PPT-STRESS-L Trial: STudy into the REversal of Septic Shock with Landiolol (Beta Blockade)

Site Initiation Visit Version 70 02 August 2019 Chief Investigator Dr Tony Whitehouse Funder NIHR Efficacy and Mechanism Evaluation EME programme. New KODAK TRIX Reversal Film 7266 offers finer grain and increased sharpness and includes EASTMAN KEYKODE Numbers for easy crossreference of shots in minutes not hours Reduced static support allows for a cleaner image throughout the filmmaking proce Bacteriology . (and Virology) . Disease or Symptom?. Typically what we think of as a disease is actually a symptom…. For example, when we think of the common cold, we think of a stuffed up nose, cough, fever, etc.. . Systematic Review and Meta-analysis. Introduction to Medicine – 1. st. Semester. Class 4, First Year. Prof. . Doutor. Armando . Teixeira. -Pinto. Prof. . Doutor. . Altamiro. Costa-Pereira. Summary. &. Quality Improvement Primer. Goals. Review epidemiology and patient impact of the sepsis continuum. Define the sepsis disease spectrum by reviewing . the . pediatric definitions . of SIRS, . sepsis. . Goals. Overview. Defining Adequate Neuromuscular Recovery. Defining Residual Blockade . Incidence of Residual Blockade. Incidence of Residual Blockade (cont). Neuromuscular Monitoring and Postoperative Residual Curarization Meta-analysis. Dr. Vida Hamilton. National Clinical Lead Sepsis. www.hse.ie/sepsis. Sepsis - 2. A dysregulated immune response to infection. Regulated. Innate & Adaptive. Cellular: Dendritic cells, T-cells, B-cells. Program Goals. ERAS Definition. Achieving ERAS. Goals of ERAS. Anesthesia Roles in ERAS. NMB and Reversal as an Element . of ERAS. Purpose of NMB and Types of NMBAs. Nondepolarizing NMBA Reversal. PRNB. B) Polyuria. . C) Oliguria.. 24-3-2016 (30mins). Dr Irfan Elahi AP Nephrology. Shock. Circulatory Shock. Inadequate tissue perfusion with a relatively or absolutely inadequate cardiac output.. COI Disclosures. Evans – Nothing to disclose. Thank You. Guidelines panelists. Group Heads. Methodologists. SCCM and ESICM . Participating societies. Reviewers. Dr. Phil Dellinger. Ms. Deb . Mcbride. Andrea Caballero, MD. January 15, 2015. LSU Journal Club. The . ProCESS. Investigators. N . Engl. J Med 2014; 370:1683-1693. May 1, 2014.. Background. . T. here are over 750,000 cases of severe sepsis and septic shock per year in the US. . MLP EM Education Curriculum. Dave Markel. September 15, 2015. What will be covered. Basic concepts and definitions. Initial management. Septic shock. Pearls and pitfalls. What will . not. be covered. Sri Venkateswara Institute of Medical College. Tirupathi. SHOCK. Shock is characterized by . systemic hypotension . due to either reduced cardiac output or reduced effective circulating blood volume. Corticosteroids. There is significant uncertainty regarding the use of corticosteroids in patients with severe CAP requiring ICU admission. Several RCTs and meta-analyses have suggested benefit of treatment with corticosteroids, however existing evidence is not definitive and corticosteroids have a range of potentially adverse effects. Further research can examine . patient . population not receiving neuromuscular blockade . reversal agent. Further research could look at 30 day outcomes following tracheal reintubation. Results . 52 patients required tracheal reintubation; 37 before and 15 after Sugammadex.