PPT-Sofosbuvir + Ribavirin in HCV Genotype 1

Author : pamella-moone | Published Date : 2017-05-22

NIH SPARE Phase 2 Treatment Naïve unfavorable baseline treatment characteristics Osinusi A et al JAMA 201331080411 Source Osinusi A et al JAMA 201331080411

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Sofosbuvir + Ribavirin in HCV Genotype 1: Transcript

NIH SPARE Phase 2 Treatment Naïve unfavorable baseline treatment characteristics Osinusi A et al JAMA 201331080411 Source Osinusi A et al JAMA 201331080411. + Sofosbuvir in HCV GT 1-4 and HIV Coinfection. ALLY-2 Study. Phase 3. . Treatment. -. Naïve . and . Treatment-Experienced. Wyles. DL, . et al. . N . Engl. J Med. 2015;373:714-25.. Source: . Wyles. RESPOND-2. Phase . 3. Treatment. . Experienced. Bacon BR, et al. N . Engl. J Med. 2011;364:1207-17.. Source: . Bacon BR, et al. N Engl J Med. 2011;364:1207-17.. Boceprevir for Retreatment of HCV Genotype 1 Infection . Hepatitis-2015. Orlando. , USA. July 20 - 22 2015. The Growing Epidemic in HCC from Hepatitis/NASH Cirrhosis in American Veterans. Implications and Economic burdens for the Health Care in the United States and the World!. (. Epclusa. ). Prepared by. : H. Nina Kim, MD MSc and David . Spach. , MD. Last . Updated: . July . 8, . 2016. Background and Dosing. Sofosbuvir-Velpatasvir. (. Epclusa. ). Sofosbuvir-Velpatasvir. (. . +/- Ribavirin in HCV Genotype 1, 4 or 6. C-EDGE Treatment Experienced (TE). Phase 3. . Treatment. . Experienced. Kwo. P, . et al. . EASL 2015. Abstract P0886.. Source: . Kwo. P et al. EASL 2015. Abstract P0886.. Genotype . 2. . or 3 . FUSION. Trial. Phase . 3. *Note: Published . in . NEJM in tandem . with . POSITRON Trial (GT 2,3 Unable to receive PEG). Treatment. . Experienced. Jacobson I, et al. N . Engl. VALENCE Trial. Phase . 3. Treatment. Naïve and Treatment . Experienced. Zeuzem. S, et al. . N . Engl. J Med. 2014;370:1993-2001. Source: . Zeuzem. S, et al. N . Engl. J Med. 2014;370:1993-. 2001.. -. 0938 in GT 1-4. QUANTUM. Phase . 2b. Treatment. . Naïve . Lalezari. JP, et al. EASL. 2013; Abstract 845. . Source: . Lalezari. JP, et al. EASL. 2013; Abstract 845. . Sofosbuvir, Ribavirin, & GS-0938 in . ASTRAL-2*. Phase 3. . Treatment. . Naïve & Experienced. Foster GR, . et al. . N . Engl. J Med. . 2015. ;373:2608-17.. *Published in tandem with ASTRAL-3 Trial. Source: Foster GR, . et al. N . ). Slide deck prepared . by: . David H. Spach, MD and H. Nina Kim, MD MSc. Last . Updated: . October 23, . 2014. Robe. rt G. Gish MD. Professor, Consultant, Stanford University Medical Center. Senior Medical Director, St Josephs Hospital and Medical Center, Liver Program, Phoenix, Arizona. Interim Analysis of a French Multicenter Compassionate Use Program. Christophe Hézode,. 1. Victor De Ledinghen,. 2. Helene Fontaine,. 3. Fabien Zoulim,. 4. Pascal Lebray,. 5. Nathalie Boyer,. 6. NIAID Retreatment. Phase . 2a . Treatment. . Experienced. Osinusi. A, . et al. . Ann Intern Med. 2014;161:634-8.. Source: . Osinusi. A, et al. Ann Intern Med. 2014;161:634-8.. Ledipasvir-Sofosbuvir Retreatment of SOF RBV Failure in HCV GT 1. . with Advanced Liver Disease. ALLY-3+ Study. Phase 3. . Treatment. -. Naïve . and . Treatment-Experienced. Leroy V, . et al. . Hepatology 2016;63:1430-41.. Source: Leroy V, et al. Hepatology . 2016;63:1430-41.. ASTRAL-4. Source: Curry MP, et al. N Engl J Med. 2015;373:2618-28.. Treatment Naïve and Treatment Experienced, Phase 3. Sofosbuvir-Velpatasvir in Decompensated HCV Cirrhosis. ASTRAL-4: Study Features.

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