PPT-Stretching DNA in Nanochannels

Kevin D Dorfman University of MinnesotaTwin Cities DMR 1206045 A major challenge in genomic medicine is obtaining kilobase scale genomic information such as rearrangements related to cancer A potential solution to this problem is nanochannel mapping where the DNA are extended in small channels The configuration and dynamics of channelconfined polymers like DNA was considered a solved question for the past 30 years However recent theoretical work by the PI indicates that the existing models are not applicable to emerging technologies The goal of this project is to obtain experimental data on the properties of DNA in nanochannels allowing the PI to test the prevailing . brPage 1br Taken from Stretching by Bob Anderson OMPUTER ESK TRETCHES brPage 2br EFORE ORK TRETCHES Taken from Stretching by Bob Anderson . “One Cannot think well, love well, sleep well, if one has not dined well”.. - Virginia Woolf -. Josh Salinas. Shea Anderson. Grant Johannes. OVERVIEW. Basic physical activity information. Examples of short and effective workout routines. Section B- Exercise Physiology . Increased range of movement/ reduce injury. Adopt held or aesthetic positions in gymnastics. Can reach a ball or player in game better. Can apply more power/ longer levers in athletic examples. . Care. Chapter 11. Principles of Flexibility Training. Flexibility training is a systematic program of stretching exercises designed to . progressively. increase the range of motion (ROM) of joints over time.. Chapter 10 Textbook. Course Packet page 26. The ability to move the joints through a full range of motion. FLEXIBILITY. a . type of sports fitness routine in which momentum and active muscular effort are used to stretch and the end position is not held . Ashley White. Fitness Training Steps. 1) warm-up *. 2) workout. 3) cool-down*. Warm Up: Pre Exercise. Dynamic stretch:. . ~ stretching while in a range of motion. Dynamic Examples. Toe raises. Leg raises: front and back. Factors that influence flexibility. 1- Joint structure. The type of joint determine the degree of ROM. For example; a ball-and-socket joint, like shoulder has greater ROM than a hinge joint like wrist. . Physiology of Training. PE 254. Muscle Physiology. Muscles consist of many . muscle fibers (cells). connected in bundles . Muscle fibers are made up of . myofibrils. Strength training increases the number of myofibrils and the size of muscle fibers = . 11-5. IR spectroscopy. . measures the vibrational excitation of atoms around the bonds that connect them.. The positions of the absorption lines are related to the types of functional groups present.. & . ExRx. Team banana. Flexibility. The ACSM recommends a minimum of flexibility training 2-3 days a week. Stretches should be held from 10-30 seconds to mild discomfort, 3-4 reps per stretch. Static Stretching. 7. Lactose digestions in . E. coli. begins with its hydrolysis by the enzyme . -. galactosidase. , . lacZ. , is part of a . coordinatley. regulated operon containing the genes required for lactose utilization. Which of the following figures correctly depicts the interactions at the . I can define flexibility and the things that limit Range of Motion. I can explain the agonist/antagonist relationship between muscles. I can compare and contrast the 5 different stretching techniques. DNA damage DNA gets damaged a lot ! DNA damage DNA gets damaged a lot! >200,000 events/human cell/day DNA damage Occurs 2 ways 1) spontaneously 2) mutagens : damage DNA Transposons Discovered by Barbara McClintock physical exercise.  in which a specific . muscle.  or . tendon.  (or muscle group) is deliberately flexed or stretched in order to improve the muscle's felt . elasticity.  and achieve comfortable .