PPT-Emergency Care of a Patient with Hemophilia

Robin Reid MD Clinical Director Mary M Gooley Hemophilia Center Hematologist and Medical Oncologist Rochester Regional Health July 2021 Outline History of the Mary M Gooley Hemophilia Treatment Center. Delete this slide before presenting. Anywhere you see . {insert your/child’s name – or other text in brackets} . highlight the words and brackets and type your/your child’s name or pertinent information. December 4, 2015. Developed through a. collaboration between:. Moderator. 2. Maria Elisa Mancuso, MD, PhD. Haematologist, . Angelo Bianchi Bonomi Hemophilia and Thrombosis Center. Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico. February 4. th. , 2011. The Child With Pain. Single Joint Involvement. Multiple Joint Involvement. With Fever. Septic arthritis/Osteomyelitis. Sympathetic arthritis. Foreign body with infection. Traumatic arthritis. organization that assists and advocates for the bleeding disorders community.. MISSION. [Your Name]. [Date]. First Responders . &. von . Willebrand. Disease. © 2015 Hemophilia Federation of America. All rights reserved.. Chemical Basis for Catalytic Activity. Enzymes promote . transition state. (. TS. ).. Transition state favored by tight binding. .. Figure depicts anti-CCR-5 “protease”.. Strategy. : Raise against TS analogs.. Introduction/Overview. Introduction/Overview (cont). Importance of Prophylaxis, and Limitations on Its Application, in Hemophilia B. Key Unmet Need in Hemophilia B:. Reducing Patient Burden of Disease. By: Nam-Y7. Hemophilia was first recognized by the Jews, but not officially named even in the ancient times. . In the 2. nd. century AD, the Talmud, a Jewish collection of Rabbinical writings said that the boys did not have to be circumcised if two brothers died of the disease. In 1800s, it became known as the Royal Disease because many people of royal families died or got the disease. Queen Victoria got Hemophilia but she survived. Alexei, the heir apparent to the Russian royal family, suffered from Hemophilia. In 1950s, the first treatment to hemophilia appeared. It was in a type called “fresh frozen plasma”. Nowadays, we are marching towards a cure but there are two treatments. One is called “gene therapy” and the other is called “Recombinant therapy”. A treatment for hemophilia is replacing old blood clots with new ones.. June. , . 2013. Roger L. Lundblad, Ph.D.. Consultant in Biotechnology. Chapel Hill, North Carolina. http://www.lundbladbiotech.com. And Adjunct Professor, Department of Pathology,. University of North Carolina, Chapel Hill, North Carolina. Sex-linked inheritance; almost all patients male. Female carriers may have mild symptoms. Most bleeding into joints, muscles; mucosal and CNS bleeding uncommon. Severity inversely proportional to factor level. A new ambition of the World Federation of Hemophilia. WFH Guidelines for the Management of Hemophilia. All recommendations are consensus based.. Srivastava A et al. Haemophilia. 2020;26(Suppl 6):1–158. . WVNHF. Amber Tichnell, Executive Director. Hemophilia and other bleeding disorders. The human body is made up of several clotting factors – Factors 1 through 13 plus Von . Willebrand. Factor. A person can have deficiencies in any of these factors. Veena Choubey, Rena Malik, and Luis Carlos Zapata Genetics Hemophilia is an X-linked recessive disorder that exists in two forms, hemophilia A and hemophilia B. Hemophilia A is characterized specif Dr. S. Parthasarathy . MD., DA., DNB, MD (. Acu. ), . Dip. Diab.DCA, Dip. Software statistics . PhD (. physio. ). . Mahatma . gandhi. medical college and research institute, . puducherry. , India. Alfonso Iorio, MD PhD. McMaster University, Canada. Alfonso Iorio. MD, PhD, FRCPC. Professor of Medicine. McMaster University. Disclosures. McMaster University has received research, consultancy and educational funding for Population PK projects from Bayer, .