PPT-Regulation of Pyruvate Kinase

Allosterically activated by fructose16bisphosphate increase flow through glycolysis Allosterically inhibited by signs of abundant energy supply all tissues ATP acetylCoA and longchain fatty acids. C483 Spring 2013. 1. An . intermediate found in gluconeogenesis and not glycolysis is. A) 2-phosphoglycerate.. B) oxaloacetate.. C) . phosphoenolpyruvate. .. D) fructose 1,6-bisphosphate.. 2. In the Cori Cycle, _____ is transported through blood to the liver, where it is made into ________ and then ___________ for transport out of the liver.. Glycolysis. C483 Spring 2013. 1. The . conversion of pyruvate to ethanol also causes the ________. . A) oxidation of NADH . B) production of ADP . C) consumption of O2 . D) generation of an ion gradient across mitochondrial membranes . C483 Spring 2013. 1. Which of these enzymatic reactions is NOT a control point for glycolysis?. . A. . Phosphoglycerate. kinase. . B. Hexokinase. . C. Phosphofructokinase. . D. Pyruvate kinase. Pratt and . Cornely. Chapter 19. Regulation by Compartmentalization. Form of . reciprocal . regulation. Degradation vs biosynthesis. Requires transporters. Specialization of organs. Fuel Storage. Total amounts. In glycolysis, these enzymes are . Hexokinase. Phosphofructokinase. P. yruvate kinase. Phosphofructokinase is the key regulator of glycolysis in mammals. The enzyme is allosterically inhibited by ATP and allosterically stimulated by AMP.. Chapter 17 . Stryer. Short Course. Glucose Metabolism Overview. Gluconeogenesis. Glycogen . metabolism. Pentose Phosphate Pathway. Precursors for Gluconeogenesis. Names of compounds?. Type of reaction?. C483 Spring 2013. 1. An . intermediate found in gluconeogenesis and not glycolysis is. A) 2-phosphoglycerate.. B) oxaloacetate.. C) . phosphoenolpyruvate. .. D) fructose 1,6-bisphosphate.. 2. In the Cori Cycle, _____ is transported through blood to the liver, where it is made into ________ and then ___________ for transport out of the liver.. Kinections. Map P36507. MEK2/MAP2K2. P36507. -T230. -S216. +S226. +S222. B-. Raf. P15056. COT/MAP3K8. P41279. PDK1/PDPK1. O15530. MORG1. Q9BRX9. SGK1. O00141. BMAL1. O00327. T484. KRT8. P05787. S74. Kinections. Map P52564. PKR/EIF2AK2. P19525. DCTN1. Q14203. MKK6/MAP2K6. P52564. -Y219. +T211. +S207. MEKK1/MAP3K1. Q13233. COT/MAP3K8. P41279. ASK1/MAP3K5. Q99683. MEKK2/MAP3K2. Q9Y2U5. MEKK3/MAP3K3. Chapter 16, . Stryer. Short Course. Glycolysis Expectations. Memorize/learn Figure . 16.1. Know overall reaction and stages. Explain . chemical/physiological purpose . of each . step. Learn structures. Part II. Dr. Kevin Ahern. Glycolysis. Summary. Glucose 2 ADP 2P. i. 2 NAD. . Yields. 2 Pyruvate 2 ATP 2 NADH 2 H. . 2 H. 2. O . Glycolysis. Fermentation in Yeast/Bacteria. Glucose. GA3P. Richard R. Furman. Directory, CLL Research Center. Weill Cornell Medical College /. New York Presbyterian Hospital. BCR-associated Kinases:. Proven Effective Therapeutic Targets. Nat Rev . Immunol. 2:945. 2. Glucose used g/h. Time. Sources of Glucose & its Consumption. Exogenous (diet). Body glycogen. Gluconeogenesis. Gluco. = Glucose, neo= new, genesis= creation. http://www.medgadget.com/archives/img/Kidney05-full.jpg. Agreene@Albright.edu. Albright Chemistry and Biochemistry. Share your name . Your favorite thing/most interesting thing you learned in biochemistry I. What you are most nervous about this session. What you are most excited about this session.