PPT-Mainstreaming Genomic Medicine

post 100000 Genomes Project Update Haem SSG Nov 2018 Contents Genetics and genomics Background to 100000 Genomes Project Project progress What next Mainstreaming Genomic Medicine. livestock. Dr Indrasen Chauhan. Scientist, CSWRI, Avikanagar. Tonk-304501. – . B. ased . on individual records, pedigree or progeny performance or family performance. . SI=WT9 +1DMY90. Conventional selection . Early genomic theory. Nejati-Javaremi. et al (. 1997. ) tested use of genomic relationship matrix in BLUP. Meuwissen et al (. 2001. ) tested linear and nonlinear estimation of . haplotype. effects. Zhicong Huang, Erman Ayday, Jacques Fellay, Jean-Pierre Hubaux, Ari Juels. Presented by Chuong Ngo. The Genomic Future. The Genomic Future. The Genomic Future. The Genomic Future. The Genomic Future. Daniel Neafsey. April 19. th. , 2017. Institute for Disease Modeling Symposium. New data types and technologies. New investments in modeling needed. Malaria Genomic Epidemiology. COIL (Complexity of Infection by Likelihood). National Human Genome Research Institute. National Institutes of Health. U.S. Department of Health and Human Services. U.S. Department of Health and Human Services. National Institutes of Health. National Human Genome Research Institute. Abstract #461. Background - Crossbreeding. Harris and Johnson (2010) . used multibreed relationship matrix to obtain GEBVs in NZL. Olson et al (2010) . estimated MT multi-breed SNP effects and genomic breed composition. livestock. Dr Indrasen Chauhan. Scientist, CSWRI, Avikanagar. Tonk-304501. – . B. ased . on individual records, pedigree or progeny performance or family performance. . SI=WT9 +1DMY90. Conventional selection . Dairy Cattle. 9 million cows in US. Attempt to have a calf born every year. Replaced after 2 or 3 years of milking. Bred via AI. Bull semen collected several times/week. Diluted and frozen. Popular bulls have 10,000+ progeny. Skin SSG . May 2018. Catherine Carpenter-Clawson, Programme Manager, WE GMC. Courtesy of Genomics England. From . Genetics . to . Genomics. Genetic testing = single gene. (. s. ). or panels. . Exome sequencing = coding DNA . ETH Zürich. October 1, 2015. Mathias Humbert . Joint . work. with Erman Ayday, Jean-Pierre Hubaux, . Kévin Huguenin, Joachim Hugonot, Amalio Telenti. (. Human. ) System Security. 0. 1. 0. 0. 1. 1. Laura Yarram-Smith. SWGLH Solid Tumour Laboratory Lead. 20/09/2019. Breast Cancer Genomics. Genomics in England and Genomic Lab Hub. Genomic Test Directory. Genomic Biomarkers in Breast Cancer. Future technologies . Presentation by GPC/Protection Mainstreaming Task Team. Julien Marneffe, Philippines, December 2013. Objectives of workshop. Introduce Protection Mainstreaming . Present the 4 key Protection Mainstreaming principles. Dr. Breno Fragomeni. Assistant Professor. Animal Science - UConn. Where are the labels?. Introduction . Why genomic prediction?. Higher accuracy. Shorter generation interval . Higher genetic gain. Genetic gain per year. Working together towards a common strategy . Overview. Implementing Genomic Medicine. Vision. Scope & Purpose. Background. SNOMED CT Strategy . (what & how). Strategic objectives. Next steps.