PPT-Ledipasvir-Sofosbuvir RBV in HCV GT 1,4 and Advanced Liver Disease

Author : alida-meadow | Published Date : 2018-11-06

SOLAR1 Cohorts A and B Phase 2 Treatment Naïve and Treatment Experienced Charlton M al Gastroenterology 2015 14964959 Source Charlton M et al Gastroenterology

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Ledipasvir-Sofosbuvir RBV in HCV GT 1,4 and Advanced Liver Disease: Transcript

SOLAR1 Cohorts A and B Phase 2 Treatment Naïve and Treatment Experienced Charlton M al Gastroenterology 2015 14964959 Source Charlton M et al Gastroenterology 2015 14964959. ELECTRON (Overview): 6 parts, 22 arms. Phase . 2. Treatment. Naïve and Treatment . Experienced. Source: . Gilead Sciences, . Inc. Sofosbuvir. Summary of ELECTRON Trials Design (1 of 2). Part 1 . - . Hepatitis-2015. Orlando. , USA. July 20 - 22 2015. The Growing Epidemic in HCC from Hepatitis/NASH Cirrhosis in American Veterans. Implications and Economic burdens for the Health Care in the United States and the World!. (. Epclusa. ). Prepared by. : H. Nina Kim, MD MSc and David . Spach. , MD. Last . Updated: . July . 8, . 2016. Background and Dosing. Sofosbuvir-Velpatasvir. (. Epclusa. ). Sofosbuvir-Velpatasvir. (. . and HIV Coinfection. NIAID ERADICATE Trial. Phase . 2a. Treatment. Naïve and Treatment . Experienced. Osinusi. . A, et al. JAMA. 2015;313:1232-9. . HIV Coinfection. Source: . Osinusi. A, et al. . ION-4. Phase . 3. Treatment. Naïve and Treatment . Experienced. Naggie. S, . et al. . N . Engl. J Med 2015;378:705-13.. HIV Coinfection. Source: . Naggie. S, et al. N . Engl. J Med 2015;378:705-13.. NIH SPARE. Phase . 2. Treatment. . Naïve . (unfavorable baseline treatment . characteristics). Osinusi. A, et al. JAMA. 2013;310:804-11.. Source: . Osinusi. A,. . et al. . JAMA. 2013;310:804-11.. SIRIUS. Phase . 2 . Treatment. . Experienced. Bourliere. M, et al. Lancet Infect Dis. . 2015;15:397-404.. Source: . Bourliere. . M, . et al. . Lancet Infect Dis. 2015;15:397-404.. Ledipasvir-Sofosbuvir in Treatment-Experienced . rd. DAA in HCV Genotype 1 . NIAID SYNERGY: Genotype 1. Phase . 2. Treatment. . Naïve . (unfavorable baseline treatment . characteristics). Kohli. . A, et al. . Lancet. 2015:385:1107-13.. Source. VALENCE Trial. Phase . 3. Treatment. Naïve and Treatment . Experienced. Zeuzem. S, et al. . N . Engl. J Med. 2014;370:1993-2001. Source: . Zeuzem. S, et al. N . Engl. J Med. 2014;370:1993-. 2001.. in Genotype 3. ASTRAL-3. Phase 3. . Treatment. . Naïve & Experienced. Foster GR, . et al. . N . Engl. J Med. . 2015. ;373:2608-17.. *Published in tandem with ASTRAL-2 Trial. Source: Foster GR, . ASTRAL-2*. Phase 3. . Treatment. . Naïve & Experienced. Foster GR, . et al. . N . Engl. J Med. . 2015. ;373:2608-17.. *Published in tandem with ASTRAL-3 Trial. Source: Foster GR, . et al. N . NIAID Retreatment. Phase . 2a . Treatment. . Experienced. Osinusi. A, . et al. . Ann Intern Med. 2014;161:634-8.. Source: . Osinusi. A, et al. Ann Intern Med. 2014;161:634-8.. Ledipasvir-Sofosbuvir Retreatment of SOF RBV Failure in HCV GT 1. IAPAC African Regional Capacity-Building Hub. Based in Johannesburg, South Africa. Mission: Strengthen clinician capacity to deliver HIV, HBV, and HCV treatment . Partners include:. . Supported through an educational grant from: . Sameh W. Boktor, MD, MPH. Medical Epidemiologist. Pennsylvania Department of Health. Harrisburg, Pennsylvania. Disclosures. Off-label and/or investigational use of pharmaceuticals may be discussed in the presentation. This disclosure is to ensure participants in the activity may formulate their own judgments regarding the presentation..

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