from?
Organizing the data
A current issue we are addressing
Slide3Where does RxNorm data come from?
Slide4‘Source’ names: same or different?
Slide5Source names vs. normalized name
Ranitidine 15 MG/ML Oral Solution
(normalized name
)
SY: ranitidine 15 MG (ranitidine hydrochloride
16.8 MG
) per ML
Oral
SolutionSY: ranitidine 75 MG per 5 ML Syrup
“Ranitidine Hydrochloride
15 MG
ORAL SYRUP”
“Ranitidine Hydrochloride
16.8 MG
ORAL SYRUP”
“Ranitidine Hydrochloride
75 MG
ORAL SOLUTION”
Slide6RxNorm and its sources
Free dataset published monthly (with weekly FDA adds) by NLM
Also a browser and API access to the data
Data
sources
aggregated and organized
FDA: Structured Product Label – SPL (DailyMed)
First Databank
MultumMicroMedexGold Standard
Medi
-Span
VA: NDF-RT and VANDF
SNOMED CT
Slide7Path of data for RxNorm
Slide8NLM-authored data
RxNorm content determined by the source data
Devices, drug classes, radiopharmaceuticals out of scope
Standalone non-commercial names and codes for e-prescribing and other uses
Slide9Endorsement and use of RxNorm
Center for Medicare and Medicaid Services (CMS)
Formulary Reference File
Clinical Quality Measures (CQMs), Meaningful Use Value Sets
Office of the National Coordinator (ONC)
Standard for medications and medication allergies
Required for Electronic Health Record (EHR) certification
National Council for Prescription Drug Programs (NCPDP)
SCRIPT e-prescribing standard
Formulary and Benefit standard
Veterans Affairs – Department of Defense (VA-
DoD
)
Slide10Organizing the
data
Slide11RxNorm building blocks:
term types (TTYs)
SCD: Center of the universe for RxNorm
Ingredient + strength + dose form
Azithromycin 250 MG Oral Tablet
SBD: SCD + Brand name (BN)
Azithromycin
250 MG Oral Tablet [Zithromax
]
Slide12Packs
GPCK: Collection of SCDs
{
6 (Azithromycin 250 MG Oral Tablet) }
Pack
{30 (Aspirin 325 MG Oral Tablet) / 30 (Pravastatin Sodium 20 MG Oral Tablet [
Pravachol
]) }
Pack
BPCK: GPCK with a suffix
{
6
(Azithromycin 250 MG Oral Tablet
[
Zithromax]) } Pack
[
Z-PAKS
]
{30 (Aspirin 325 MG Oral Tablet) / 30 (Pravastatin Sodium 20 MG Oral Tablet [
Pravachol
]) } Pack [
Pravigard
325/20]
Slide13SCD
Diazepam
5 MG Oral
Tablet
SCDC Diazepam 5 MG
SCDF Diazepam Oral Tablet
SCDG Diazepam
Pills
SBD
Diazepam
5 MG Oral Tablet
[Valium]
SBDC
Diazepam
5 MG [Valium
]
SBDF
Diazepam
Oral Tablet [Valium]
SBDG Valium Pills
BN ValiumIN Diazepam
Multiple levels of description
Slide14Counts of TTYs
SCD
20,094
SBD 11,068
GPCK 413
BPCK 337
IN 9237
MIN 3848
PIN 2184
Slide15“One-to-many” issues
Adenosine
3 MG/ML Injectable
Solution
Adenosine 3 MG/ML Prefilled Syringe
1
ML Adenosine 3 MG/ML Prefilled Syringe
2
ML Adenosine 3 MG/ML Prefilled Syringe
4 ML Adenosine 3 MG/ML Prefilled Syringe
Slide16Wrap-up
RxNorm is derived from other drug data
Drug classes, devices, radiopharmaceuticals out of scope
Endorsed and used by CMS, ONC, NCPDP, VA,
DoD
RxNorm organized by ‘TTY’; SCD is the center of the universe; SCD, SBD, GPCK, BPCK can be administered
Slide17Thank you
John
Kilbourne
MD
kilbourj@mail.nlm.nih.gov