PPT-Measurement of serum Uric

Acid Msc Duaa falah pharmacology and toxicology Uric acid It is the final breakdown product of purine metabolism it circulates in the plasma as sodium urate and is excreted by the kidney It is derived from nucleic acid that are ingested or come from destruction of tissue cell . Protein Electrophoresis . (SPEP). Lab 3. What does it mean ?. Serum protein electrophoresis is an easy method of separating serum proteins based on their net charge, size, and shape. . A small amount of serum is placed on a specific medium (such as agarose) and an electrical charge is applied. . INDEX. Intoduction to culture media.. Components of serum.. Advantages and disadvantages of serum media.. Advantages and disadvantages of serum free media.. CULTURE MEDIA = defined as growth media suitable for the in- vitro cell culturing of human or animal cells and the composition of components are known.. : . C1549H2430N408O448S8. Description. :. Pegloticase is a recombinant . procine. -like . uricase. drug indicated for the treatment of severe, treatment-refractory, chronic gout. Similarly to . rasburicase. hyperuricemia. , . recurrent attacks of acute arthritis associated with . monosodium . urate. . crystals in . leukocytes. . found in synovial fluid, . deposits of monosodium . urate. crystals in tissues,. Heart of England NHS Foundation Trust. Overview. Background. Diagnosis. Risk factors. Acute treatment. Long-term treatment. Pseudogout. Gout. Inflammatory arthritis due to monosodium urate crystal deposition. Dr.. Anil Kumar. (Medicine) Asst. Professor. . Dept. of VCC. GOUT. Introduction:. The term . “gout” . in general term refers to a form of inflammatory arthritis.. CREATININE. CLEARANCE. URIC ACID. Mohammed Al-Zubaidi, PhD. Laboratory Training. Introduction. The kidneys are two bean shaped . organs lying . retroperitoneally. on each side . of the . vertebral column slightly above . purine. bodies in blood pre gout.. Whereas, the kidney is unable to separate this combination of uric acid and . purine. bodies.. Then the uric acid salts accumulate in the blood.. PTO... Lifestyle Change in Patients with . Hyperuricemia. Subtitle. The amount of . urate. in the body, . depends . on the balance between dietary intake, synthesis, . and excretion.. .  . Hyperuricemia. Pathology Of Gouty Nephropathy. Uric acid crystals and . urates. are deposited in the kidney.. This leads to irritation and acute . inflammation,more. time, more deposition.. This deposits act as . . Mustafa Al-Badran . CABM FIBMS. Gout it is derived from the Latin word gutta, meaning "a drop" (of liquid) that flow in the joint causing the disease . the disease of kings" . "rich man's disease". excretion and urea cycle; regulation of urea cycle;. Nitrogen excretion:. Nitrogen excretion means elimination of nitrogen containing compounds from an organism.. Urine is the main rout for such excretion, also take place through feces.. Define gout . Describe outlines of treatment. Describe treatment of acute gouty arthritis . Describe the mechanism of action , clinical uses & side effects of drugs used in acute attacks. OBJECTIVES ( continue). Mohammed. M.B.Ch.B. / MSc. Clinical pharmacology. Gout. is a . metabolic. disorder characterized by . high levels of uric acid. in the blood (hyperuricemia) due to an imbalance between overproduction of uric acid and/or the inability to excrete uric acid .