PPT-Update on genetic testing for hereditary breast cancer synd

Kristin DePrince Mattie MS Licensed Certified Genetic Counselor William G Rohrer Cancer Genetics Program Objectives Describe current approaches to genetic testing for hereditary cancer syndromes. Kalyani Maganti, M.D. ASCO. Chromosomes, DNA, and Genes. Cell. Nucleus. Chromosomes. Gene. Protein. ASCO. Disease-Associated Mutations. A “mutation” is a change in the normal . coding sequence of a gene. James Ford, MD and Nicki Chun, . MS, . LCGC. Cancer . Genetics Clinic. Stanford Cancer . Center. November 5, 2015. Breast/ Ovarian Cancer Syndrome. . Breast cancer diagnosed in 1/8- 1/0 women in US. Breast Cancer Genes. Two genes associated with inheritance of breast cancer. Breast cancer gene 1 (BRCA1. ) – Chromosome 17. BRCA . 2 – Chromosome 13. When normal…. Both are tumor suppressor genes. Robert A. Somer, MD. Head, Medical Oncology and Hematology. Director, Office of Clinical Research. MD Anderson Cancer Center- Cooper. What is Cancer?. Official Definition: A malignant proliferation of cells that is a result of a . Alix . d’angelo,. . mgc. , . cgc. February 13, 2017. SYNDROME OVERVIEW. HEREDITARY BREAST CANCER. SYNDROMES WITH BREAST CANCER. Hereditary Breast and Ovarian Cancer syndrome (. BRCA1, BRCA2. ). Li-. {Template Slide Set}. 1. Overview. What are Hereditary Breast and Ovarian Cancer syndrome (HBOC) and Lynch . s. yndrome (LS)?. How common are LS and HBOC? . How do LS and HBOC affect individuals and families?. Page 1of 26UnitedHealthcare Commercial Medical PolicyEffective 01/01/2021Proprietary Information of UnitedHealthcare Copyright 2021United HealthCare Services IncUnitedHealthcareCommercial MedicalPolic Mary McCullum, RN, MSN, CON(C). Nurse Educator, Hereditary Cancer Program. BC Cancer Agency. September 22, 2017. Objectives. Identify hereditary polyposis syndromes. Review hereditary cancer/polyposis referral process. Laura . K. Fisher. , MS, CGC. Director . of Genetic . Counseling. October . 8, 2019. Outline. Genetic counseling. What happens at a genetic counseling appointment? . Who should see a genetic counselor?. Most of these lesions are benign. Breast cancer is 2. nd. most common cause of cancer deaths in women, following. carcinoma of the lung. . The clinical significance of the . benign. conditions:. 1- possible clinical confusion with malignancy. How common are BRCA1 and BRCA2 mutations in the general population? Inherited mutations in BRCA1 and BRCA2 are relatively uncommon in the general population. The carrier frequency is estimated to rang Prostate cancer is the most common cancer in males . M ost men develop prostate cancer by chance or as a result of risk factors that occur over the course of a lifetime. However, approximately 10 pe Uterine Cancer Most people develop uterine cancer by chance or as a result of risk factors that occur over the course of a lifetime. However, up to 10 % ( percent ) of people who are diagnosed with Azeez Farooki, MD. Attending Physician, Clinical Member. Memorial Sloan Kettering Cancer Center. New York, NY. Objectives. Elucidate the problem of aromatase inhibitor induced bone loss and increased risk of fractures in breast cancer.