PPT-Glycogen Biosynthesis and Metabolism – Part 3

Glucagon Signaling in the Liver Image from Hædersdal S et al 2018 Mayo Clinic Proceedings 932217239 Glucagon Signaling Primary target sites Liver Purpose to release glucose into the bloodstream. Marks. 5 marks. Conducting the experiment. 2 marks. Questions. 15 marks. Report. 13 marks. Quiz. Practical 15. Theoretical. 10. Midterm. Practical 25. Theoretical. 15. Final. Total marks= . 100 marks. Metabolism. Section 8.1: . Glycolysis. Section 8.2: . Gluconeogenesis. Section 8.3: . The Pentose Phosphate Pathway. Section 8.4:. . Metabolism of Other Important Sugars. Section 8.5:. . Glycogen Metabolism. Fat and Glycerophospholipid Synthesis. 1. 2. 3. 1. 2. 3. 1. 2. 3. Phosphatidic . Acid. Glycerol-3-P. Fat (Triacylglycerol). Glycerophospholipids. Fat Breakdown. Signaling. Catalysis. Glycero. Phospho. Integration of Metabolism. Sugar metabolism. Lipid metabolism. Amino acid metabolism. Amino acid metabolism. Nucleotide metabolism. 0. 2. 4H. . 4e- . a . 2H. 2. 0. Oxygen is the ultimate destination for electrons in respiration. In muscle the final products of glycogen breakdown depend on the type of muscle fiber.. Red muscle fibers. . many mitochondria and much myoglobin. . Glucose is converted primarily to pyruvate that. Chapter 14-23. Overview of Metabolic Pathways-I. Lecture 13. Chapter 14. Carbohydrate Metabolism: . Glycolysis, Gluconeogenesis & the Pentose phosphate pathway. Carbohydrate Metabolism. Fates of Glucose. Longyun Guo. 1. John Morgan. 1,2. 1. Department of Biochemistry. 2. Davidson School of Chemical Engineering. Purdue University. May 2, 2019. Background. Lignin is an essential biopolymer in plant secondary cell walls . Intermediary Metabolism. OR. Interrelationship Between Various Metabolic . Pathways. OR. Interdependence Of Metabolic Pathways. To Better Understand Metabolism Of Various Biomolecules . Metabolism of each . Regulation of . Glycogenolysis. Figure modified from . Yan, A., et al (2016) In J . Biol. . Sci. 12(12):1544-1554. and . Servier. Medical Art. GDP. cAMP. Protein Kinase A. (PKA). PKA. Regulation of . Gluconeogenesis continued…………………... Class name – IVH. Course name - ZOO-Biochemistry. (Rohit). Overview of Gluconeogenesis. First step (. Conversion of Pyruvate to Phosphoenolpyruvate. Objectives. Structure of Glycogen. . Anabolism Vs Catabolism mechanisms.. Glycogen storage disorders. . Overview of Glycogen Metabolism. Excess glucose stored as glycogen. Glucose units joined by . α. Found in liver and skeletal muscles.. Represents 10% of weight of liver and 1-2% of muscles.. Stored in large cytosolic granules.. Elementary particles, . β. -particles consist of 50,000 glucose residues.. &. The Pentose Phosphate Pathway. Dr. . Shaimaa. . Munther. . Glycogen Metabolism. A constant source of blood glucose is an absolute requirement for human life. Glucose is the greatly preferred energy source for the brain, and the required energy source for RBC and muscle, since it’s the substrate for anaerobic . 5 marks. Conducting the experiment. 2 marks. Questions. 15 marks. Report. 13 marks. Quiz. Practical 15. Theoretical. 10. Midterm. Practical 25. Theoretical. 15. Final. Total marks= . 100 marks. Mid term date: .