PPT-Epigenetics of Atherosclerosis

Yongmgei Liu MD PhD FAHA Wake Forest School of Medicine Claudia E Korcarz DVM Atherosclerosis Imaging Research Program University Wisconsin MESA Epigenomics Study in . Dr. Gehan Mohamed Dr. Abdelaty . S. hawky. Learning objectives.  . Definition . of arteriosclerosis and mention the three patterns of it?. Mention definition, risk factors, gross morphology, and common sites of atherosclerosis?. Kevin Ferriter. Mariah Minder. From Yesterday…. Do you think your brain cell and your blood cell have the same DNA sequence?. Genetics. Every cell contains all of your DNA. Not every cell expresses all of your DNA. -What is epigenetics? -Epigenetics and us -Past, present, and future You Are What Your Mother Ate:What is Epigenetics?Daniel Lieber DNA is the Source of Heritable Information in the Cell organism Crea By Krystian, Gabby, Yasmin, John. What is Atherosclerosis?. Atherosclerosis is a disease of the arteries characterized by the disposition of the plaques of fatty materials on their inner walls. . Arteriosclerosis is a general term for the thickening and hardening of arteries. Some hardening of arteries normally occurs when people grow older.. . Samudra. K. . Wijeratne. , Ph.D.. Dept. of Nutrition and Health Sciences, UNL. Processes in . Epigenetics. The . study of heritable changes in gene expression or cellular phenotype caused by mechanisms other than changes in the underlying DNA . http://www.knowabouthealth.com/wp-content/uploads/2010/06/mcdonalds_.jpg. http://emilyscarenhealth.wordpress.com/2011/10/04/attention-a-must-read-for-smokers/. Can “. nuture. ” change “nature” ?. Terms. Arteriosclerosis – hardening of the arteries. Atherosclerosis – a form of arteriosclerosis. Venosclerosis. Arteriolosclerosis . Step One of Atherosclerosis. Endothelium injured. The tunica interna is injured in some way by bloodborne chemicals, hypertension, components of cigarette smoke or viral or bacterial infections. Almost any type of chronic infection – including periodontal disease can cause the damage.. Overview. Buildup of plaque in arteries. Causes hardening of the arteries. Restricts blood flow. Atherosclerosis in the heart is called . Coronary Artery Disease. Sudden plaque rupture or clotting can cause the heart muscle to die.. Why is Atherosclerosis known as a heart disease?. Atherosclerosis is when there is a buildup of plaque on artery walls. This creates a smaller passageway for blood to go through, increasing blood pressure. Overview. Buildup of plaque in arteries. Causes hardening of the arteries. Restricts blood flow. Atherosclerosis in the heart is called . Coronary Artery Disease. Sudden plaque rupture or clotting can cause the heart muscle to die.. Overview: Why is it Called “Heart Disease”. Atherosclerosis is a type of arteriosclerosis (the hardening of the arteries.) . A thrombus (blood clot) can form because of the buildup of plaque.. Diseases that can develop from atherosclerosis : angina (chest pain), carotid artery disease, coronary artery disease, and kidney disease.. NORMAL ARTERIAL WALL. PROCESS OF ATHEROSCLEROSIS. RISK FACTORS OF ATHEROSCLEROSIS. COMPLICATIONS OF ATHEROSCLEROSIS. DEFINITION. Atherosclerosis. is defined as a progressive disease characterized by the accumulation of lipids and fibrous elements in the large arteries.. Epigenetics comprises (hereditary) changes in gene expression without altering the DNA sequence . Epigenetics is a biological subdiscipline that deals with questions of development, heredity, gene regulation and evolution . ‘Epi’: On top of. . Definition:. The . study of changes in organisms caused by modification of gene expression rather than alteration of the genetic code itself.. DNA. How many cell types are in the human body?.