PPT-Hereditary cancer, the next generation

Raymond Kim MDPhD FRCPC FCCMG FACMG Medical Geneticist Princess Margaret Cancer Centre Outline Genetic terminology and concepts Hereditary cancers When to consider Genetics assessment Surveillance. Kalyani Maganti, M.D. ASCO. Chromosomes, DNA, and Genes. Cell. Nucleus. Chromosomes. Gene. Protein. ASCO. Disease-Associated Mutations. A “mutation” is a change in the normal . coding sequence of a gene. Kristin . DePrince. Mattie, M.S.. Licensed / Certified Genetic Counselor. William G. Rohrer Cancer Genetics Program. Objectives. Describe . current approaches to genetic testing for hereditary cancer syndromes. Robert A. Somer, MD. Head, Medical Oncology and Hematology. Director, Office of Clinical Research. MD Anderson Cancer Center- Cooper. What is Cancer?. Official Definition: A malignant proliferation of cells that is a result of a . Alix . d’angelo,. . mgc. , . cgc. February 13, 2017. SYNDROME OVERVIEW. HEREDITARY BREAST CANCER. SYNDROMES WITH BREAST CANCER. Hereditary Breast and Ovarian Cancer syndrome (. BRCA1, BRCA2. ). Li-. Polyposis. Syndromes in the Mediterranean Region. Thomas M Attard MD FAAP FACG. Associate Professor, Pediatrics, Gastroenterology, University of Malta, Malta. . Consultant Gastroenterologist Children’s Mercy Hospital, Kansas MO, USA.. Prostate cancer is the most common cancer in males Most men develop prostate cancer by chance or as a result of risk factors that occur over the course ofa lifetime However approximately 10percentof m UterineCancerMost people develop uterine cancer by chance or as a result of risk factors that occur over the course of a lifetime However up to 10percentof people who are diagnosed with uterine cancer Page 1of 26UnitedHealthcare Commercial Medical PolicyEffective 01/01/2021Proprietary Information of UnitedHealthcare Copyright 2021United HealthCare Services IncUnitedHealthcareCommercial MedicalPolic Mary McCullum, RN, MSN, CON(C). Nurse Educator, Hereditary Cancer Program. BC Cancer Agency. September 22, 2017. Objectives. Identify hereditary polyposis syndromes. Review hereditary cancer/polyposis referral process. Relatives should be on the same side of the family (first-degree relatives) ie. Parents, sibs, children (second-degree relatives) ie. Grandparents, aunts, uncles, grandchildren er, ovarian cancer Review of Cancer Genetics Normally, cells grow, divide and make more cells in a controlled way as the body needs them to stay healthy. Cancer happens when a cell grows out of control in an abnormal w Prostate cancer is the most common cancer in males . M ost men develop prostate cancer by chance or as a result of risk factors that occur over the course of a lifetime. However, approximately 10 pe Uterine Cancer Most people develop uterine cancer by chance or as a result of risk factors that occur over the course of a lifetime. However, up to 10 % ( percent ) of people who are diagnosed with GRACE C. FIRMALINO, MD, FPCS. July 13, 2020. ONCOLOGY. A branch of medicine concerned with the prevention, diagnosis, treatment and study of cancer . Primary (or definitive) surgical therapy – en bloc resection of tumor with adequate margins of normal tissues and regional lymph nodes with local and regional control as primary goal.