PPT-1 CNS Infection Meninges and Prions

2 CNS Infection Meninges CNS infections most are due to sepsis Pathogenesis Hematogenous spread most common Traumatic implantation Local extension from nearby infection Ascent of peripheral nerve. rachnoid, ura Mater The meninges were discussed in lecture. Make sure you know the information which you were given. Brain stem: The brainstem is located at the juncture of the cerebrum and the spin Drs. Saberi and Syed are Clinical Instructors, Department of Medicine, StateUniversity of New York at Buffalo, Buffalo, NY, and Staff Physicians, TheResource Center, Diagnostic and Treatment Outpatien Bacterial Infections. Colonization by harmful bacteria. Using the body as resources to grow and reproduce. Battled by the immune system. Different numbers of bacteria needed to overwhelm the immune system and cause infection. STRUCTURE. A core nucleic acid - DNA or RNA. Nucleic Acid surrounded by a protein, called a capsid.. CLASSIFICATION. By genomes: DNA viruses, RNA viruses or retroviruses . (any . of a group of RNA viruses that insert a DNA copy of their genome into the . Prusiner. MD. 1942-present . KUMC Neurology Morning Report. Richard J. Barohn, MD. May 8, 2017. Stanley B. . Prusiner. Biography. YEAR. ACHIEVEMENT. 1942. Born in . Des Monies IA. 1896 Grandfather emigrated from Moscow to Sioux City, IA. Prions. are infectious agents composed of protein in . misfolded. form.. initially thought to be viruses which replicated slowly within their hosts, but no nucleic acid found associated with infectious material.. Atif. . Chohan. & Alex . Brown. What is CJD?. Degenerative brain disorder. Uncommon, usually fatal. Appears in older people, short duration. First described in 1920. Hans Gerhard . Creutzfeld. /. Ammari. & Bayan Khawaldeh .. Meningitis. Definition: . It is an inflammation of meninges.. The meninges. are the three membranes that cover the CNS (brain and spinal cord).. Septic Meningitis “Bacterial Meningitis”. Day 3. Meninges. Covers brain and Spinal cord. 3 layers. Dura. Arachnoid. Pia. Dura Mater. Outer most layer. Tough, white fibrous connective tissue. Contains many blood vessels and nerves. Forms sheath around spinal cord. /ISSN: 2160-4150/AJSC1205003 Review Article Meninges: from protective membrane to stem cell niche , Guido Fumagalli, Valeria Berton, Mauro Krampera, Francesco Bifari 93 Inflammation of the brain cortex is called encephalitis. Meningismus. refers to meningeal irritation not due to CNS infection. Meningitis -overview . AETIOLOGY . Neonatal period. lateral. . ventricles. Dr. Anna L. Kiss. Department. of . Anatómy. , . Histology. and . Embryology. Semmelweis University. Budapest. 2018. Prosencephalo. n. . (. yellow+red. ). telencephalon. . Discovery of Viruses. Beijerinck. (1897) coined the Latin name “virus” meaning poison. He studied filtered plant juices & found they caused healthy plants to become sick. Introduction. Viruses, . Assist. Prof. Dr. Hussein Al . Naji. Bovine spongiform encephalopathy (BSE) is a progressive, fatal, infectious neurologic disease of cattle that resembles scrapie of sheep and goats. It was first diagnosed in the UK in 1986. Approximately 200,000 cases of BSE have been diagnosed in cattle, almost all of which were in the UK. In 1992, at the peak of the UK outbreak, 37,280 cases were reported in a single year..