PPT-Ledipasvir-Sofosbuvir in GT1 or GT4 and HIV Coinfection

Author : pasty-toler | Published Date : 2017-05-09

ION4 Phase 3 Treatment Naïve and Treatment Experienced Naggie S et al N Engl J Med 201537870513 HIV Coinfection Source Naggie S et al N Engl J Med 201537870513

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Ledipasvir-Sofosbuvir in GT1 or GT4 and HIV Coinfection: Transcript

ION4 Phase 3 Treatment Naïve and Treatment Experienced Naggie S et al N Engl J Med 201537870513 HIV Coinfection Source Naggie S et al N Engl J Med 201537870513. JAMA 20153131232 9 HIV Coinfection brPage 2br Source Osinusi A et al JAMA 20153131232 9 Ledipasvir Sofosbuvir in GT1 with HIV Coinfection NIAID ERADICATE Trial Features NIAID ERADICATE Trial Design Open label phase 2 using fixed dose combination o + Sofosbuvir in HCV GT 1-4 and HIV Coinfection. ALLY-2 Study. Phase 3. . Treatment. -. Naïve . and . Treatment-Experienced. Wyles. DL, . et al. . N . Engl. J Med. 2015;373:714-25.. Source: . Wyles. ELECTRON (Overview): 6 parts, 22 arms. Phase . 2. Treatment. Naïve and Treatment . Experienced. Source: . Gilead Sciences, . Inc. Sofosbuvir. Summary of ELECTRON Trials Design (1 of 2). Part 1 . - . Matthew Luu, Yuan Fang (Pearl) Cai, Shiming Sun, . Ziyi Cheng. PHM142 Fall . 2016. Coordinator. : Dr. Jeffrey Henderson. Instructor: Dr. David Hampson. What is Hepatitis C? . Flaviviridae. virus family. Genotype . 2. . or 3 . FUSION. Trial. Phase . 3. *Note: Published . in . NEJM in tandem . with . POSITRON Trial (GT 2,3 Unable to receive PEG). Treatment. . Experienced. Jacobson I, et al. N . Engl. VALENCE Trial. Phase . 3. Treatment. Naïve and Treatment . Experienced. Zeuzem. S, et al. . N . Engl. J Med. 2014;370:1993-2001. Source: . Zeuzem. S, et al. N . Engl. J Med. 2014;370:1993-. 2001.. ASTRAL-1. Phase 3. . Treatment. . Naïve & Experienced. Feld JJ, . et al. . N . Engl. J Med. . 2015. ;373:2599-607.. Source: Feld . JJ. , et al. N . Engl. J Med. . 2015. ;373:2599-607.. Sofosbuvir-Velpatasvir. SOLAR-1 (Cohorts A and B). Phase . 2 . Treatment Naïve and Treatment Experienced. Charlton M, al. Gastroenterology. 2015; 149:649-59.. Source: Charlton M, . et al. . Gastroenterology. 2015; 149:649-59.. Presented by: . Fabian Cretu, Beverly-Ann Oliver, Kristina Miclat, Maeryl Sumagang. PHM142. September 25, 2018. PHM142 Fall . 2018. Instructor: . Ms. Maya Latif. Coordinator: Dr. J. Henderson. HIV. Amber Wheeler, MD. WIHS Scientific Meeting. June 30, 2014. Objectives. To discuss:. Background . Aims. Preliminary “rough” data. Future Directions. HIV-infected . persons have increased. odds of . NIAID Retreatment. Phase . 2a . Treatment. . Experienced. Osinusi. A, . et al. . Ann Intern Med. 2014;161:634-8.. Source: . Osinusi. A, et al. Ann Intern Med. 2014;161:634-8.. Ledipasvir-Sofosbuvir Retreatment of SOF RBV Failure in HCV GT 1. University of Chicago. Chicago, Illinois. Challenges in the Management and Treatment of HIV/Hepatitis C Virus Coinfection. FORMATTED: 05/02/2016. Chicago, Illinois: May 9, 2016. From . AI . Aronsohn. Sofosbuvir + Ribavirin to Prevent Post-Transplant HCV Recurrence Phase 2 Curry MP, et al. Gastroenterology . 2015;148:100-7. Treatment Naïve and Treatment Experienced Liver Transplantation Source: Curry MP, et . Sallie . Permar. , MD, PhD. Nancy C . Paduano. Professor and Chair of Pediatrics, Weill Cornell Medicine. Pediatrician in Chief. Age (. yrs. ). 0. 1. 2. 3. 17. 12. 13. 14. 15. 16. 19-24. 18. HIV-1 prevalence (%).

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