PPT-Genome 540: Discussion Section

Week 5 Dani Faivre Agenda HW Quick Recap HW4 Questions HW5 Introduction HW comments Testing Use test cases with known output Descriptions Descriptions should reflect some annotation from the . Shai. Carmi. Pe’er. lab, Columbia University. and. The Ashkenazi Genome Consortium (TAGC). Boston. September 2013. Outline. Ashkenazi Jewish (AJ) Genetics . and TAGC. Basic Variant Statistics. Utility in AJ Medical . 2. Some genomics history. 1995: first bacterial genome, . Haemophilus influenza. , 1.8 Mbp, sequenced at TIGR. first use of whole-genome shotgun for a bacterium. Fleischmann et al. 1995 became most-cited paper of the year (>3000 citations). Timetable for today. Time. Activity. 00:00. Introduction to the session. 00:10. Story cards . 00:20. Info cards. 00:30. Issue cards. 00:40. Discuss two key. issues. 00:45. Feedback your issues. What is DNA?. Discussion Section. Renee Barclay. Discussion section. Your tutor or Cluster forum will provide you with a sample Results section, . which you should use for the purposes of this assignment. . . You should on no account base your Discussion on the analysis of data that you and the students from your group collected as part of the DE100 project work. . On the role of genomic medicine in the practice of neurology, an update. The last 15 years set the stage for . g. enomic medicine. First Human Genome sequencing:. 6 to 8 years. $1 billion. Completed April 14, 2003. Past. . topics:. General programming tips. C/C tips and standard library. BLAST. Frequentist vs. Bayesian methods. Applications of HMMs. What discussion topics would you like?. Potential topics:. (Methods in comp-bio). Genome: the total number of genes in an individual.. Human Genome- approx. 20,000 genes on the 46 human chromosomes.. Human Genome Project (HGP). Ongoing effort to completely map and sequence our genome.. Key considerations:. Genes . Chromosomes. C value paradox. Gene regulation. Epigenetics. Transposable elements. DNA . ……..……..mRNA……….…….Protein . Plant . Estimated # genes. Arabidposis. Key considerations:. Genes . Chromosomes. C value paradox. Gene regulation. Epigenetics. Transposable elements. DNA . ……..……..mRNA……….…….Protein . Plant . Estimated # genes. Arabidposis. 6c. Chromosome Mutations. Learning Intentions. By the end of this topic you should be able to:. (c) Chromosome structure mutations. Define ‘chromosome structure mutation’ . Name 4 chromosome structure mutations . Applications of DNA Technology. Advances in gene manipulation have made many things possible. This section investigates 4 key areas where gene manipulations will affect our lives:. The Human Genome Project. G-OnRamp Beta Users Workshop. Wilson Leung. 07/2016. Outline. Obtain genome assemblies from NCBI. Transfer . large genomics datasets to Galaxy. Common bioinformatics file formats . D. atatypes in Galaxy. CSE291: Personal Genomics for . Bioinformaticians. 01/. 10/17. The personal genomics revolution. 23andMe. : >1 million customers . (. $200). Genographic. Project: . >800,000 customers ($150). Family Tree DNA: . emm1. invasive Group A . Streptococcus. isolated from Belgian patients during 1994˗2013 . J. Coppens. 1. , . B. B. . Xavier,. . J. Sabirova. 1. , C. Lammens. 1. , K. Loens. 2. , S. Malhotra-Kumar.