PPT-Inherited Coagulopathies in Children: Hemophilia

Andrew J Costandi MD MMM Childrens Hospital Los Angeles USC Keck School of Medicine Faculty Disclosures None Learning Objectives Upon completion of this activity participants will be able to. Nairobi, Kenya. June 24, 2013. Jim Munn, R.N., M.S.. Program Nurse Coordinator. University of Michigan HTC. Ann Arbor, MI, USA. Chair – WFH Nursing . Committee. Acknowledgement. : . Slides 20,21, 23-28 . Hemophilia. X-linked . recessive disorder . characterized by the inability . to properly . form blood clots. .. Until recently, hemophilia was untreatable, and only a few hemophiliacs survived to reproductive age because any small cut or internal hemorrhaging after even a minor bruise were fatal.. How would you describe yourself? . Make a list of 5 characteristics…. Essential Questions. How are inherited traits different from learned behaviors?. Vocabulary to Know:. Inherited trait. Offspring. (. H. aemophilia). By: Morgan Dirienzo. The Royal Disease. Alternate Names and Symptoms. Some alternate names for Hemophilia would be Haemorrhaphilia, or Von Willebrand disease. . The Symptoms for Hemophilia are…. By: . Cammie’s. Corner. Inherited traits. Every living thing has . traits. . that make it . unique. . . A . trait. is a quality or characteristic of a living . thing. Physical . features. The color of an animals’ fur .  . October 29, 2012. The J. Wayne Reitz Union at the University of Florida. 8:00 am – 6:00 pm.  . *Breakfast will be served 30 minutes prior to the beginning of the meeting. "Therapy for Inherited Retinal Disease; Quo Vadis".  . October 29, 2012. University o f Florida, . Gainesville, Florida. 8:00 am – 6:00 pm.  . *Breakfast will be served 30 minutes prior to the beginning of the meeting. "Entering the Era of Treating Retinal Degenerative Disease". THROMBOPHILIA. Defects in physiologic anticoagulant pathways. Increased production of procoagulant. Antithrombin deficiency. Protein C deficiency. Protein S deficiency. Factor V . Leiden. Prothrombin G20210A gene mutation. By: Nam-Y7. Hemophilia was first recognized by the Jews, but not officially named even in the ancient times. . In the 2. nd. century AD, the Talmud, a Jewish collection of Rabbinical writings said that the boys did not have to be circumcised if two brothers died of the disease. In 1800s, it became known as the Royal Disease because many people of royal families died or got the disease. Queen Victoria got Hemophilia but she survived. Alexei, the heir apparent to the Russian royal family, suffered from Hemophilia. In 1950s, the first treatment to hemophilia appeared. It was in a type called “fresh frozen plasma”. Nowadays, we are marching towards a cure but there are two treatments. One is called “gene therapy” and the other is called “Recombinant therapy”. A treatment for hemophilia is replacing old blood clots with new ones.. Sex-linked inheritance; almost all patients male. Female carriers may have mild symptoms. Most bleeding into joints, muscles; mucosal and CNS bleeding uncommon. Severity inversely proportional to factor level. Andrew J. . Costandi. , MD, MMM . Children’s Hospital Los Angeles. USC Keck School of Medicine. Faculty Disclosures. None. Learning Objectives. Upon completion of this activity, participants will be able to:. Traits are features or visible characteristics. Behavior is a way in which living this react or act to its surrounding environment.. Inherited . trait . :. Trait received by offspring from parent. Both physical or behavioral characteristics can be inherited. Behavioral trait is also called instinct.. The . changes to . the heart . affect the size and shape of . the heart . and can also affect the way the electrical system makes . the heart . beat.. Although inherited cardiomyopathy cannot be cured, in most cases living with it . . Chelsea Marion, MD. 1,4. , Oluwaseun Odewole, MD, MPH. 2,4. , Sheila Goel, MD. 3,4. . 1. Dept. of Pediatrics, Morehouse School of Medicine, Atlanta, GA. . 2. Dept. of Family Medicine, Morehouse School of Medicine, Atlanta, GA. .