Friday 29 January 2021 LESSON TITLE How did Penicillin improve the treatment of disease during the 20th century Complete the knowledge quiz on teams in the assignment section How did Penicillin improve the treatment ID: 1011451
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1. How has the understanding of disease changed from 1250?Friday, 29 January 2021LESSON TITLE: How did Penicillin improve the treatment of disease during the 20th century?Complete the knowledge quiz on teams in the assignment section.
2. How did Penicillin improve the treatment of disease during the 20th century?DevelopingTo describe the key features of the discovery of penicillin.SecuringTo explain the impact of penicillin in treating illnesses.MasteringTo reach a judgement on the effectiveness of penicillin.
3. Watch the video and be prepared to discuss these questions.Why was Penicillin so important?Who accidently discovered Penicillin?How?What was the problem with his work?Who later developed Penicillin?https://www.youtube.com/watch?v=PdWhVwiJWaU
4. How did treatment of disease improve during the 20th century?The work of Alexander FlemingThe work of Florey and ChainFactors contributing to the development of penicillinImpact of penicillin Task: Using the information on the following slide you need to complete the table showing the discovery of Penicillin. Who was most significant in the discovery and development of penicillin? Can you compare between the individuals? Explain your answer.
5. Stage One – Fleming’s discovery of penicillin (1928)Alexander Fleming was working on a way to deal with the bacteria he had seen infecting soldiers wounds in France during World War I. In 1928 he found what he had been looking for. He was working at St Mary’s Hospital, London. Going on holiday he left a pile of petri dishes containing bacteria on his laboratory bench. On his return he noticed there was mould on one of the dishes. Around the mould the bacteria had disappeared. Fleming carried out experiments with the penicillin mould on living cells making a list of the germs it killed. It did not seem to work on deeper infections and took time to make enough to use. Fleming wrote about penicillin in a medical journal but nobody thought his article was important.Stage Two – Florey and Chain’s research and trials (1938)In 1938 Florey and Chain were researching how germs could be killed and had read Fleming’s article. They tried to get funding from the government but were only given £25 as WWII was close to starting. Florey asked America for money and got enough to pay for 5 years research. Florey and Chain discovered that penicillin worked on mice but to treat people it was needed in large quantities. Florey and Chain began growing penicillin in what ever they could find. By 1941 there was enough penicillin to test it on one person. The volunteer was Albert Alexander, a policeman who had developed septicaemia. The penicillin worked and Alexander began to recover. However the penicillin ran out after 5 days and Alexander became ill again and died. Penicillin had shown that it worked and wasn’t harmful to the patient but they couldn’t make enough of it.Stage Three – Wartime need for penicillin (1941)Florey and Chain needed help to mass produce penicillin but English factories were too busy helping the war effort. So Florey went to America which coincided with the attack on Pearl Harbour bringing America into the war. The American government realised the potential of penicillin for treating wounded soldiers and made – interest free loans to US companies to buy the equipment needed for making penicillin. Soon British firms were producing it as well and over 2.3 million doses were used to treat allied wounded on D – Day.Stage Four – After the warAfter the war ended in 1945 penicillin began to be manufactured and used by everyone, not just the armed forces. This still took time but antibiotics became more and more common in the 1950s and 1960s, gradually turning from a ‘wonder – drug’ into just an ordinary, everyday life – saver!
6. Task: Rank the factors on slide 9 in order of importance and write a paragraph to justify your opinion. Can you compare between reasons?Be ready to share your ideas!Then: How far has the treatment of disease improved overall in the 20th century?Write a paragraph to explain your ideas. Consider both magic bullets and penicillin and consider any potential limitations. In my opinion I think that the treatment of disease as improved (a great deal, significantly, not at all, a little bit) in the 20th century. For example, we now have…
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