PPT-Simeprevir in HIV Coinfection,

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GT1 C212 Trial Phase 3 Treatment Naïve and Treatment Experienced Dieterich D et al Clin Infect Dis 201459157987 HIV Coinfection Source Dieterich D et al

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Simeprevir in HIV Coinfection,: Transcript

GT1 C212 Trial Phase 3 Treatment Naïve and Treatment Experienced Dieterich D et al Clin Infect Dis 201459157987 HIV Coinfection Source Dieterich D et al Clin. JAMA 20153131232 9 HIV Coinfection brPage 2br Source Osinusi A et al JAMA 20153131232 9 Ledipasvir Sofosbuvir in GT1 with HIV Coinfection NIAID ERADICATE Trial Features NIAID ERADICATE Trial Design Open label phase 2 using fixed dose combination o ATTAIN. SMV + TVR placebo. + PEG-IFN + RBV. TVR + SMV placebo + PEG-IFN + RBV. Randomisation*. 1 : 1. Double-blind. ≥ 18 years. HCV genotype 1. HCV RNA ≥ 10,000 IU. /ml. Null or partial responders to . John J. . Faragon. , . PharmD. , BCPS, AAHIV-P. Regional Pharmacy Director, NY/NJ AETC. Pharmacist, Albany Medical Center. Objectives. Discuss recent guidelines . changes for HIV infection. Using . patient cases, discuss the role of . Genotype . 1 . (. Viral . Relapsers. ). PROMISE . Trial. Phase . 3. Treatment. . Experienced. Forns. X. , . et al. . Gastroenterology. 2014;146:1669-79.e3.. Source: . Forns. X. , et al. Gastroenterology. 2014;146:1669-79.e3.. Treatment –Experienced Genotype . 1 . ASPIRE Trial. Phase . 3. Treatment. . Experienced. Z. euzem. S. , . et al. . Gastroenterol. . 2014;146:430-41.. Source: . Zeuzem. S. , et al. . Gastroenterol. versus . Telaprevir. . with PR in GT1 . ATTAIN Trial. Phase . 3. Treatment. . Experienced. Reddy KR. , . et al. . Lancet Infect Dis. 2015;15:27-35.. Source: Reddy KR. , et al. Lancet Infect Dis. 2015;15:27-35.. . + Sofosbuvir +/- Ribavirin in Genotype 1. COSMOS Trial. Phase . 2a, . Treatment . Naïve and Treatment Experienced. Treatment. Naïve and Treatment . Experienced. Lawitz. . E. , et al. Lancet. 2014;384;1756-65.. John J . Faragon. , . PharmD. , BCPS, AAHIV-P. Regional Pharmacy Director, . NY/NJ AIDS Education and Training Center . Pharmacist, HIV Medicine, Albany Medical Center. www.hcvguidelines.org. Released 1/29/14!. Presented by: . Fabian Cretu, Beverly-Ann Oliver, Kristina Miclat, Maeryl Sumagang. PHM142. September 25, 2018. PHM142 Fall . 2018. Instructor: . Ms. Maya Latif. Coordinator: Dr. J. Henderson. HIV. . Case. 47-Year-Old . Man With Asymptomatic HIV Infection. Case (cont). Initial Clinical Presentation. Laboratory Results. HepaScore. ®. A Composite Biomarker Panel for Liver Fibrosis. Hepatic Steatosis in Patients With HIV/HCV Coinfection. Amber Wheeler, MD. WIHS Scientific Meeting. June 30, 2014. Objectives. To discuss:. Background . Aims. Preliminary “rough” data. Future Directions. HIV-infected . persons have increased. odds of . Antiretroviral. Agents . in Adults and Adolescents . January 2016. AETC . NCRC . Slide Set. About This Presentation. 2. July 2016. www.aidsetc.org. These slides were developed using the April 2015 guidelines, and updated in . Go to: pollev.com/CCO2. or scan the QR code below. *All responses are anonymous and cannot be linked to individual participants.. Contemporary Management of HIV: Managing HIV in Viral Hepatitis Coinfection. Mark Sulkowski, . MD. Professor of Medicine. Medical Director, Viral Hepatitis Center . Johns Hopkins University. Baltimore Maryland USA. Liver disease is the second leading specific causes of death amongst HIV-positive individuals in the D:A:D study.

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