PPT-Breast Cancer Risk: Genes

and the Environment Note You will need to provide water and paper towels for participants Breast Cancer Risk Genes and the Environment Please complete the Participant Card 3. Kristin . DePrince. Mattie, M.S.. Licensed / Certified Genetic Counselor. William G. Rohrer Cancer Genetics Program. Objectives. Describe . current approaches to genetic testing for hereditary cancer syndromes. Susan M. Domchek, MD. Basser Professor of Oncology. University of Pennsylvania . Sex. Age. Family . history. Depends on specific of family history. Depends on whether there is a k. nown . genetic . susceptibility. Generosa. . Grana. , MD. Professor, Cooper Medical School of Rowan University. Director, MD Anderson Cancer Center at Cooper. Overview. Factors that affect breast cancer risk. Tools to assess risk. Role of genetics in this process. October 25,2017. Disclosures. None. Outline. Epidemiology. Risk Factors. Screening. Diagnosis. Treatment. Genetic testing. Research. Epidemiology. 2017 :estimated 252.710 new cases of invasive breast cancer in women. Rachna Raman MD MS. Hematology and Medical Oncology. Bon Secours Cancer Institute at St. Mary’s Hospital. Objectives. Risk factors . Screening guidelines and controversies. Screening and management of patients at high risk for breast cancer. BRCA1 and BRCA2. Jennifer . Hardee. Normal function of the genes. BRCA1 & BRCA2 are in the same DNA repair pathway. Despite names, do not share any protein structure. Both are . tumor suppressors . BRCA1 and BRCA2. Jennifer . Hardee. Normal function of the genes. BRCA1 & BRCA2 are in the same DNA repair pathway. Despite names, do not share any protein structure. Both are . tumor suppressors . BRCA2 is a tumor suppressor gene responsible for DNA repair . BRCA2 was discovered in breast cancer tumors of patients without BRCA1 mutations. Mice knockouts discovered that BRCA2 is directly involved in double strand break repair. Steven J. Katz MD MPH. Professor of Medicine and Health Management and Policy. University of Michigan . Allison Kurian MD M Sc.. Professor of Medicine and Medical Genetics . Stanford University . Guidelines 2019. Audience. : . GenEd. Biology . students. Linda Grisham, Massachusetts Bay Community College. Mark Maloney, Spelman College. Kim . Gernert. , Emory University . Inspired by the recent Angelina Jolie health . Interview with . Lauren . Segal. 15. th. March 2018. Top 5 cancers -South Africa. Breast , cervix ,Unknown Primary , Colorectal cancer and Uterus.. Breast cancer 22%. . Life time risk 1:28; white women 1:11 and black 1:51.. 1 in Breast Cancer: Why the Environment MattersA woman has a 1 in 8 chance of developing breast cancer in her lifetime, according to the American Cancer Society. It is the second most common cancer a L. MEYSKENS, D. (32, 33), and hormonal (42, 46, (60, 78). 57, 66, cancer in is less Klinefelter'n syndrome with male authors measured et al. the formation ofestrone results rerrmin in males been repo . Breast Cancer | . Epidemiology- Australia. Australian Institute of Health and Welfare 2014. ACIM (Australian Cancer Incidence and Mortality) Books. Canberra. AIHW. Overall is the third leading cause of cancer.