PPT-Antimicrobial Resistance in

N gonorrhoeae A Review INTRODUCTION Progressive antimicrobial resistance in Neisseria gonorrhoeae is an emerging public health threat The Public Health Agency of Canada the Agency released updated recommendations in July 2013 for the diagnosis treatment followup and reporting of gonorrhea. Regulations. An Environment of Change. Brian Lubbers, DVM, PhD, . DACVCP. Director of Clinical Microbiology. Changing Regulations. Cephalosporin . Extralabel. Use Restriction. FDA Guidance 209. FDA Guidance 213. . Dr Andrea Ammon, ECDC Director, . 27 June 2017, European Parliament. 0. 200. 400. 600. 800. 1000. 1900. 1920. 1940. 1960. 1980. 2000. 1918. Influenza pandemic. 1924. Plague: last human-to-human transmission. a pharmaceutical industry perspective. 17. th. November 2018. Dr Bryan Deane. Dept of Research, Medical & Innovation . Introduction – the ABPI; the biopharmaceutical industry. AMR: the issue. Antibiotics. Antimicrobial drugs naturally produced by microorganisms. Penicillium. . species: . Penicillins. Cephalosporium. . specis. : . cephalosporins. Streptomyces. . species:. . lincosamides. Dr. Rachel Levine. Pennsylvania Physician General . Antimicrobial Resistance (AMR). Antimicrobial resistance (AMR) is the change in microbes (e.g. bacteria, parasites and fungi) which enable them to withstand treatment by antimicrobial drugs, meaning that the drugs no longer work, or work less effectively. Insert your organisation’s name here . Insert presenter’s name here . #. worldantimicrobialawarenessweek. Overview. Antibiotics are . vital life-saving . medicines . Antimicrobial resistance is both a global and local problem. Therapy. The development of antimicrobial drugs represents one of the most important advances in therapeutics, both in the control or cure of serious infections and in the prevention and treatment of infectious complications of other therapeutic modalities such as cancer chemotherapy, immunosuppression, and surgery.. . MDR. was defined as acquired . non susceptibility. . to . at least one agent in three or . more antimicrobial . categories. ,. . XDR. was defined as . non susceptibility. . to . at least one agent in all but two or . Consequences of AMR. What can we do ?. Microbiology and the antibiotic apocalypse. Dr Dave Whitworth. dew@aber.ac.uk. Reader in Biochemistry. Microbiology and the antibiotic apocalypse. What are antibiotics ?. Resistance : T ackling a crisis for the health and wealth of nations The Review on Antimicrobial Resistance Chaired by Jim O’Neill December 2014 Contents What is antimicrobial resistance? RESISTANCE Interagency Task Force on Antimicrobial Resistance Co - Chairs: Centers for Disease Control and Prevention Food and Drug Administration National Institutes of Health Participating Agencie s CC – 14/ UNIT - 7. Azidothymidine Antibiotic Resistance. Zidovudine (AZT). A synthetic pyrimidine (thymidine) analogue. AZT is converted to its triphosphate form by cellular thymidine kinase. It binds preferentially to HIV – reverse transcriptase resulting in chain termination. . 1. 1. Antibacterial resistance in ophthalmic infections: a multi-centre analysis across UK care settings//BMC Infectious Diseases.- volume 19, Article number: 768 (2019) . Educational MODULE. November 2020. antibiotics and other antimicrobials becoming less effective. infections being increasingly difficult or impossible to treat.. For patients, this results in prolonged illness and sometimes death.. Learn more about AMR, its impact on the.