PPT-Genetic testing in ovarian cancer

Dr Katie Snape Joint Lead Consultant for Cancer Genetics South West Thames Regional Genetics Service St Georges University Hospitals NHS Foundation Trust Approval ID GB17285 Date of Preparation June 2019. Ovarian Cancer. Epithelial Tumor, . postmenopausal women. Germ cell,. younger women. Sex cord-stromal origin,. any age. Approximately 90% of ovarian cancer is epithelial . significant . therapeutic challenges . Lisa McCluskey, MD. Gynecologic Oncologist. June 16, 2015. Compass Oncology . in partnership with . Ovarian . Cancer Alliance of Oregon & SW . Washington. What. is Ovarian Cancer. ?. The most common type of Ovarian Cancer that starts from . Diagnostic work-up. Treatment. The most commonly occurring gynecologic cancer is:. Cervical. Endometrial. Ovarian. Vulvar. The gynecologic cancer with the highest death rate is:. Cervical. Endometrial. Improvement in 5 Year Survival:. Race. 1975. 1989. 2014. All. 36%. 38%. 47%. White. 35%. 38%. 48%. African American. 42%. 34%. 39%. Noone. AM, . Howlader. N, . Krapcho. M, et al. (eds). SEER Cancer Statistics Review, 1975-2015, National Cancer Institute, Bethesda, MD, www.seer.cancer.gov/csr/1975_2015/, based on November 2017 SEER data submission, posted to the SEER website April 2018.. Siew. . wei. . wong. Oncology registrar. Epidemiology. 225000 new incidence annually worldwide. Incidence stable since 1970s. 1600 new cases in Australia in 2010. Median age at diagnosis 63. Fourth commonest cause of cancer death in women in developed countries. th. most incident and lethal cancer. New cases: 225,000 annually. Deaths: 140,000 annually. *Almost 75% of cases present with advanced stage .. *Risk of relapse of advanced stage disease is as high as 70%. Page 1of 26UnitedHealthcare Commercial Medical PolicyEffective 01/01/2021Proprietary Information of UnitedHealthcare Copyright 2021United HealthCare Services IncUnitedHealthcareCommercial MedicalPolic Laura . K. Fisher. , MS, CGC. Director . of Genetic . Counseling. October . 8, 2019. Outline. Genetic counseling. What happens at a genetic counseling appointment? . Who should see a genetic counselor?. Christopher Morse, MD. Fellow, Gynecologic oncology. UW MEDICINE. CONFIDENTIAL – DO NOT DISTRIBUTE. Overview. Introduction to ovarian cancer. Diagnosis and treatment. Surgery and chemotherapy. Surveillance. SH-Sheikh . hasani. GYN.Oncologist. Imamkhomeini. Hospital. Prevalence of Ovarian Cancer. the most lethal . gynaecological. tumor . . prevalence. : . 3.7. %. of all female cancers and for 4.2% of . (. Genomic Test Directory criteria R208): . Ask. patient to complete family history screening questionnaire. Germline/somatic genetic test pathway:. Clinical team discuss testing with the patient. Complete test request forms and record of discussion form. How common are BRCA1 and BRCA2 mutations in the general population? Inherited mutations in BRCA1 and BRCA2 are relatively uncommon in the general population. The carrier frequency is estimated to rang Genetics of ovarian cancer. 49F. Underwent risk-reduction surgery. Total hysterectomy and bilateral . salpingo. -oophorectomy. Significant family history . Sister passed away in her 40s due to breast cancer. Singh. MD (AIIMS), FICOG. Dept. of Obstetrics & Gynecology. King George Medical University. Lucknow. INTRODUCTION. Fourth most common cause of death in women. 30% of genital malignancies in the developed countries .