PPT-Electrophilic

Attack Electrophilic Aromatic Substitution Electrophile substitutes for a hydrogen on the benzene ring Mechanism gt Bromination of Benzene Requires a stronger electrophile than Br 2 Use a strong Lewis acid catalyst FeBr. 15-8. Benzene undergoes substitution reactions with electrophiles.. Electrophiles attack benzene by substituting for a hydrogen atom, not addition to the ring.. Under the conditions of this type of reaction, ordinary non-aromatic conjugated polyenes would polymerize rapidly.. Preparation of . Haloalkanes. . by Halogenation. Preparation . Aryl Chlorides . by . Electrophilic. Substitution. Halogen . Exchange. Free radical chlorination or . bromination. of . alkanes. gives a complex 287 . Rings . Pyridne. , . quinoline. and . isoquinoline. Pyridne. Pyridine is a water -miscible liquid, b. p. 115 . oC. with . an unpleasant . odour. An . Excelent. polar . solvent, A . base (. Synthetic design involves two distinct steps: . (1) retrosynthetic analysis and . (2) subsequent translation of the analysis into a "forward direction" synthesis. . In the analysis, the chemist recognizes the functional groups in a molecule and disconnects them proximally by methods corresponding to known and reliable reconnection reactions.. 16-6. Naphthalene is activated toward electrophilic substitution.. Naphthalene undergoes electrophilic substitution rather than addition.. Naphthalene is activated with respect to electrophilic aromatic substitution. Bromination at C1 occurs without a catalyst under mild conditions.. of Alkenes: Addition Reactions. Disparlure: sex attractant of the female gypsy moth.. (A type of . pheromone.. ). 2. I. Hydrogenation of Alkenes. Addition. Reactions. oleic acid. (unsaturated). stearic acid. e. nergies & . t. ransition states. 7.2 Review of acid-base reaction mechanisms. 7.3 Writing reactions as transformations. 7.4 Substitution reactions. 7.5 Addition reactions. 7.6 Elimination reactions. Newehy. Chemistry Department, College of Science, King Saud University. http://fac.ksu.edu.sa/melnewehy. Aromatic . Compounds. The Structure of Benzene Ring. - . Benzene. is . the . parent hydrocarbon of . . as a tool for structure determination. Experimental:. Dissolve the sample in DCM (1 mL). Add . dropwise. a 1% . bromine solution. of DCM. Positive test, if red color disappears . Conclusion:. The sample contains a multiple bond, which undergoes . Newehy. Chemistry Department, College of Science, King Saud University. http://fac.ksu.edu.sa/melnewehy. Unsaturated Hydrocarbons. Alkynes. - . Alkynes. are . ydrocarbons. . that contain a . carbon–carbon . BY. Ronald Mensah. Introduction . Fluorination methods. Fluorination in Medical chemistry. Conclusion . Writing Component. References . Questions. Outline . Introduction . What is fluorine?. Location on the periodic table . Fall . 2018. Schedule of . day. PPE . and Pre-lab check . – at the door. Quiz. Recitation. Safety. Put bags away. Goggles. Gloves. Lab Coat. Lab part 1. IR . Review. Lab part 2. Due . Dates. . Today. Arenium Ion Mechanism . Some Aromatic Electrophilic Substitution Reactions Viz. Nitration, Sulphonation, Halogenation, Friedel- Crafts Reaction. Orientation & Reactivity in Mono Substituted Benzene. Teerawat. . Songsichan. 1. st. June 2017. Laboratory of Synthesis and Natural Products (LSPN). Content. 1. Introduction. 2. Electrophilic Fluorination. 2.1 Metal-Catalyzed Fluorination Involving Enolates.