PPT-Simeprevir
Author : alida-meadow | Published Date : 2017-03-20
versus Telaprevir with PR in GT1 ATTAIN Trial Phase 3 Treatment Experienced Reddy KR et al Lancet Infect Dis 2015152735 Source Reddy KR et al Lancet Infect
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Simeprevir: Transcript
versus Telaprevir with PR in GT1 ATTAIN Trial Phase 3 Treatment Experienced Reddy KR et al Lancet Infect Dis 2015152735 Source Reddy KR et al Lancet Infect Dis 2015152735. ATTAIN. SMV + TVR placebo. + PEG-IFN + RBV. TVR + SMV placebo + PEG-IFN + RBV. Randomisation*. 1 : 1. Double-blind. ≥ 18 years. HCV genotype 1. HCV RNA ≥ 10,000 IU. /ml. Null or partial responders to . John J. . Faragon. , . PharmD. , BCPS, AAHIV-P. Regional Pharmacy Director, NY/NJ AETC. Pharmacist, Albany Medical Center. Objectives. Discuss recent guidelines . changes for HIV infection. Using . patient cases, discuss the role of . Genotype . 1 . (. Viral . Relapsers. ). PROMISE . Trial. Phase . 3. Treatment. . Experienced. Forns. X. , . et al. . Gastroenterology. 2014;146:1669-79.e3.. Source: . Forns. X. , et al. Gastroenterology. 2014;146:1669-79.e3.. Treatment –Experienced Genotype . 1 . ASPIRE Trial. Phase . 3. Treatment. . Experienced. Z. euzem. S. , . et al. . Gastroenterol. . 2014;146:430-41.. Source: . Zeuzem. S. , et al. . Gastroenterol. . + Sofosbuvir +/- Ribavirin in Genotype 1. COSMOS Trial. Phase . 2a, . Treatment . Naïve and Treatment Experienced. Treatment. Naïve and Treatment . Experienced. Lawitz. . E. , et al. Lancet. 2014;384;1756-65.. John J . Faragon. , . PharmD. , BCPS, AAHIV-P. Regional Pharmacy Director, . NY/NJ AIDS Education and Training Center . Pharmacist, HIV Medicine, Albany Medical Center. www.hcvguidelines.org. Released 1/29/14!. GT-1. C212 Trial. Phase . 3. Treatment. Naïve and Treatment . Experienced. Dieterich. . D. , et al. . Clin. Infect Dis. 2014;59:1579-87.. HIV Coinfection. Source: . Dieterich. D. , et al. . Clin.
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