PPT-Diabetes Ketoacidosis in Pediatrics

Sarah Kandil MD November 14 th 2019 Date DisclosureCOI CoInvestigator for Pfizer PHASE 1 study assessing pharmacokinetics safety and tolerability of ceftazidimeavibactam cazavi in children. People with diabetes have high blood glucose also called high blood sugar or hyperglycemia Diabetes is a disorder of metabolism the way the body uses digested food for energy The digestive tract breaks down carbohydratessugars and starches found in DKA, a subset of ketoacidosis or ketosis in diabetic patients, is atype of acidosis that sually develops when insulin levels are too low or during prolonged fasting. DKA most commonly occurs in patie Care of Patients with Diabetes Mellitus. Marion Kreisel MSN, RN. Adult Health 2 NU230. Fall 2011. Insulin Physiology. http://www.youtube.com/watch?v=_w7u6ZzlaFc&feature=related. http://www.youtube.com/watch?v=hwE1osnb5qc. Diabetes Mellitus: Overview of the Disease and Its Treatment. Diabetes mellitus . Greek word for “fountain”. Latin word for “honey”. Disorder of carbohydrate metabolism. Deficiency of insulin. Dr. Debra Miller, Pediatrician. This reporter visited the office of Dr. Debra Miller, Pediatrician at South Coast Medical Center in Laguna Beach. . Pediatrics are the fourth most common specialty in American practice of medicine.. CLINICAL PATHWAYPage 1of 15ALGORITHMCLINICAL PATHWAYPage 2of 15TABLE OF CONTENTSAlgorithmTarget PopulationBackground DefinitionsInitial EvaluationCerebral EdemaClinical ManagementLaboratoryStudy Imagi Section L Pediatrics L1Diagnostic ProblemInvestigationRecommendationGradeade0MRI is the de31nitive examination for suspected congenital malformation of the brain providing the best de31nition of brain Children146s Hospital Los Angeles is ranked among the top hospitals in the nation for endocrinology and diabetes care on the US News World Report Best Children146s Hospitals list As one of the larges By . Dr.Tamara. . Kufoof. MBBS, Assistant Professor, . Pediatric Endocrinologist and Diabetologist, The Hashemite University. 2021/2022. Diabetes mellitus (DM) . . a common, chronic, metabolic disease characterized by . Objectives. Introduce a patient case on diabetic ketoacidosis (DKA). Discuss the clinical presentation of DKA. Review the differences between DKA and HHS. Guidelines for DKA treatment and best practices. October 2019. DKA background. Diagnosis. Hyperglycemia (glucose > 200). Acidosis (venous pH < 7.3). Ketosis (urine or serum ketones). Risk factors. Not previously diagnosed with diabetes. 1/3 of children with type 1 diabetes first present with DKA. TYPE 1 DIABETES. prevalence. ~1 in 400 children <20 years affected. lifetime risk ~1 in 250. incidence. 1 new case per ~5,000 children per year. incidence appears to be rising ~3%/year. most affected: 0–5 year range. Tom Heaps. Consultant Acute Physician. Case 1. 82-year-old Caucasian female with T2DM (>30 years) and HTN. BMI 19. Metformin. 500mg TDS , . Gliclazide. 40mg BD, . Ramipril. 5mg OD. Admitted with 1/52 of increasing drowsiness, confusion and reduced oral intake. page ITC1-2 page ITC1-5 Treatmentpage ITC1-9 Practice Improvementpage ITC1-14 page ITC1-16 Christine Laine, MD, MPHBarbara J. Turner, MD, MSEDSankey Williams, MDJennifer F. WilsonThe content of In the