PDF-Genetic Testing for Hereditary Cancer

Page 1of 26UnitedHealthcare Commercial Medical PolicyEffective 01012021Proprietary Information of UnitedHealthcare Copyright 2021United HealthCare Services IncUnitedHealthcareCommercial MedicalPolic. Kalyani Maganti, M.D. ASCO. Chromosomes, DNA, and Genes. Cell. Nucleus. Chromosomes. Gene. Protein. ASCO. Disease-Associated Mutations. A “mutation” is a change in the normal . coding sequence of a gene. Raymond Kim. MD/PhD, FRCPC, FCCMG, FACMG. Medical Geneticist. Princess Margaret Cancer Centre. Outline. Genetic terminology and concepts. Hereditary cancers. When to consider. Genetics assessment. Surveillance. Kayla York, MS, LCGC. Licensed Genetic Counselor. Avera Cancer Institute. Outline . Genetic Counseling. Cancer Genetics. Breast/Ovarian Cancer. Colon/Endometrial Cancer . Summary. Genetic Counseling. Kristin . DePrince. Mattie, M.S.. Licensed / Certified Genetic Counselor. William G. Rohrer Cancer Genetics Program. Objectives. Describe . current approaches to genetic testing for hereditary cancer syndromes. Robert A. Somer, MD. Head, Medical Oncology and Hematology. Director, Office of Clinical Research. MD Anderson Cancer Center- Cooper. What is Cancer?. Official Definition: A malignant proliferation of cells that is a result of a . {Template Slide Set}. 1. Overview. What are Hereditary Breast and Ovarian Cancer syndrome (HBOC) and Lynch . s. yndrome (LS)?. How common are LS and HBOC? . How do LS and HBOC affect individuals and families?. Prostate cancer is the most common cancer in males Most men develop prostate cancer by chance or as a result of risk factors that occur over the course ofa lifetime However approximately 10percentof m UterineCancerMost people develop uterine cancer by chance or as a result of risk factors that occur over the course of a lifetime However up to 10percentof people who are diagnosed with uterine cancer gynaecological. cancers. Prof.. Nicoletta . Colombo. . Universita. ’. Milano Bicocca. Istituto Europeo Oncologia, Milano. Disclosures. I have acted as a consultant for AstraZeneca, . Clovis, . Review of Cancer Genetics Normally, cells grow, divide and make more cells in a controlled way as the body needs them to stay healthy. Cancer happens when a cell grows out of control in an abnormal w Prostate cancer is the most common cancer in males . M ost men develop prostate cancer by chance or as a result of risk factors that occur over the course of a lifetime. However, approximately 10 pe Uterine Cancer Most people develop uterine cancer by chance or as a result of risk factors that occur over the course of a lifetime. However, up to 10 % ( percent ) of people who are diagnosed with CancerGenetics@utsouthwestern.edu | 214 - 645 - 2563 Somatic and Germline Genetic Testing Somatic Testing Most cancer is the result of acquired, or somatic , mutations that occur in a cell. Cancers Cori Chandler, MPA. Sr. Manager, State & Local Campaigns – Access to Care. Genetic Testing. 2. Genetic Testing. What is it?. The testing of a person’s germline genes. This testing is typically performed using biospecimens such as blood or cells.