PPT-Molecular Structures CH 4

Gumdrop Molecule Activity Draw the L ewis dot structure for the molecule Use gumdrops marshmallows and toothpicks to build a 3D representation of the molecule Gumdropatom Toothpickbond Small marshmallowshared electron pair. Over the past decade an ever growing arsenal of techniques has helped researchers dissect the innermost secrets of the cell and develop new ways to detect and attack disease These techniques also have been used to produce vast amounts of once rare d Damjan. . Temelkovski. Dr.. . Tamas. Kiss. Dr.. Gabor . Terstyanszky. University of Westminster. Molecular Docking. a.k.a. . in-. silico. docking. Simulating the interaction between two molecules: . Chapter 9. Molecular Shapes. Section 9.1. Lewis structures only provide a 2-D representation of a molecule. However, by including the bond angles of molecules, a more accurate 3-D representation can be achieved. MOLECULAR BIOLOGY TECHNIQUES II.. Polymerase Chain Reacton – PCR. DNA sequencing. Amplification of specific DNA fragments. MOLECULAR BIOLOGY – PCR. Cloning and/ or isolation from a genomic library . Andy Pon, . Doug . Johnstone. ,. Michael J. Kaufman. ApJ. , submitted May 2011 . Ridge et al. (2006). Observed. (FWHM = 1.9 km / . s. ). Thermal broadening alone. (FWHM = 0.2 km / . s. ). 12. CO J = 1-0. Spring . 2012. “Problems” with morphological. data…. Convergence and parallelisms. Reduction and character loss. Phenotypic vs. genotypic differences. Evaluation of homology. Misinterpretation of change or polarity. Yu-Shan . Lin (YSL). Department of . Chemistry. Tufts . University. Simulate how molecules move. Molecular dynamics simulations. km. hr. v. . (0). = . =. . 100. = 1000 kg. = . −. 7000 N. m. s. 2. Chemistry GT 3/20/15. Drill. Calculate the percent composition of Na. 2. SO. 4. .. HW: Molecular Formula WS (pg. 4). MM. =142.05 . g. /mol. 32.37% Na, 22.58% S, 45.05% O. Chem. Joke of the Day. The photon checked into a hotel. What did it say when the bellhop asked for its bag?. MMPBSA. D. G. free. D. G. bound. (1) Use free energy perturbation methods to estimate relative free energies. . DD. G =. D. G. free. - . D. G. bound. how to estimate free energies?. D. G?. ?. (2) Estimate potential of mean force along pathway? (but, what. Not Quite Ready . for Prime Time. Scott Kopetz, MD, PhD. . Department of GI Medical Oncology. MD Anderson Cancer Center. NOT YET. YES. Individual Biomarkers versus . Molecular Subtypes. Individual biomarkers:. Root Mean Squared, Effusion, Real Gases. Kinetic Molecular Theory of Gas. What is Kinetic energy?. Energy of motion. Kinetic theory of gases. Assume molecules are point masses (possess mass but no volume). A liquid in which a substance dissolves. Solvent. Water. MOLECULAR MOVEMENT. Nature adores balance. Wind. Hot air moving toward cold air. Wicking. Water moving from wet to dry. MOLECULAR MOVEMENT. Movement of molecules from . Mrs. Page. Essential Idea. Lewis (electron dot) structures show the electron domains in the valence shell and are used to predict molecular shape. .. Nature of Science. Scientists . use models as representatives of the real world – the development of the model of molecular shapes (VSEPR) to explain observable properties.. Homologous structures. Human Arm . Bat Wing . Whale Flipper. . Analogous. Structures . Similar functions but NOT structurally related. . Insects are arthropods and birds are vertebrates. . The wing of a bird and the wing of a butterfly are examples of .