PPT-DNA structure and organization

By Dr Mohammed Hosny Hassan Associate Professor of Medical Biochemistry Faculty of Medicine South Valley University Nitrogenous Bases Nitrogenous bases that enter in RNA amp DNA structure are either . 3.3.1: Outline DNA nucleotide structure in terms of sugar (deoxyribose), base. and phosphate.. 3.3.2: State the names of the four bases in DNA.. 3.3.3: Outline how DNA nucleotides are linked together by covalent bonds. Nucleic Acids. What do we know already?. i. . The nucleic acids DNA and RNA are polymers of nucleotides. Nucleotides consist of 3 parts. A 5-carbon sugar – ribose or deoxyribose. A phosphate group (acidic & negatively-charged). 2.6 Structure of DNA & RNA. Understandings:. The nucleic acids DNA & RNA are polymers of nucleotides.. DNA differs from RNA in the # of strands normally present, the base composition & type of pentose.. The bacterial chromosome is a double-stranded, circular DNA molecule associated with a small amount of protein. Eukaryotic chromosomes have linear DNA molecules associated with a large amount of protein. Essential idea: The structure of DNA allows efficient storage of genetic information.. There is 2m of DNA in each human cell, however the most cells in the human body have a diameter of 10 . μm. . This DNA is divided in chromosomes and coiled around proteins called histones so that it can be efficiently stored in each cell's nucleus. The human genome project which has decoded the case sequence for the whole 2m of the human genome requires a data warehouse (pictured) to store the information electronically. This should give a good idea of just how efficient DNA is at storing information and why it needs to be so.. DNA damage DNA gets damaged a lot ! DNA damage DNA gets damaged a lot! >200,000 events/human cell/day DNA damage Occurs 2 ways 1) spontaneously 2) mutagens : damage DNA Transposons Discovered by Barbara McClintock DNA GLOW Lab A new way to investigate DNA structure. V1.1: June 2018 © Copyright by Amplyus LLC, all rights reserved We bring the study of DNA structure to your hands Patent pending DNA GLOW Lab Lion. Lion!!!!. Words and Actuality. “Lion” is a word, not a real lion.. Scribbles on paper or images on a monitor or screen are not a real lion.. Scribbles . on paper or images . on . a . screen . The formation of a highly organized DNA-protein complex, termed as chromatin, which is a nucleoprotein complex completes the packing.. Chromatin can be defined as highly condensed chromosomes at metaphase stage, and very diffuse structures in course of . The helical structure of . DNA. Formation of Nucleotides. Structure of polynucleotide polymer. Each base has its preferred . tautomeric. form. Purine. and . Pyrimidine. Base . tautomers. ; are frequent sources of errors during DNA synthesis.  . Author: Michael Fenech. Affiliation: Genome Health Foundation, North Brighton, SA, 5048, Australia. Email: . mf.ghf@outlook.com. . Introduction. Life as we know it depends entirely on the capacity of cells to utilize energy and molecules in the environment for cellular function and reproduction. . Directions: Front of card write term. On back write definition and draw picture . Chromosomes. Thread-like structure made of coiled DNA. Gene. Segment of DNA that codes for a specific trait. Nucleotide. . What is DNA?. DNA is a . Nucleic Acid in the nucleus. Polymer of . Nucleotides. Each nucleotide consists of. Deoxy. ribose (5-carbon sugar) . Phosphate group. a nitrogen-containing base. Four bases. Mitosis, Protein . Synthesis. Week 8. 9/29 . DNA Replication . 11.1. Obj. TSW demonstrate base pairing rules of DNA Replication by constructing a 2-D model of DNA with paper. . P. 68 NB. Replication Video.